The Struggle for the Union: The Constitutional Union Party in the Election of 1860

One of the most important and influential periods in our nation\u27s history, the outbreak of the Civil War occurred as a result of the pivotal presidential election of 1860. The Constitutional Union Party, less well known than the others, attempted to provide a national united force at a time of crisis; their goal was to support the Constitution and not divisive political policies. Despite their efforts in Northern and Southern states, their candidates did not capture any of the major offices and the Constitutional Union Party disbanded shortly after

The Photographs of Jacob Riis: History in Relation to Truth

This article discusses the photographs and writing of Jacob Riis, who was instrumental in informing middle and upperclass people in the 1870\u27s about the poverty and conditions in the slums. It suggests that Riis may have staged some of his photographs, and that he was not without bias in his reporting, but that his pictures and writing did help in charging the social reform movements

Rapid Tilt-Series Acquisition for Electron Cryotomography

Using a new Titan Krios stage equipped with a single-axis holder, we developed two methods to accelerate the collection of tilt-series. We demonstrate a continuous-tilting method that can record a tilt-series in seconds, but with loss of details finer than ∼4 nm. We also demonstrate a fast-incremental method that can record a tilt-series several-fold faster than current methods and with similar resolution. We characterize the utility of both methods in real biological electron cryotomography workflows. We identify opportunities for further improvements in hardware and software and speculate on the impact such advances could have on structural biology

The Impact of the Cold Pressor Test on Inter-Arm Differences in Blood Pressure

International Journal of Exercise Science 16(2): 875-884, 2023. A large inter-arm difference (IAD+; ≥10mmHg between arms at rest) in blood pressure (BP) at rest is linked to cardiovascular risk, and exercise can change this difference. As mechanisms for IAD are elusive, unique physiological stimuli may provide insight towards a better understanding of this phenomenon. The cold pressor test (CPT) has a potent effect on BP and acts primarily through sympathetic nervous system (SNS) stimulation, though the effects of SNS stimulation on IAD are unknown. Therefore, the purpose of the present study was to examine the effects of the CPT on IAD. BP was monitored simultaneously using two automated, auscultatory monitors (SunTech Tango) and a non-invasive hemodynamic device (Physioflow). Participants completed a CPT test, including a 15-minute rest, three pre-test BP measurements (averaged), and a three-minute water immersion (3°C; measurements at 30-sec and 2-min). Descriptive statistics were calculated, and a repeated measures ANOVA test used to compare both the absolute and relative IAD responses. The CPT induced an average absolute increase in IAD of 4.0 mmHg at 30-sec and 6.7mmHg at 2-min across all participants (P\u3c0.05). Differences in both the absolute and relative IAD responses to the CPT were noted between IAD- and IAD+ individuals (P\u3c0.05). Despite a consistent HR response to the CPT between groups, stroke volume was lower in IAD+ participants at 30-sec and 2-min. Sympathetic stimulation via the CPT induced changes in both the inter-arm difference in blood pressure and hemodynamics in young, apparently-healthy individuals

Review: The Journal of Dramaturgy, volume 19, issue 2

Contents include: For the Record; An Introduction; Recognition for City of Wine, Brian Quirt, recipient of the 2009 Elliott Hayes Award Introduced by LMDA President Shelley Orr; Brian Quirt\u27s Elliott Hayes Acceptance Speech Washington, D.C. Watergate Restaurant July 18, 2009; Being Dramaturgical, A Conversation about Geoff Proehl\u27s New Book Toward a Dramaturgical Sensibility; Beyond Hamlet: Three Theatre Developments in Denmark; The Alexandrinsky and Renaissancing the Cultural Theatre Medium; The Acting and Dramaturgy of Odin Teatret; A Production Dramaturg and an Installation Dramaturg Discuss Their Approaches to Making Art. Issue editors: D.J. Hopkins, Lauren Beckhttps://soundideas.pugetsound.edu/lmdareview/1039/thumbnail.jp

Effects of Very Low Nicotine Content Cigarettes on Smoking Behavior and Biomarkers of Exposure in Menthol and Non-menthol Smokers.

IntroductionBecause 30% of cigarettes sold in the United States are characterized as menthol cigarettes, it is important to understand how menthol preference may affect the impact of a nicotine reduction policy.MethodsIn a recent trial, non-treatment-seeking smokers were randomly assigned to receive very low nicotine cigarettes (VLNC; 0.4 mg nicotine/g tobacco) or normal nicotine cigarettes (NNC; 15.5 mg/g) for 20 weeks. On the basis of preference, participants received menthol or non-menthol cigarettes. We conducted multivariable regression analyses to examine whether menthol preference moderated the effects of nicotine content on cigarettes per day (CPD), breath carbon monoxide (CO), urinary total nicotine equivalents (TNE), urinary 2-cyanoethylmercapturic acid (CEMA), and abstinence.ResultsAt baseline, menthol smokers (n = 346) reported smoking fewer CPD (14.9 vs. 19.2) and had lower TNE (52.8 vs. 71.6 nmol/mg) and CO (17.7 vs. 20.5 ppm) levels than non-menthol smokers (n = 406; ps < .05). At week 20, significant interactions indicated that menthol smokers had smaller treatment effects than non-menthol smokers for CPD (-6.4 vs. -9.3), TNE (ratio of geometric means, 0.22 vs. 0.10) and CEMA (ratio, 0.56 vs. 0.37; ps < .05), and trended toward a smaller treatment effect for CO (-4.5 vs. -7.3 ppm; p = .06). Odds ratios for abstinence at week 20 were 1.88 (95% confidence interval [CI] = 0.8 to 4.4) for menthol and 9.11 (95% CI = 3.3 to 25.2) for non-menthol VLNC smokers (p = .02) relative to the NNC condition.ConclusionsAlthough menthol smokers experienced reductions in smoking, toxicant exposure, and increases in quitting when using VLNC cigarettes, the magnitude of change was smaller than that observed for non-menthol smokers.ImplicationsResults of this analysis suggest that smokers of menthol cigarettes may respond to a nicotine reduction policy with smaller reductions in smoking rates and toxicant exposure than would smokers of non-menthol cigarettes