4,165 research outputs found

    Dupin hypersurfaces in Lie sphere geometry

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    The method of moving frames in Lie sphere geometry has produced significant results in the classification of Dupin hypersurfaces in spheres. What is the secret of its effectiveness? The answer emerges in the classification of nonumbilic isoparametric surfaces in the space form geometries. Using the method of moving frames, the proof of this classification is an elementary exercise. The same proof classifies the cyclides of Dupin in M\"obius geometry and finally in Lie sphere geometry, where all nonumbilic Dupin immersions are Lie sphere congruent to each other.Comment: To appear in the Shoshichi Kobayashi Memorial Volume of Progress in Mathematics, Birkhause

    Compact surfaces with no Bonnet mate

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    This note gives sufficient conditions (isothermic or totally nonisothermic) for an immersion of a compact surface to have no Bonnet mate.Comment: 7 pages, LaTeX2

    Outstanding Educational Performance Awards: Highlighting Top Achieving Arkansas Schools, 2009

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    Since our founding in 2003, the mission of the Office for Education Policy has been to look at pressing issues through the lens of academic research and disseminate our findings to educators, policymakers, and other stakeholders around Arkansas. Every once in a while, however, we think it is okay to stray from issue analysis and simply share some good news! So, in this Arkansas Education Report (AER) we merely aim to highlight excellent performance and give our congratulations. To that end, we are happy to highlight the top performing schools around the state in an annual AER entitled the Outstanding Educational Performance Awards

    Enhanced tyrosine hydroxylase activity induces oxidative stress, causes accumulation of autotoxic catecholamine metabolites, and augments amphetamine effects in vivo.

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    In Parkinson\u27s disease, dopamine-containing nigrostriatal neurons undergo profound degeneration. Tyrosine hydroxylase (TH) is the rate-limiting enzyme in dopamine biosynthesis. TH increases in vitro formation of reactive oxygen species, and previous animal studies have reported links between cytosolic dopamine build-up and oxidative stress. To examine effects of increased TH activity in catecholaminergic neurons in vivo, we generated TH-over-expressing mice (TH-HI) using a BAC-transgenic approach that results in over-expression of TH with endogenous patterns of expression. The transgenic mice were characterized by western blot, qPCR, and immunohistochemistry. Tissue contents of dopamine, its metabolites, and markers of oxidative stress were evaluated. TH-HI mice had a 3-fold increase in total and phosphorylated TH levels and an increased rate of dopamine synthesis. Coincident with elevated dopamine turnover, TH-HI mice showed increased striatal production of
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