26 research outputs found
An automated software system to promote anticoagulation and reduce stroke risk: cluster-randomized controlled trial
Background and Purpose: Oral anticoagulants (OAC) substantially reduce risk of stroke in atrial fibrillation, but uptake is suboptimal. Electronic health records enable automated identification of people at risk but not receiving treatment. We investigated the effectiveness of a software tool (AURAS-AF [Automated Risk Assessment for Stroke in Atrial Fibrillation]) designed to identify such individuals during routine care through a cluster-randomized trial.Methods: Screen reminders appeared each time the electronic health records of an eligible patient was accessed until a decision had been taken over OAC treatment. Where OAC was not started, clinicians were prompted to indicate a reason. Control practices continued usual care. The primary outcome was the proportion of eligible individuals receiving OAC at 6 months. Secondary outcomes included rates of cardiovascular events and reports of adverse effects of the software on clinical decision-making.Results: Forty-seven practices were randomized. The mean proportion–prescribed OAC at 6 months was 66.3% (SD=9.3) in the intervention arm and 63.9% (9.5) in the control arm (adjusted difference 1.21% [95% confidence interval −0.72 to 3.13]). Incidence of recorded transient ischemic attack was higher in the intervention practices (median 10.0 versus 2.3 per 1000 patients with atrial fibrillation; P=0.027), but at 12 months, we found a lower incidence of both all cause stroke (P=0.06) and hemorrhage (P=0.054). No adverse effects of the software were reported.Conclusions: No significant change in OAC prescribing occurred. A greater rate of diagnosis of transient ischemic attack (possibly because of improved detection or overdiagnosis) was associated with a reduction (of borderline significance) in stroke and hemorrhage over 12 months.Clinical Trial Registration: URL: http://www.isrctn.com. Unique Identifier: ISRCTN55722437.%U http://stroke.ahajournals.org/content/strokeaha/early/2017/01/24/STROKEAHA.116.015468.full.pd
Barriers to a software reminder system for risk assessment of stroke in atrial fibrillation: a process evaluation of a cluster randomised trial in general practice
Background: Oral anticoagulants reduce the risk of stroke in patients with atrial fibrillation (AF), but are underused. AURAS-AF (AUtomated Risk Assessment for Stroke in AF) is a software tool designed to identify eligible patients and promote discussions within consultations about initiating anticoagulants.Aim: To investigate the implementation of the software in UK general practice.Design and setting: Process evaluation involving 23 practices randomly allocated to use AURAS-AF during a cluster randomised trial.Method: An initial invitation to discuss anticoagulation was followed by screen reminders appearing during consultations until a decision had been made. The reminders required responses, giving reasons for cases where an anticoagulant was not initiated. Qualitative interviews with clinicians and patients explored acceptability and usability.Results: In a sample of 476 patients eligible for the invitation letter, only 159 (33.4%) were considered suitable for invitation by their GPs. Reasons given were frequently based on frailty, and risk of falls or haemorrhage. Of those invited, 35 (22%) started an anticoagulant (7.4% of those originally identified). A total of 1695 main-screen reminders occurred in 940 patients. In 883 instances, the decision was taken not to initiate and a range of reasons offered. Interviews with 15 patients and seven clinicians indicated that the intervention was acceptable, though the issue of disruptive screen reminders was raised.Conclusion: Automated risk assessment for stroke in atrial fibrillation and prompting during consultations are feasible and generally acceptable, but did not overcome concerns about frailty and risk of haemorrhage as barriers to anticoagulant uptake
Implementation of the 2017 Berlin Concussion in Sport Group Consensus Statement in contact and collision sports : a joint position statement from 11 national and international sports organisations
The 2017 Berlin Concussion in Sport Group Consensus Statement provides a global summary of best practice in concussion prevention, diagnosis and management, underpinned by systematic reviews and expert consensus. Due to their different settings and rules, individual sports need to adapt concussion guidelines according to their specific regulatory environment.
At the same time, consistent application of the Berlin Consensus Statement’s themes across sporting codes is likely to facilitate superior and uniform diagnosis and management, improve concussion education and highlight collaborative research opportunities. This document summarises the approaches discussed by medical representatives from the governing bodies
of 10 different contact and collision sports in Dublin, Ireland in July 2017. Those sports are: American football, Australian football, basketball, cricket, equestrian sports, football/soccer, ice hockey, rugby league, rugby union and skiing. This document had been endorsed by 11 sport governing bodies/national federations at the time of being published.http://bjsm.bmj.comhj2018Sports Medicin
Patient and public involvement (PPI) in UK surgical trials: a survey and focus groups with stakeholders to identify practices, views, and experiences
Background and aims
Historically, patient and public involvement (PPI) in the design and conduct of surgical trials has been absent or minimal, but it is now routinely recommended and even required by some research funders. We aimed to identify and describe current PPI practice in surgical trials in the United Kingdom, and to explore the views and experiences of surgical trial staff and patient or public contributors in relation to these practices. This was part of a larger study to inform development of a robust PPI intervention aimed at improving recruitment and retention in surgical trials.
Methods
Our study had two stages: 1) an online survey to identify current PPI practice in active UK-led, adult surgical trials; and 2) focus groups and interviews with key stakeholders (surgical trial investigators, administrators, and patient or public contributors) to explore their views and experiences of PPI.
Results
Of 129 eligible surgical trial teams identified, 71 (55%) took part in the survey. In addition, 54 stakeholders subsequently took part in focus groups or interviews. Sixty-five (92%) survey respondents reported some kind of PPI, most commonly at the design and dissemination stages and in oversight or advisory roles. The single most common PPI activity was developing participant information sheets (72%). Participants reported mixed practice and views on a variety of issues including the involvement of patients versus lay members of the public, recruitment methods, use of role descriptions and payment for the time of PPI contributors. They suggested some solutions, including the use of written role descriptions and databases of potential PPI contributors to aid recruitment.
Conclusions
UK surgical trials involve patients and members of the public in a variety of different ways, most commonly at the beginning and end of the trial lifecycle and in oversight or advisory roles. These are not without challenges and there remain uncertainties about who best to involve, why, and how. Future research should aim to address these issues
The social context of women's sleep: Perceptions and experiences of women aged 40 and over.
This thesis, the first empirical study of the sociology of sleep conducted in the UK, takes a new approach to sleep research by examining the interrelationship between social context and the structuring of women's sleep. The thesis contends that women's sleep is influenced across the life course by the interaction of social roles and relationships and by life events and transitions. In conjunction with physiological factors, these dynamics define the nature of women's sleep, create the potential for disruption, and influence women's response to it. Using a multi-method approach, including focus groups, qualitative interviews, sleep-life grids, audio sleep diaries and a national sleep survey to record and interpret women's perceptions and experiences of sleep in everyday life, the thesis shows that for most women aged 40 and over, sleep disruption is a fact of life. It impacts on the quality of their lives and compromises their ability to function effectively. Sociotemporal factors associated with the institutionalised structures of paid work and retirement, women's relational responsibilities in the home, and life events such as divorce, the menopause and widowhood, often impede access to a good night's sleep. Women are proactive in responding to disruptions by adopting a range of sleep management strategies, but the constraints of their everyday lives may limit the degree of control they can exercise over strategy choice. The thesis concludes that not only is women's sleep structured by the socio-temporal realities of everyday life, but that it may also reaffirm and perpetuate the gendered roles and relationships which underpin, structure and constrain women's lives. Sleep thus becomes a lens through which to gain insights into the patterning of society with its gendered inequalities, as well as a fascinating topic in its own right
The social context of women's sleep : perceptions and experiences of women aged 40 and over
EThOS - Electronic Theses Online ServiceGBUnited Kingdo
A Bed of Roses or a Bed of Thorns? Negotiating the Couple Relationship Through Sleep
The convention in Western societies of partners sharing a bed is symbolic of their status as a couple, their commitment to the relationship, and their desire for shared intimacy. Yet for many couples, incompatibility as sleeping partners may threaten to undermine romantic notions of the double bed. This paper draws on in-depth interview and audio diary data from research into sleep in couples aged 20-59 (N=40) to examine how couples negotiate the spatial, temporal and relational dimensions of the sleeping environment. The paper contends that the management of tensions inherent in the sleeping relationship plays a key role in framing the couple identity over time, as well as reinforcing the gendered roles, power relationships and inequalities which underpin everyday life.Sleep, Couples, Interaction, Negotiation, Gender