34 research outputs found
A házi-mozi rendszerek beállítási problémáinak vizsgálata MATLAB program segítségével
Dolgozatom témája azzal kíván foglalkozni, hogy egy valós környezetben az 5.1-es hangrendszerből milyen paraméterek mellett lehet a legjobb hangzást, élményt kihozni. Milyen mérések szükségesek az optimális beállításhoz, a szoba akusztikájának, a hangfalak frekvencia görbéinek figyelembe vételével. A méréseket a MATLAB programkörnyezetben saját fejlesztésű, és beépített programokkal fogom elvégezni, és kiértékelni: Ezáltal áttekintést szeretnék adni a programkörnyezet működéséről, és megpróbálok rávilágítani a jelenleg működő egyszerűbb kalibráló módszerek közötti különbségekre is.MscPT
Investigation of Spinodal Decomposition in Isothermally Heat Treated LDX 2101 type Duplex Stainless Steel at 475 °C
Spinodal decomposition of the ferritic phase, a thermally induced phase transformation process is studied in an LDX 2101 type lean-duplex stainless steel by different examination methods. This phase transformation in duplex stainless steels has special importance because it is responsible for the so called "475 °C embrittlement". This deterioration process causes a decrease in toughness and corrosion resistance. Fe-Cr alloys, thus several stainless steels, are susceptible to the spinodal decomposition at intermediate and low temperatures (<600 °C). Therefore, it is important to study this phenomenon in novel lean-duplex stainless steels as well. Our results revealed that spinodal decomposition occurs to a lesser extent in the studied type of lean-duplex stainless steel but its effect is not negligible in applications
Right superior pulmonary vein parameter determined by three-dimensional transesophageal echocardiography is an independent predictor of the outcome after cryoballoon isolation of the pulmonary veins
Background: A direct comparison of three-dimensional transesophageal echocardiography (3DTEE)and cardiac computed tomography imaging has demonstrated good inter-technique agreement for thefollowing pulmonary vein (PV) parameters: the ostium area of the right superior PV (RSPV) and itsmajor (a) and minor axis (b) diameters, the left lateral ridge and the minor axis (b) diameter of the leftsuperior PV. Herein, under investigation, was the predictive value of these parameters for arrhythmiarecurrence (AR) after PV isolation with the 28 mm second generation cryoballoon (CBG2).Methods: One hundred eleven patients (67 men, mean age 58.06 ± 10.58 years) undergoing 3DTEEbefore PV isolation with the CBG2 for paroxysmal atrial fibrillation were followed. “Point by point” redointervention was offered in case of AR and reconnected PVs were defined.Results: During a mean follow-up of 617 ± 258.86 days, 65 (58.9%) patients remained free of AR.Longer RSPV b was found to be the only significant predictor for AR (hazard ratio [HR] 1.059; 95%confidence interval [CI] 1.000–1.121; p = 0.048). RSPV b ≥ 28 mm resulted in a threefold (HR 3.010;95% CI 1.270–7.134, p = 0.012) increase in the risk of AR. The association of RSPV b with AR wasindependent of the biophysical parameters of cryoapplications. In 25 “redo” patients, reconnections werefound 1.75 times more likely in the RSPV than in the other 3 PVs altogether.Conclusions: Right superior PV b measured with 3DTEE might be a significant predictor of AR afterPV isolation with the CBG2. In case of RSPV b exceeding 28 mm, alternative PV isolation techniquesor use of a larger balloon might be considered
Three-dimensional evaluation of the spatial morphology of stented coronary artery segments in relation to restenosis
To investigate the correlations between the three-dimensional (3D) parameters of target coronary artery segments and restenosis after stent implantation. Sixty-four patients after single, cobalt chromium platform stent (27 BM stents and 37 DES) implantation were investigated retrospectively 12 ± 6 months after the index procedure. 3D coronary artery reconstruction was performed before and after the stent implantation using appropriate projections by a dedicated reconstruction software. The curve of the target segment was characterized by the ratio of the vessel length measured at midline (arc: A) and the distance between the edge points of the stent (chord: C): A/C ratio (ACr). Age, diabetes and hyperlipidaemia were taken into account for the statistical evaluation. 22 patients were diagnosed with ISR, while 42 patients without any restenosis served as controls. The two groups did not differ regarding major cardiovascular risk factors, proportion of the treated vessels or the type of stents. Higher initial ACr values were associated with greater straightening of the vessel curvature in all groups (p < 0.001). Significant negative correlations were found in cases of proximal or distal edge bending angles (p < 0.001). Pre-stent edge bending angles < 7° often showed an increase after the stent implantation, while in case of higher initial values, the bending angles generally decreased. Using multivariate logistic regression modelling we found that the pre-stent ACr was an independent predictor of in-stent restenosis (odds ratio for 1% increase of the ACr: 1.08; p = 0.012). Changes of angles at the stent edges following stent implantation correlate with the initial local bending angles. The ACr predispose to chronic shear stress in the vessel wall, which may contribute to the pathological intimal proliferation
Three-dimensional evaluation of the spatial morphology of stented coronary artery segments in relation to restenosis
To investigate the correlations between the three-dimensional (3D) parameters of target coronary artery segments and restenosis after stent implantation. Sixty-four patients after single, cobalt chromium platform stent (27 BM stents and 37 DES) implantation were investigated retrospectively 12 ± 6 months after the index procedure. 3D coronary artery reconstruction was performed before and after the stent implantation using appropriate projections by a dedicated reconstruction software. The curve of the target segment was characterized by the ratio of the vessel length measured at midline (arc: A) and the distance between the edge points of the stent (chord: C): A/C ratio (ACr). Age, diabetes and hyperlipidaemia were taken into account for the statistical evaluation. 22 patients were diagnosed with ISR, while 42 patients without any restenosis served as controls. The two groups did not differ regarding major cardiovascular risk factors, proportion of the treated vessels or the type of stents. Higher initial ACr values were associated with greater straightening of the vessel curvature in all groups (p < 0.001). Significant negative correlations were found in cases of proximal or distal edge bending angles (p < 0.001). Pre-stent edge bending angles < 7° often showed an increase after the stent implantation, while in case of higher initial values, the bending angles generally decreased. Using multivariate logistic regression modelling we found that the pre-stent ACr was an independent predictor of in-stent restenosis (odds ratio for 1% increase of the ACr: 1.08; p = 0.012). Changes of angles at the stent edges following stent implantation correlate with the initial local bending angles. The ACr predispose to chronic shear stress in the vessel wall, which may contribute to the pathological intimal proliferation
Health and economic gain attributable to the introduction of the World Health Organization's drinking water standard on arsenic level in Hungary: A nationwide retrospective study on cancer occurrence and ischemic heart disease mortality.
The World Health Organization (WHO) estimates that 140 million individuals are at risk from consumption of drinking water containing arsenic at concentrations above the WHO guideline value of 10 μg/l. Arsenic mitigation is considered to be the most effective way to prevent arsenic related diseases. After joining the European Union, Hungary implemented a Drinking Water Quality Improvement Programme (DWQIP) to reduce levels of arsenic in drinking water below the WHO guideline value. But what impact did this have on health? We estimated the change in lifetime excess skin, lung, and bladder cancer risks and mortality from ischaemic heart disease (IHD) associated with chronic arsenic intake among those exposed before (2004-2007) and after (2014-2017) the implementation of DWQIP. A population-based risk assessment approach was used to assess lifetime excess cancer risk applying two scenarios for lung and bladder cancers. The economic benefits of the DWQIP were estimated by the combination of cost of illness and value per statistical life methods. Compared to the period before the DWQIP, its implementation was associated with a significant reduction in arsenic in drinking water [median: 3.0 μg/l interquartile range (IQR): 1.5-12.0 μg/l to median: 2.15 μg/l IQR: 1.0-5.79 μg/l]. The two scenarios were estimated to be associated with 225.2 and 35.9 fewer cancer cases each year. The number of annually prevented IHD deaths was estimated to be 88.9. It was estimated that the benefits of the DWQIP will outweigh its costs. We conclude that reducing arsenic levels in drinking water to 10.0 μg/l resulted in significant health and economic benefits. Our study goes beyond the existing research, offering both new insights into the impact of arsenic mitigation and providing a methodological template for similar studies in the many parts of the world that have yet to reduce arsenic exposure