1,435 research outputs found
A Holistic Usability Framework For Distributed Simulation Systems
This dissertation develops a holistic usability framework for distributed simulation systems (DSSs). The framework is developed considering relevant research in human-computer interaction, computer science, technical writing, engineering, management, and psychology. The methodology used consists of three steps: (1) framework development, (2) surveys of users to validate and refine the framework, and to determine attribute weights, and (3) application of the framework to two real-world systems. The concept of a holistic usability framework for DSSs arose during a project to improve the usability of the Virtual Test Bed, a prototypical DSS, and the framework is partly a result of that project. In addition, DSSs at Ames Research Center were studied for additional insights. The framework has six dimensions: end user needs, end user interface(s), programming, installation, training, and documentation. The categories of participants in this study include managers, researchers, programmers, end users, trainers, and trainees. The first survey was used to obtain qualitative and quantitative data to validate and refine the framework. Attributes that failed the validation test were dropped from the framework. A second survey was used to obtain attribute weights. The refined framework was used to evaluate two existing DSSs, measuring their holistic usabilities. Ensuring that the needs of the variety of types of users who interact with the system during design, development, and use are met is important to launch a successful system. Adequate consideration of system usability along the several dimensions in the framework will not only ensure system success but also increase productivity, lower life cycle costs, and result in a more pleasurable working experience for people who work with the system
The Use of Crow-AMSAA Plots to Assess Mishap Trends
Crow-AMSAA (CA) plots are used to model reliability growth. Use of CA plots has expanded into other areas, such as tracking events of interest to management, maintenance problems, and safety mishaps. Safety mishaps can often be successfully modeled using a Poisson probability distribution. CA plots show a Poisson process in log-log space. If the safety mishaps are a stable homogenous Poisson process, a linear fit to the points in a CA plot will have a slope of one. Slopes of greater than one indicate a nonhomogenous Poisson process, with increasing occurrence. Slopes of less than one indicate a nonhomogenous Poisson process, with decreasing occurrence. Changes in slope, known as "cusps," indicate a change in process, which could be an improvement or a degradation. After presenting the CA conceptual framework, examples are given of trending slips, trips and falls, and ergonomic incidents at NASA (from Agency-level data). Crow-AMSAA plotting is a robust tool for trending safety mishaps that can provide insight into safety performance over time
Constitutionality of Mandatory Farmer-Lender Mediation: The Minnesota Plan - Laue v. Production Credit Association, The
In March of 1986, the Minnesota legislature adopted an omnibus farm bill. A principal part of this bill was the Farmer-Lender Mediation Act s (hereinafter Act). The Act requires mandatory mediation notice in the case of any debt foreclosure proceedings brought against farm debtors.8 The Act was scrutinized by the Minnesota Court of Appeals in a case of first impression in Laue v. Production Credit Association
A novel dynamic asset allocation system using Feature Saliency Hidden Markov models for smart beta investing
The financial crisis of 2008 generated interest in more transparent,
rules-based strategies for portfolio construction, with Smart beta strategies
emerging as a trend among institutional investors. While they perform well in
the long run, these strategies often suffer from severe short-term drawdown
(peak-to-trough decline) with fluctuating performance across cycles. To address
cyclicality and underperformance, we build a dynamic asset allocation system
using Hidden Markov Models (HMMs). We test our system across multiple
combinations of smart beta strategies and the resulting portfolios show an
improvement in risk-adjusted returns, especially on more return oriented
portfolios (up to 50 in excess of market annually). In addition, we propose
a novel smart beta allocation system based on the Feature Saliency HMM (FSHMM)
algorithm that performs feature selection simultaneously with the training of
the HMM, to improve regime identification. We evaluate our systematic trading
system with real life assets using MSCI indices; further, the results (up to
60 in excess of market annually) show model performance improvement with
respect to portfolios built using full feature HMMs
Lateral Control in a Driving Simulator: Correlations with Neuropsychological Tests and On-Road Safety Errors
Driving simulators provide precise information on vehicular position at high capture rates. To analyze such data, we have previously proposed a time series model that reduces lateral position data into several parameters for measuring lateral control, and have shown that these parameters can detect differences between neurologically impaired and healthy drivers (Dawson et al, 2010a). In this paper, we focus on the “re-centering” parameter of this model, and test whether the parameter estimates are associated with off-road neuropsychological tests and/or with on-road safety errors. We assessed such correlations in 127 neurologically healthy drivers, ages 40 to 89. We found that our re-centering parameter had significant correlations with five neuropsychological tests: Judgment of Line Orientation (r = 0.38), Block Design (r = 0.27), Contrast Sensitivity (r = 0.31), Near Visual Acuity (r = -0.26), and Grooved Pegboard (r = -0.25). We also found that our re-centering parameter was associated with on-road safety errors at stop signs (r = -0.34) and on-road safety errors during turns (r = -0.22). These results suggest that our re-centering parameter may be a useful tool for measuring and monitoring ability to maintain vehicular lateral control. As GPS-based technology continues to improve in precision and reliability to measure vehicular positioning, our time-series model may potentially be applied as an automated index of driver performance in real world settings that is sensitive to cognitive decline. This work was supported by NIH/NIA awards AG17177, AG15071, and NS044930, and by a scholarship from Nissan Motor Company
Experimental Spinal Fusion With Recombinant Human Bone Morphogenetic Protein-2 Without Decortication of Osseous Elements
Study Design. L4-L5 intertransverse process fusions were produced with 58 μg, 230 μg, or 920 μg of recombinant human bone morphogenetic protein-2 in 20 dogs. Eleven had traditional decortication of posterior elements before insertion of the implant. Nine were left undecorticated. All animals were evaluated 3 months after surgery.
Objectives. To determine whether decortication is a prerequisite for successful fusion in the presence of osteoinductive proteins such as bone morphogenetic protein-2.
Summary of Background Data. Recombinant osteoinductive proteins can induce de novo bone in ectopic soft-tissue sites in the absence of bone marrow elements. Traditional methods for achieving spinal fusion rely on exposure of bone marrow through decortication to facilitate osteogenesis. It is hypothesized that the presence of an implanted osteoinductive protein obviates the need for exposure and release of host inductive factors.
Methods. Recombinant human bone morphogenetic protein-2-induced intertransverse process fusions were performed with and without decortication. Fusion sites were evaluated by computed tomography imaging, high-resolution radiography, manual testing, mechanical testing, and histologic analysis.
Results. One hundred percent of decorticated spines and 89% of undecorticated spines were clinically fused by 3 months. Ninety-one percent of decorticated spines and 78% of undecorticated specimens exhibited bilateral transverse process osseous bridging. The only spines that failed to achieve solid bilateral arthrodesis were in the lowest dose group. With the higher two doses, there was histologic evidence of osseous continuity between the fusion mass and undecorticated transverse processes.
Conclusions. There were no statistical differences in clinical and radiographic fusion rates between decorticated and undecorticated sites. With higher doses of recombinant human bone morphogenetic protein-2, there was little histologic distinction between fusions in decorticated versus undecorticated spines
Metal Promoted Reactions. I. Reactions of 1,2,3-Thiadiazole. II. Oxidation of Oximes by Copper Salts
Chemistr
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