4 research outputs found

    Pengaruh Pemberian Serum Albumin Manusia terhadap Kadar Albumin dalam Darah pada Anjing dengan status Hipoalbuminemia

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    Albumin consists of 50% of the total plasma protein and it is very important protein in the animal's body. Hypoalbuminemia can occurs due to various conditions, such as loss of protein nephropathy, loss of enteropathic proteins, chronic and acute diarrhea or heavy bleeding as well as malnutrition and malabsorption conditions. This study aims to determine the effect of  human serum albumin  20% infusion to increase albumin blood level in hypoalbuminemia dogs. Animals used in this study were 5 dogs whose results showed the levels of albumin below normal limits or hypoalbuminemia. Dogs with hypoalbuminemia will be infused with human serum albumin (HSA) 20% through intravenous for ± 4 hours. Then, these dogs blood will be drawn days after infusion to screen for albumin levels. The results obtained in the form of examination data of albumin blood levels in the blood before and after infusion will be analyzed with paired T-test. The results showed an increase of albumin level significantly from an average of 1.98 ± 0.356 to 2.28 ± 0.257(P <0.05). This study shows the presence of human albumin serum through intravenous infusion was able to increase albumin levels in dogs with hypoalbuminemia

    Identification and Prevalence of Aspergillus sp Isolated from Bali Dog’s Skin

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    Aspergillus sp are fungi that commonly caused a systemic respiratory infection in Human and Dog. In Bali, most of the dog are free-roaming dogs, and has poor skin health condition. Some of them are suspected with fungal infection. Aspergillus sp &nbsp;has high risk to infect the dog, because they are available everywhere in environment. Therefore, this research is conducted for adding primary data of Aspergillus sp isolated from dog’s skin and their prevalence. The samples are 15 free-roaming Bali dogs with suspected fungal infection. Identification was carried out by using microscopic and macroscopic observation methods, skin swab was taken from the dog’s skin using the Mackenzie method, and the sterile toothbrush swab gently from the dog’s skin to the Sabouraud Dextrose Agar (SDA) media. The fungi were cultured on SDA media for macroscopic identification for approximately 3-4 days, mostly to observe how the fungal colony grew and its color. Microscopic identification are using adhesive tape, the tape was gently pressed into the fungal colony, the tape was stuck into the surface of object-glass with 3-4 drops of Methylene Blue staining, and the object glass was examined by using a light microscope, the findings of Aspergillus sp fungi are recorded and the data are descriptively presented. The result shows that most Aspergillus species that were found is Aspergillus fumigatus and Aspergillus niger according to their colonies growth and microscopic appearance, and the prevalence from 15 samples were 53.33%.&nbsp; &nbsp; Keywords: Aspergillus sp, fungi, Bali Dogs, Identification, Prevalenc

    Reaksi Transfusi pada Kucing Hipoalbuminemia yang Diinfus dengan Human Serum Albumin 20%

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    Hipoalbuminemia umum terjadi pada hewan sakit yang dapat memperburuk kesembuhan beberapa penyakit karena berkorelasi dengan peningkatan morbiditas dan mortalitas. Infus human serum albumin 20% digunakan sebagai terapi suportif pada kasus hipoalbuminemia. Penelitian ini bertujuan untuk mengetahui reaksi transfusi yang dihasilkan pada kucing hipoalbuminemia yang diinfus human serum albumin 20% berdasarkan hasil pemeriksaan fisik dan pengamatan tanda klinis. Hewan yang digunakan dalam penelitian ini adalah kucing berbagai ras, dewasa umur 1-3 tahun, jantan maupun betina dengan kondisi hipoalbuminemia. Dilakukan pengambilan darah sebelum terapi dan penghitungan defisit kadar albumin. Larutan human serum albumin 20% diberikan melalui infus intravena dengan dosis tunggal selama 4-5 jam. Volume albumin yang diberikan dihitung menggunakan modifikasi rumus dan metode Hackner. Data hasil pengamatan reaksi transfusi yang dihasilkan pada kucing hipoalbuminemia dianalisis secara deskriptif. Pada kucing terjadi reaksi transfusi segera yang meliputi terjadinya peningkatan suhu rektal, aritmia jantung, ritme napas ireguler, tremor, dan kelemahan, yang umumnya teramati pada 1 jam pertama selama infus. Sementara itu, reaksi transfusi tertunda meliputi penurunan nafsu makan, kelemahan, edema perifer, erithema, kepincangan, ultikaria, lesi kulit, diare, dan inflamasi perivaskuler. Penelitian ini menunjukkan bahwa aplikasi infus human serum albumin 20% menghasilkan reaksi transfusi segera maupun tertunda yang teramati pada 8 ekor kucing. Tidak ditemui adanya reaksi merugikan yang parah selama aplikasi infus human serum albumin 20%

    Laporan Kasus: Anemia pada Anjing Pascaenterektomi

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    Anemia adalah terjadinya defisiensi eritrosit atau hemoglobin atau keduanya hingga kemampuan darah mengangkut oksigen berkurang dan sering dijumpai pada anjing. Anjing lokal  betina bernama Pogan berumur 1 tahun dengan riwayat enterektomi diperiksa dengan keluhan; lemas, kurus, nafsu makan dan minum menurun. Hasil pemeriksaan fisik;  mukosa mulut dan mata anemis, dehidrasi dan kurus. Hasil pemeriksaan hematologi rutin, total protein plasma (TPP) dan albumin menunjukkan bahwa anjing mengalami anemia mikrositik hipokromik, trombositopenia, limfositosis, terjadi penurunan nilai TPP dan hipoalbuminemia. Berdasarkan anamnesa, pemeriksaan fisik dan laboratorik anjing Pogan didiagnosis menderita anemia mikrositik hipokromik yang diakibatkan oleh defisiensi zat besi (Fe). Pengobatan dengan menggunakan preparat Fe dengan dosis 1 ml/5kgbb, subcutan selama 5 hari dan terapi suportif berupa infus serum albumin manusia dengan total volume 128 ml melalui infus intravena selama ±4 jam dan Livron (Vitamin B complex) 1tab/hari, per oral selama 5 hari memberikan hasil yang baik
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