Jesus the Christ as Creator and Redeemer: A Study of the Motive for the Incarceration

The general thrust of contemporary christological investigation is the existential concern of who is Christ? what is his place...in the world, in creation, in life? Many theologians are no longer content with the Patristic and Conciliar language and thought patterns. They see those formulae as limiting discussion on the topic. Earlier generations of theologians, on the other hand, saw them as a source for new questions and insights about who Christ is. The thirteenth-century debate on whether, if mankind had not sinned, Christ would have become incarnate, arising out of their consideration of the implications of the Nicene and Chalcedonian definitions, may seem sterile 1 to some theologians today, but it is the basis for future theological development on the primacy of Christ

Archaeological Excavations at 18AP44: 193 Main Street, Annapolis, Maryland, 1985-1987

193 Main Street (18AP44) is located between Main Street and Duke of Gloucester Street. The property was used ass a yard related to residential and commercial buildings during the 18th and 19th centuries. In the 1930's a movie theatre and parking lot were built on the property. That structure was torn down in the 1980's and a three-story commercial building was constructed. Archaeological excavations were conducted on the property from 1985-1987. A preliminary report was written in 1986 by Paul A. Shackel. This report is the final report on the archaeological investigations at 193 Main Street

Impact of Adiponectin Deficiency on Pulmonary Responses to Acute Ozone Exposure in Mice

Obese mice have increased responses to acute ozone (O3) exposure. T-cadherin is a binding protein for the high–molecular weight isoforms of adiponectin, an anti-inflammatory hormone that declines in obesity. The objective of the present study was to determine whether adiponectin affects pulmonary responses to O3, and whether these effects are mediated through T-cadherin. We performed bronchoalveolar lavage (BAL) and measured pulmonary responsiveness to methacholine after acute air or O3 exposure (2 ppm for 3 h) in adiponectin-deficient (Adipo−/−) or T-cadherin–deficient (T-Cad−/−) mice. O3 increased pulmonary responses to methacholine and increased BAL neutrophils and protein to a greater extent in wild-type than in Adipo−/− mice, whereas T-cadherin deficiency had no effect. O3-induced increases in BAL IL-6 and keratinocyte-derived chemokine (KC), which contribute to O3-induced pulmonary neutrophilia, were also greater in wild-type than in Adipo−/− mice. In contrast, responses to O3 were not altered by transgenic overexpression of adiponectin. To determine which adiponectin isoforms are present in the lung, Western blotting was performed. The hexameric isoform of adiponectin dominated in serum, whereas BAL was dominated by the high–molecular weight isoform of adiponectin. Interestingly, serum adiponectin was greater in T-Cad−/− versus wild-type mice, whereas BAL adiponectin was lower in T-Cad−/− versus wild-type mice, suggesting that T-cadherin may be important for transit of high–molecular weight adiponectin from the blood to the lung. Our results indicate that adiponectin deficiency inhibits pulmonary inflammation induced by acute O3 exposure, and that T-cadherin does not mediate the effects of adiponectin responsible for these events