Green Synthesis, Characterization and Evaluation of Biological Activities of Ag-Mno Nanocomposites from Cyttaranthus Congolensis.

This study consists of biogenic synthesis of Ag-MnO nanocomposite whose aqueous extract from Cyttaranthus congolensis was used as a reducer and stabilizer. The characterization of these particles by visible UV spectroscopy made it possible to identify the band linked to the surface plasmon resonance located around 380 nm. X-ray Diffraction and Fluorescence made it possible to determine the presence of particles of formula Ag 0.21 Mn 0.28 O having crystallized in a Monoclinic system (a= 5.8517 , b = 3.4674 , c = 5.4838  and β = 107.663°). A spherical morphology was determined by Scanning Electron Microscopy (SEM). The haemolytic activity carried out on human blood made it possible to conclude that Ag-MnO nanocomposites are not toxic to human blood. Moreover, these particles showed good antibacterial activity against gram-positive and gram-negative strains of bacteria. Promising results on anthelminthic activity of Ag-MnO nanocomposites against several pathogenic helmints were reported in this study. Besides antibacterial and antihelmintic activities, Ag-MnO nanocomposites also exhibited good anti-inflammatory and antioxidant activity