No evidence for a `redshift cut-off' for the most powerful classical double radio sources

We use three samples (3CRR, 6CE and 6C*) to investigate the radio luminosity function (RLF) for the `most powerful' low-frequency selected radio sources. We find that the data are well fitted by a model with a constant co-moving space density at high redshift as well as by one with a declining co-moving space density above some particular redshift. This behaviour is very similar to that inferred for steep-spectrum radio quasars by Willott et al (1998) in line with the expectations of Unified Schemes. We conclude that there is as yet no evidence for a `redshift cut-off' in the co-moving space densities of powerful classical double radio sources, and rule out a cut-off at z < 2.5.Comment: To appear in `The Hy-redshift universe: Galaxy formation and evolution at high redshift' eds. A.J. Bunker and W.J.M. van Breuge

Functional genomics and rheumatoid arthritis: where have we been and where should we go?

Studies in model organisms and humans have begun to reveal the complexity of the transcriptome. In addition to serving as passive templates from which genes are translated, RNA molecules are active, functional elements of the cell whose products can detect, interact with, and modify other transcripts. Gene expression profiling is the method most commonly used thus far to enrich our understanding of the molecular basis of rheumatoid arthritis in adults and juvenile idiopathic arthritis in children. The feasibility of this approach for patient classification (for example, active versus inactive disease, disease subsets) and improving prognosis (for example, response to therapy) has been demonstrated over the past 7 years. Mechanistic understanding of disease-related differences in gene expression must be interpreted in the context of interactions with transcriptional regulatory molecules and epigenetic alterations of the genome. Ongoing work regarding such functional complexities in the human genome will likely bring both insight and surprise to our understanding of rheumatoid arthritis

Stubble retention and leaf disease in lupin and cereal crops

Retention of cereal stubbles can reduce leaf disease in lupins but increase leaf disease in cereals. The extent of cereal disease carry-over in stubbles depends on the locality and whether multiple cropping or crop rotation is practise

Direct Detection of Products from the Pyrolysis of 2-Phenethyl Phenyl Ether

The pyrolysis of 2-phenethyl phenyl ether (PPE, C_6H_5C_2H_4OC_6H_5) in a hyperthermal nozzle (300-1350 °C) was studied to determine the importance of concerted and homolytic unimolecular decomposition pathways. Short residence times (<100 μs) and low concentrations in this reactor allowed the direct detection of the initial reaction products from thermolysis. Reactants, radicals, and most products were detected with photoionization (10.5 eV) time-of-flight mass spectrometry (PIMS). Detection of phenoxy radical, cyclopentadienyl radical, benzyl radical, and benzene suggest the formation of product by the homolytic scission of the C_6H_5C_2H_4-OC_6H_5 and C_6H_5CH_2-CH_2OC_6H_5 bonds. The detection of phenol and styrene suggests decomposition by a concerted reaction mechanism. Phenyl ethyl ether (PEE, C_6H_5OC_2H_5) pyrolysis was also studied using PIMS and using cryogenic matrix-isolated infrared spectroscopy (matrix-IR). The results for PEE also indicate the presence of both homolytic bond breaking and concerted decomposition reactions. Quantum mechanical calculations using CBS-QB3 were conducted, and the results were used with transition state theory (TST) to estimate the rate constants for the different reaction pathways. The results are consistent with the experimental measurements and suggest that the concerted retro-ene and Maccoll reactions are dominant at low temperatures (below 1000 °C), whereas the contribution of the C_6H_5C_2H_4-OC_6H_5 homolytic bond scission reaction increases at higher temperatures (above 1000 °C)

Maximum likelihood estimates of pairwise rearrangement distances

Accurate estimation of evolutionary distances between taxa is important for many phylogenetic reconstruction methods. In the case of bacteria, distances can be estimated using a range of different evolutionary models, from single nucleotide polymorphisms to large-scale genome rearrangements. In the case of sequence evolution models (such as the Jukes-Cantor model and associated metric) have been used to correct pairwise distances. Similar correction methods for genome rearrangement processes are required to improve inference. Current attempts at correction fall into 3 categories: Empirical computational studies, Bayesian/MCMC approaches, and combinatorial approaches. Here we introduce a maximum likelihood estimator for the inversion distance between a pair of genomes, using the group-theoretic approach to modelling inversions introduced recently. This MLE functions as a corrected distance: in particular, we show that because of the way sequences of inversions interact with each other, it is quite possible for minimal distance and MLE distance to differently order the distances of two genomes from a third. This has obvious implications for the use of minimal distance in phylogeny reconstruction. The work also tackles the above problem allowing free rotation of the genome. Generally a frame of reference is locked, and all computation made accordingly. This work incorporates the action of the dihedral group so that distance estimates are free from any a priori frame of reference.Comment: 21 pages, 7 figures. To appear in the Journal of Theoretical Biolog

Infrared and millimetre-wavelength evidence for cold accretion within a z = 2.83 Lyman-alpha blob

‘The definitive version is available at www.blackwell-synergy.com.’ Copyright Blackwell Publishing DOI: 10.1111/j.1365-2966.2008.13580.xThis paper discusses infrared and millimetre-wavelength observations of a Lyman alpha blob (LAB) discovered by Smith & Jarvis, a candidate for ionization by the cold accretion scenario discussed in Fardal et al. and Dijkstra et al. We have observed the counterpart galaxy at infrared wavelengths in deep observations with the Spitzer Space Telescope using the IRAC 3.6, 4.5, 5.8 and 8.0 mu m and MIPS 24 mu m bands, as well as using the Max-Planck Millimeter Bolometer (MAMBO-2) at a wavelength of 1.2 mm with the IRAM 30 m telescope. These observations probe the greater than or similar to 95 kpc Lyman alpha halo for the presence of obscured active galactic nucleus (AGN) components or the presence of a violent period of star formation invoked by other models of ionization for these mysterious objects. 24 mu m observations suggest that an obscured AGN would be insufficiently luminous to ionize the halo, and that the star formation rate within the halo may be as low as < 140 M-circle dot yr(-1) depending on the model spectral energy distribution (SED) used. This is reinforced by our observations at 1.2 mm using MAMBO-2, which yield an upper limit of star formation rate < 550 M-circle dot yr(-1) from our non-detection to a 3 sigma flux limit of 0.86 mJy beam(-1). Finding no evidence for either AGN or extensive star formation, we conclude that this halo is ionized by a cold accretion process. We derive model SEDs for the host galaxy, and use the Bruzual & Charlot and Maraston libraries to show that the galaxy is well described by composite stellar populations of total mass 3.42 +/- 0.13 x 10(11) or 4.35 +/- 0.16 x 10(11) M-circle dot depending on the model SEDs used.Peer reviewe

An Application of Multi-band Forced Photometry to One Square Degree of SERVS: Accurate Photometric Redshifts and Implications for Future Science

We apply The Tractor image modeling code to improve upon existing multi-band photometry for the Spitzer Extragalactic Representative Volume Survey (SERVS). SERVS consists of post-cryogenic Spitzer observations at 3.6 and 4.5 micron over five well-studied deep fields spanning 18 square degrees. In concert with data from ground-based near-infrared (NIR) and optical surveys, SERVS aims to provide a census of the properties of massive galaxies out to z ~ 5. To accomplish this, we are using The Tractor to perform "forced photometry." This technique employs prior measurements of source positions and surface brightness profiles from a high-resolution fiducial band from the VISTA Deep Extragalactic Observations (VIDEO) survey to model and fit the fluxes at lower-resolution bands. We discuss our implementation of The Tractor over a square degree test region within the XMM-LSS field with deep imaging in 12 NIR/optical bands. Our new multi-band source catalogs offer a number of advantages over traditional position-matched catalogs, including 1) consistent source cross-identification between bands, 2) de-blending of sources that are clearly resolved in the fiducial band but blended in the lower-resolution SERVS data, 3) a higher source detection fraction in each band, 4) a larger number of candidate galaxies in the redshift range 5 < z < 6, and 5) a statistically significant improvement in the photometric redshift accuracy as evidenced by the significant decrease in the fraction of outliers compared to spectroscopic redshifts. Thus, forced photometry using The Tractor offers a means of improving the accuracy of multi-band extragalactic surveys designed for galaxy evolution studies. We will extend our application of this technique to the full SERVS footprint in the future.Comment: accepted to ApJ, 22 pages, 12 figure