250 research outputs found

    Mutation du foncier agricole en frange urbaine : élaboration et mise à l'épreuve d'une politique de régulation territoriale

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    International audienceLe pôle urbain de Montpellier s'est largement étalé lors des dernières décennies à la faveur de son dynamisme démographique et du retrait de la viticulture : la " maîtrise " communale de l'urbanisme s'est traduite par une urbanisation tous azimuts. Comment mettre fin à ces processus sans compromettre l'économie résidentielle ? C'est une priorité de la nouvelle intercommunalité dont la politique d'aménagement est analysée. La genèse de cette politique est retracée ainsi que sa traduction dans le schéma de cohérence territoriale, dont les objectifs d'économie d'espace et les outils - identification des limites, densification, maîtrise foncière - sont détaillés. Sa mise en ½uvre au niveau communal révèle les forces et les faiblesses de cette politique. Cette étude empirique soutient une réflexion plus générale sur les dynamiques foncières périurbaines et les outils politiques de régulation, à la croisée des problématiques de gouvernance territoriale et de préservation des ressources

    Polarization-analyzed resonant inelastic x-ray scattering of the orbital excitations in KCuF3

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    We report a Cu K-edge resonant inelastic x-ray scattering (RIXS) study of orbital excitations in KCuF3 . By performing the polarization analysis of the scattered photons, we disclose that the excitation between the eg orbitals and the excitations from t2g to eg exhibit distinct polarization dependence. The polarization dependence of the respective excitations is interpreted based on a phenomenological consideration of the symmetry of the RIXS process that yields a necessary condition for observing the excitations. In addition, we show that the orbital excitations are dispersionless within our experimental resolution.Comment: 5 pages, 3 figure

    Characterization of diamagnetism inside an ECR thruster with a diamagnetic loop

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    The plasma-induced magnetic field in an electron cyclotron resonance plasma thruster is measured non-intrusively by means of a diamagnetic loop that encloses the plasma flow. The calibration process is described, and parasitic currents in the thruster walls and plasma oscillations are identified as the dominant sources of uncertainty. The integrated magnetic flux is seen to depend on the applied power and less significantly on the mass flow rate. The effect of the diamagnetic loop radius is also studied by testing two loops of different diameters. To estimate the perpendicular electron pressure in the plasma from the loop measurements, two plasma beam models, 1D and 2D, are used. While both models give similar results for the small loop, they differ significantly for the large loop, showing the relevance of 2D effects when a large diamagnetic loop is used.This work was made in the framework of project MINOTOR that has received funding from the European Union's Horizon 2020 research and innovation program under Grant agreement No 730028. Additional funding came from the Spanish R&D National Plan (Grant No. PN ESP2016-75887)

    Resonant inelastic x-ray scattering in electronically quasi-zero-dimensional CuB2O4

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    We explore the general phenomenology of resonant inelastic scattering (RIXS) using CuB2O4, a network of CuO4 plaquettes electronically isolated by B+3 ions. Spectra show a small number of well-separated features, and we exploit the simple electronic structure to explore RIXS phenomenology by developing a calculation which allows for intermediate-state effects ignored in standard approaches. These effects are found to be non-negligible and good correspondence between our model and experiment leads to a simple picture of such phenomenology as the genesis of d-d excitations at the K edge and intermediate-state interference effects.Comment: Phys. Rev. B 80, 092509 (2009

    Preclinical Evaluation of a Lentiviral Vector for Huntingtin Silencing.

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    Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder resulting from a polyglutamine expansion in the huntingtin (HTT) protein. There is currently no cure for this disease, but recent studies suggest that RNAi to downregulate the expression of both normal and mutant HTT is a promising therapeutic approach. We previously developed a small hairpin RNA (shRNA), vectorized in an HIV-1-derived lentiviral vector (LV), that reduced pathology in an HD rodent model. Here, we modified this vector for preclinical development by using a tat-independent third-generation LV (pCCL) backbone and removing the original reporter genes. We demonstrate that this novel vector efficiently downregulated HTT expression in vitro in striatal neurons derived from induced pluripotent stem cells (iPSCs) of HD patients. It reduced two major pathological HD hallmarks while triggering a minimal inflammatory response, up to 6 weeks after injection, when administered by stereotaxic surgery in the striatum of an in vivo rodent HD model. Further assessment of this shRNA vector in vitro showed proper processing by the endogenous silencing machinery, and we analyzed gene expression changes to identify potential off-targets. These preclinical data suggest that this new shRNA vector fulfills primary biosafety and efficiency requirements for further development in the clinic as a cure for HD

    Investigation of the thermal stability of Mg/Co periodic multilayers for EUV applications

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    We present the results of the characterization of Mg/Co periodic multilayers and their thermal stability for the EUV range. The annealing study is performed up to a temperature of 400\degree C. Images obtained by scanning transmission electron microscopy and electron energy loss spectroscopy clearly show the good quality of the multilayer structure. The measurements of the EUV reflectivity around 25 nm (~49 eV) indicate that the reflectivity decreases when the annealing temperature increases above 300\degreeC. X-ray emission spectroscopy is performed to determine the chemical state of the Mg atoms within the Mg/Co multilayer. Nuclear magnetic resonance used to determine the chemical state of the Co atoms and scanning electron microscopy images of cross sections of the Mg/Co multilayers reveal changes in the morphology of the stack from an annealing temperature of 305\degreee;C. This explains the observed reflectivity loss.Comment: Published in Applied Physics A: Materials Science \& Processing Published at http://www.springerlink.com.chimie.gate.inist.fr/content/6v396j6m56771r61/ 21 page
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