Selective Laser Melting Strategy for Fabrication of Thin Struts Usable in Lattice Structures

This paper deals with the selective laser melting (SLM) processing strategy for strut-lattice structure production which uses only contour lines and allows the porosity and roughness level to be managed based on ombination of the input and linear energy parameters

How many species of whipworms do we share? Whipworms from man and other primates form two phylogenetic lineages

The whipworms, i.e. parasitic nematodes of the genus Trichuris Roederer, 1761, infect a variety of mammals. Apparently low diversity of primate-infecting species of Trichuris strongly contrasts with the high number of species described in other mammalian hosts. The present study addresses the diversity of whipworms in captive and free-ranging primates and humans by analysing nuclear (18S rRNA, ITS2) and mitochondrial (cox1) DNA. Phylogenetic analyses revealed that primate whipworms form two independent lineages: (i) the Trichuris trichiura (Linnaeus, 1771) clade comprised of genetically almost identical whipworms from human and other primates, which suggests the ability of T. trichiura to infect a broader range of primates; (ii) a clade containing primarily Trichuris suis Schrank, 1788, where isolates from human and various primates formed a sister group to isolates from pigs; the former isolates thus may represent of more species of Trichuris in primates including humans. The analysis of cox1 has shown the polyphyly of the genera Trichuris and Capillaria, Zeder, 1800. High sequence similarity of the T. trichiura isolates from humans and other primates suggests their zoonotic potential, although the extent of transmission between human and other non‐human primates remains questionable and requires further stud

Materiálová a rozměrová analýza bimetalového trubkového oblouku s definovanými poloměry ohybu

This paper deals with material and dimensional bending analysis of bimetallic pipes with defined bending radii. Basic characteristics of selected nickel superalloys with analysis of Inconel 625 and 16Mo3 steel in terms of primary mechanical properties and chemical composition are presented. The practical part where the bimetallic tube is analyzed in terms of material properties is also performed geometric dimensional analysis, for which test specimens with different bending radii are made.Předložený příspěvek se zabývá materiálovou a rozměrovou analýzou bimetalového trubkového oblouku s definovanými poloměry ohybu. Teoretická část příspěvku byla zaměřena na základní charakteristiku vybraných niklových superslitin s rozborem materiálu Inconel 625 a oceli 16Mo3 z pohledu primárních mechanických vlastností a chemického složení. Praktická část příspěvku charakterizuje bimetalový trubkový oblouk s prodlouženými konci s ohybem 1D z hlediska materiálových analýz, zejména analýzy chemického složení, struktury materiálů, mikrotvrdosti a přítomnosti trhlin

Analysis of the OCHN3MFA steel in terms of cutting forces and cutting material flank wear mechanisms in hard turning processes

This article deals with the effect of selected machining parameter values in hard turning of tested OCHN3MFA steel in terms of SEM microstructural analysis of workpiece material, cutting forces, long-term tests, and SEM observations of flank wear VB and crater wear KT of used changeable coated cemented carbide cutting inserts in the processes of performed experiments. OCHN3MFA steel was selected as an experimental (workpiece) material. The selected experimental steel was analyzed prior to hard turning tests to check the initial microstructure of bulk material and subsurface microstructure after hard turning and chemical composition. Study of workpiece material’s microstructure and worn cemented carbide cutting inserts was performed with Tescan Vega TS 5135 scanning electron microscope (SEM) with the X-Ray microanalyzer Noran Six/300. The chemical composition of workpiece material was analyzed with Tasman Q4 surface analyzer. All hard turning experiments of the used specimens were performed under the selected machining parameters in the SU 50A machine tool with the 8th selected individual geometry of coated cementite carbide cutting inserts clamped in the appropriate DCLNR 2525M12-M type of cutting tool holder. During the hard turning technological process of the individual tested samples made of OCHN3MFA steel, cutting forces were measured with a Kistler 9257B piezoelectric dynamometer, with their subsequent evaluation using Dynoware software. After the long-term testing, other experiments and results were also realized, evaluating the influence of selected machining parameters with different cutting insert geometry on the achieved surface quality

DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome

Organ function depends on tissues adopting the correct architecture. However, insights into organ architecture are currently hampered by an absence of standardized quantitative 3D analysis. We aimed to develop a robust technology to visualize, digitalize, and segment the architecture of two tubular systems in 3D: double resin casting micro computed tomography (DUCT). As proof of principle, we applied DUCT to a mouse model for Alagille syndrome (Jag1Ndr/Ndr mice), characterized by intrahepatic bile duct paucity, that can spontaneously generate a biliary system in adulthood. DUCT identified increased central biliary branching and peripheral bile duct tortuosity as two compensatory processes occurring in distinct regions of Jag1Ndr/Ndr liver, leading to full reconstitution of wild-type biliary volume and phenotypic recovery. DUCT is thus a powerful new technology for 3D analysis, which can reveal novel phenotypes and provide a standardized method of defining liver architecture in mouse models