1,413 research outputs found

    Latest news from the HAWC outrigger array

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    The High Altitude Water Cherenkov (HAWC) observatory is a very high energy gamma-ray detector located in Mexico. In late 2018, the HAWC collaboration completed a major upgrade consisting of the addition of a sparse outrigger array of 345 small water Cherenkov detectors (WCDs) surrounding the 300 WCDs of the main array and extending the instrumented area by a factor of 4. It provides an improved reconstruction of the showers whose core and footprint are not well contained in the array and increases the effective area in the range of a few TeV to beyond 100 TeV. This improvement in sensitivity will help to have a better understanding of the Galactic sources that accelerate particles up to the knee of the cosmic ray spectrum. In this contribution, we will show the current status, the performance, and the first results from the HAWC outrigger array

    The acceleration and storage of radioactive ions for a neutrino factory

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    The term beta-beam has been coined for the production of a pure beam of electron neutrinos or their antiparticles through the decay of radioactive ions circulating in a storage ring. This concept requires radioactive ions to be accelerated to a Lorentz gamma of 150 for 6He and 60 for 18Ne. The neutrino source itself consists of a storage ring for this energy range, with long straight sections in line with the experiment(s). Such a decay ring does not exist at CERN today, nor does a high-intensity proton source for the production of the radioactive ions. Nevertheless, the existing CERN accelerator infrastructure could be used as this would still represent an important saving for a beta-beam facility. This paper outlines the first study, while some of the more speculative ideas will need further investigations.Comment: Accepted for publication in proceedings of Nufact02, London, 200

    Distributed forcing of the flow past a blunt-based axisymmetric bluff body

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    In this paper we address the influence of a blowing/suction-type distributed forcing on the flow past a blunt-based axisymmetric bluff body by means of direct numerical simulations. The forcing is applied via consecutive blowing and suction slots azimuthally distributed along the trailing edge of the bluff body. We examine the impact of the forcing wavelength, amplitude and waveform on the drag experienced by the bluff body and on the occurrence of the reflectional symmetry preserving (RSP) and reflectional symmetry breaking (RSB) wake modes, for Reynolds numbers 800 and 1000. We show that forcing the flow at wavelengths inherent to the unforced flow drastically damps drag oscillations associated with the vortex shedding and vorticity bursts, up to their complete suppression. The overall parameter analysis suggests that this damping results from the surplus of streamwise vorticity provided by the forcing, that tends to stabilize the ternary vorticity lobes observed at the aft part of the bluff body. In addition, conversely to a blowing-type or suction-type forcing, the blowing/suction-type forcing involves strong nonlinear interactions between locally decelerated and accelerated regions, severely affecting both the mean drag and the frequencies representative of the vortex shedding and vorticity bursts

    A 57-year-old man who developed arthritis during R-CHOP chemotherapy for non-Hodgkin lymphoma

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    Rituximab is a chimeric human-mouse anti-CD20 monoclonal antibody, which is used in the treatment of both B-cell lymphomas and rheumatic diseases. We describe a case of a previously healthy 57-year-old man developing arthritis while being treated with rituximab-CHOP chemotherapy (R-CHOP) for a non-Hodgkin lymphoma. The remittant arthritis developed at successively shorter time-intervals after R-CHOP administration and only improved after rituximab was removed from the chemotherapy schedule, suggesting a rituximab-related phenomenon, as extensive diagnostic testing ruled out any other diagnosis

    Border skirmishes and the question of belonging: An authoethnographic account of everyday exclusion in multicultural society

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    Transnational migration has transformed most European countries, making the problem of how to 'integrate' an increasingly popular topic in public debates and social policy. It is assumed that as long as the newcomer learns the language, adapts to the local customs and finds work, s/he will be integrated and welcomed with open arms as a full-fledged member of society. Based on an autoethnography of our experiences as US-born, long-term and fully 'integrated' residents of the Netherlands, one of Europe's most multicultural societies, we have explored some of the subtle, well-intentioned practices of distancing and exclusion that are part of the fabric of everyday life. We will show how, contrary to the official discourse of integration, 'Dutch-ness' as a white/ethnic national identity is continuously constructed as a 'we', which excludes all 'others'. And, indeed, we have discovered that, paradoxically, the closer the 'other' comes to being completely assimilated into Dutch society, the more the symbolic borders of national belonging may need to be policed and tightened. © The Author(s) 2011

    Respiratory Physiology and the Impact of Different Modes of Ventilation on the Photoplethysmographic Waveform

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    The photoplethysmographic waveform sits at the core of the most used, and arguably the most important, clinical monitor, the pulse oximeter. Interestingly, the pulse oximeter was discovered while examining an artifact during the development of a noninvasive cardiac output monitor. This article will explore the response of the pulse oximeter waveform to various modes of ventilation. Modern digital signal processing is allowing for a re-examination of this ubiquitous signal. The effect of ventilation on the photoplethysmographic waveform has long been thought of as a source of artifact. The primary goal of this article is to improve the understanding of the underlying physiology responsible for the observed phenomena, thereby encouraging the utilization of this understanding to develop new methods of patient monitoring. The reader will be presented with a review of respiratory physiology followed by numerous examples of the impact of ventilation on the photoplethysmographic waveform
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