Collaborating with Businesses to Support and Sustain Research

Financial assistance is necessary for sustaining research at universities. Business collaborations are a potential means for obtaining these funds. To secure funding, understanding the process for obtaining these business funds is important for nursing faculty members. Although faculty rarely request funding from businesses, they are often in a position to solicit financial support due to existing relationships with clinical agency administrators, staff, and community leaders. The economic support received from businesses provides outcomes in nursing research, research education, academic–service partnerships, and client health care. This article describes the steps and processes involved in successfully obtaining research funding from businesses. In addition, case examples for securing and maintaining funding from health care agencies (evidence-based practice services) and from a health manufacturing company (product evaluation) are used to demonstrate the process

Translation initiation factor eIF3 promotes programmed stop codon readthrough.

Programmed stop codon readthrough is a post-transcription regulatory mechanism specifically increasing proteome diversity by creating a pool of C-terminally extended proteins. During this process, the stop codon is decoded as a sense codon by a near-cognate tRNA, which programs the ribosome to continue elongation. The efficiency of competition for the stop codon between release factors (eRFs) and near-cognate tRNAs is largely dependent on its nucleotide context; however, the molecular mechanism underlying this process is unknown. Here, we show that it is the translation initiation (not termination) factor, namely eIF3, which critically promotes programmed readthrough on all three stop codons. In order to do so, eIF3 must associate with pre-termination complexes where it interferes with the eRF1 decoding of the third/wobble position of the stop codon set in the unfavorable termination context, thus allowing incorporation of near-cognate tRNAs with a mismatch at the same position. We clearly demonstrate that efficient readthrough is enabled by near-cognate tRNAs with a mismatch only at the third/wobble position. Importantly, the eIF3 role in programmed readthrough is conserved between yeast and humans

Key to Florida Alydidae (Hemiptera: Heteroptera) and selected exotic pest species

A key to the fourteen native Florida species and seven exotic pest species of Alydidae is presented here. The key uses external, non-genitalic morphology and allows for rapid separation of the native species and exotic pests included herein

Science on a Shoestring: Building Nursing Knowledge With Limited Funding

Building the science for nursing practice has never been more important. However, shrunken federal and state research budgets mean that investigators must find alternative sources of financial support and develop projects that are less costly to carry out. New investigators often build beginning programs of research with limited funding. This article provides an overview of some cost-effective research approaches and gives suggestions for finding other sources of funding. Examples of more cost-effective research approaches include adding complementary questions to existing funded research projects; conducting primary analysis of electronic patient records and social media content; conducting secondary analysis of data from completed studies; reviewing and synthesizing previously completed research; implementing community-based participatory research; participating in collaborative research efforts such as inter-campus team research, practice-based research networks (PBRNs), and involving undergraduate and doctoral students in research efforts. Instead of relying on funding from the National Institutes of Health (NIH) and other government agencies, nurse researchers may be able to find support for research from local sources such as businesses, organizations, or clinical agencies. Investigators will increasingly have to rely on these and other creative approaches to fund and implement their research programs if granting agency budgets do not significantly expand

Key to Florida Alydidae (Hemiptera: Heteroptera) and selected exotic pest species

A key to the fourteen native Florida species and seven exotic pest species of Alydidae is presented here. The key uses external, non-genitalic morphology and allows for rapid separation of the native species and exotic pests included herein

A diagnostic approach to building collaborative capacity in an interagency context

Federal Acquisition Reform has consistently called for more and better collaboration among participating organizations. Experience shows, however, that inter-organizational collaboration can be difficult at best. Our research focuses on imperatives of successful collaboration and aims to assist organizations in diagnosing their collaborative capacity. Based on prior research with homeland security organizations, we offer a model of inter-organizational collaborative capacity grounded in a systems perspective. We then identify enablers and barriers that contribute to collaborative capacity. A diagnostic process based on the established practices of organization development is offered to guide the design of tailored assessments of collaborative capacity. We present a comprehensive set of both interview and survey questions, based on our model, which can be used in creating a collaborative capacity audit. The ability to diagnose collaborative capacity encourages literacy around collaboration and assists leaders in determining mechanisms for developing their organization's collaborative capacity. Finally, we describe the future plans for validating these assessment tools.-- p. iv.Approved for public release; distribution is unlimited

Eicosanoid Production following One Bout of Exercise in Middle-Aged African American Pre- and Stage 1 Hypertensives

Endothelial dysfunction and a sedentary lifestyle may be involved in the development of hypertension which is proliferative among middle-aged African Americans (AA). Signaling molecules derived from the oxidation of 20-carbon fatty acid molecules known as eicosanoids influence vascular tone. The relationship between aerobic fitness and eicosanoid formation following exercise in middle-aged African American hypertensives is unknown. Purpose. To determine the relationship between aerobic capacity and eicosanoid formation after a bout of moderate-intensity exercise in middle-aged AA hypertensives. Methods. Ten sedentary hypertensive AA underwent 50 min of aerobic exercise at 65% VO2max. Urine was collected for 24 hr on two occasions, prior to testing and immediately following the bout of exercise. Urinary metabolites of prostacyclin (6-keto PGF1α) and thromboxane (11-dTXB2) were measured during the day and night periods by high-performance liquid chromatography (HPLC). Results. 6-keto PGF1α levels significantly increased (P = .04) following the bout of exercise compared to the control day. There was a significant relationship (r = .49, P < .05) between 6-keto PGF1α levels and VO2max during the exercise day. Conclusion. Based on this preliminary study, there appears to be a relationship between aerobic capacity and exercise-induced 6-keto PGF1α production in middle-aged hypertensive AAs. AAs with lower VO2max had lower 6-keto PGF1α formation

Interorganizational collaborative capacity: development of a database to refine instrumentation and explore patterns

Interorganizational collaborative capacity (ICC) is the capability of organizations (or a set of organizations) to enter into, develop, and sustain interorganizational systems in pursuit of collective outcomes. The objectives of the ICC research program are (1) to understand the success factors that lead to and the barriers that interfere with ICC; (2) to construct diagnostic methods and tools to assess these factors; and (3) to develop methods that contribute to the development of ICC in and among agencies and organizations. The research literature indicates that a major barrier blocking progress in understanding ICC is the absence of reliable, valid measures for the construct. This study addresses this problem. It presents the results of ICC scale development using samples of public sector, defense and security professionals from two areas: Homeland Defense and Security and Defense Acquisition and Contracting. The research presents scales that have very good to excellent internal consistency reliability and convergent validity. The report then applies the survey to create a profile and do a summary assessment of a major DoD Acquisition and Contracting organization's ICC. The survey factors are integrated into our ICC open systems model. The value of survey results in developing an organization's (or an organizational set's) current ICC is discussed, as are future research directions.Approved for public release; distribution is unlimited

Balancing Instrumental, Biographic and Social Competencies: Enhancing the Participation of Young Adults in Economic and Social Processes

No abstract available