Eta-nucleon and eta-prime-nucleon coupling constants in QCD and the role of gluons

Coupling constants of $\eta$ and $\eta^{\prime}$ mesons with nucleons have been calculated using the method of QCD sum rules. Starting from vacuum-to-meson correlation function of interpolating fields of two nucleons, its matrix element with respect to nucleon spinors has been considered. Coupling constants at the physical points have been estimated from extrapolation of results obtained at two other points. Anomalous glue has been found to give substantial contribution to the coupling constants and also accounts for a significant OZI-rule violation.Comment: 6 pages, 3 figures and 2 table

Experimental investigation of shock-cell noise reduction for dual-stream nozzles in simulated flight comprehensive data report. Volume 1: Test nozzles and acoustic data

Parameters which contribute to supersonic jet shock noise were investigated for the purpose of determining means to reduce such noise generation to acceptable levels. Six dual-stream test nozzles with varying flow passage and plug closure designs were evaluated under simulated flight conditions in an anechoic chamber. All nozzles had combined convergent-divergent or convergent flow passages. Acoustic behavior as a function of nozzle flow passage geometry was measured. The acoustic data consist primarily of 1/3 octave band sound pressure levels and overall sound pressure levels. Detailed schematics and geometric characteristics of the six scale model nozzle configurations and acoustic test point definitions are presented. Tabulation of aerodynamic test conditions and a computer listing of the measured acoustic data are displayed

Effect of rice husk biochar, carpet waste, farm yard manure and plant growth promoting rhizobium on the growth and yield of rice (Oryza sativa)

The present investigation was aimed for improving growth and yield of crop using waste products of differ-ent activities and also useful in ecological stability of soil environment. This objective is not only an economic option for poor farmer but also an effective strategy for increasing yield. The experiment was conducted in the organic farm-ing plot of the Institute of Agricultural Sciences, BHU, Varanasi during kharif season of rice crop in 2014. The field experiment was laid out in randomized block design (RBD) with 10 treatments and three replications. Application of graded level of biochar, carpet waste farm yard manure (FYM) and plant growth promoting rhizobium (PGPR) was found to significantly enhance the grain and straw yield of rice by 57.70% and 56.08% over control, respectively

Immunoglobulin Allotypes and Immune Response to Meningococcal Group B Polysaccharide

Serum samples were collected from 120 healthy adult volunteers (105 Caucasians and 15 Negros) before and after immunization with meningococcal polysaccharide (MPS) group B vaccine. Antibodies to MPS group B were measured and sera were typed for several Gm and Km(l) allotypes. A significant association was found between the Km(l) allotype and immune response to MPS group B in Caucasians

PRIC295, a Nuclear Receptor Coactivator, Identified from PPARα-Interacting Cofactor Complex

The peroxisome proliferator-activated receptor-α (PPARα) plays a key role in lipid metabolism and energy combustion. Chronic activation of PPARα in rodents leads to the development of hepatocellular carcinomas. The ability of PPARα to induce expression of its target genes depends on Mediator, an evolutionarily conserved complex of cofactors and, in particular, the subunit 1 (Med1) of this complex. Here, we report the identification and characterization of PPARα-interacting cofactor (PRIC)-295 (PRIC295), a novel coactivator protein, and show that it interacts with the Med1 and Med24 subunits of the Mediator complex. PRIC295 contains 10 LXXLL signature motifs that facilitate nuclear receptor binding and interacts with PPARα and five other members of the nuclear receptor superfamily in a ligand-dependent manner. PRIC295 enhances the transactivation function of PPARα, PPARγ, and ERα. These data demonstrate that PRIC295 interacts with nuclear receptors such as PPARα and functions as a transcription coactivator under in vitro conditions and may play an important role in mediating the effects in vivo as a member of the PRIC complex with Med1 and Med24

Experimental investigation of shock-cell noise reduction for single-stream nozzles in simulated flight, comprehensive data report. Volume 1: Test nozzles and acoustic data

The model nozzle configurations, acoustic test conditions, and detailed test results from the hot static and simulated flight acoustic tests at the General Electric Anechoc Chamber are described

A Characterization of the Negative Multinomial Distribution

This paper deals with a characterization of the negative multinomial distribution. It is based on the assumption that the conditional distribution of two random vectors is multivariate inverse hypergeometric. It makes use essentially of a multivariate analogue of a condition known in the literature as the Rao-Rubin condition. The result is extended to include characterizations of truncated forms of the negative multinomial distribution. Comparison with previous results in the field is made and an example is included to demonstrate a possible use of the characterizatio

Landscape Genetics Reveals Focal Transmission of a Human Macroparasite

Macroparasite infections (e.g., helminths) remain a major human health concern. However, assessing transmission dynamics is problematic because the direct observation of macroparasite dispersal among hosts is not possible. We used a novel landscape genetics approach to examine transmission of the human roundworm Ascaris lumbricoides in a small human population in Jiri, Nepal. Unexpectedly, we found significant genetic structuring of parasites, indicating the presence of multiple transmission foci within a small sampling area (∼14 km2). We analyzed several epidemiological variables, and found that transmission is spatially autocorrelated around households and that transmission foci are stable over time despite extensive human movement. These results would not have been obtainable via a traditional epidemiological study based on worm counts alone. Our data refute the assumption that a single host population corresponds to a single parasite transmission unit, an assumption implicit in many classic models of macroparasite transmission. Newer models have shown that the metapopulation-like pattern observed in our data can adversely affect targeted control strategies aimed at community-wide impacts. Furthermore, the observed metapopulation structure and local mating patterns generate an excess of homozygotes that can accelerate the spread of recessive traits such as drug resistance. Our study illustrates how molecular analyses complement traditional epidemiological information in providing a better understanding of parasite transmission. Similar landscape genetic approaches in other macroparasite systems will be warranted if an accurate depiction of the transmission process is to be used to inform effective control strategies

Neuronal expression in Drosophila of an evolutionarily conserved metallophosphodiesterase reveals pleiotropic roles in longevity and odorant response

Evolutionarily conserved genes often play critical roles in organismal physiology. Here, we describe multiple roles of a previously uncharacterized Class III metallophosphodiesterase in Drosophila, an ortholog of the MPPED1 and MPPED2 proteins expressed in the mammalian brain. dMpped, the product of CG16717, hydrolyzed phosphodiester substrates including cAMP and cGMP in a metal-dependent manner. dMpped is expressed during development and in the adult fly. RNA-seq analysis of dMppedKO flies revealed misregulation of innate immune pathways. dMppedKO flies showed a reduced lifespan, which could be restored in Dredd hypomorphs, indicating that excessive production of antimicrobial peptides contributed to reduced longevity. Elevated levels of cAMP and cGMP in the brain of dMppedKO flies was restored on neuronal expression of dMpped, with a concomitant reduction in levels of antimicrobial peptides and restoration of normal life span. We observed that dMpped is expressed in the antennal lobe in the fly brain. dMppedKO flies showed defective specific attractant perception and desiccation sensitivity, correlated with the overexpression of Obp28 and Obp59 in knock-out flies. Importantly, neuronal expression of mammalian MPPED2 restored lifespan in dMppedKO flies. This is the first description of the pleiotropic roles of an evolutionarily conserved metallophosphodiesterase that may moonlight in diverse signaling pathways in an organism