Internet skills performance tests: are people ready for eHealth?

Background:\ud Despite the amount of online health information, there are several barriers that limit the Internet’s adoption as a source of health information. One of these barriers is highlighted in conceptualizations of the digital divide which include the differential possession of Internet skills, or “eHealth literacy”. Most measures of Internet skills among populations at large use self-assessments. The research discussed here applies a multifaceted definition of Internet skills and uses actual performance tests.\ud \ud Objective:\ud The purpose of this study was to assess how ready a sample of the general population is for eHealth. More specifically, four types of Internet skills were measured in a performance test in which subjects had to complete health-related assignments on the Internet.\ud \ud Methods:\ud From November 1, 2009, through February 28, 2010, 88 subjects participated in the study. Subjects were randomly selected from a telephone directory. A selective quota sample was used divided over equal subsamples of gender, age, and education. Each subject had to accomplish assignments on the Internet. The Internet skills accounted for were categorized as operational (basic skills to use the Internet), formal (navigation and orientation), information (finding information), and strategic (using the information for personal benefits). The tests took approximately 1.5 hours and were conducted in a University office, making the setting equally new for all. Successful completion and time spent on the assignments—the two main outcomes—were directly measured by the test leader.\ud \ud Results:\ud The subjects successfully completed an average of 73% (5.8/8) of the operational Internet skill tasks and an average of 73% (2.9/4) of the formal Internet skill tasks. Of the information Internet skills tasks, an average of 50% (1.5/3) was completed successfully and, of the strategic Internet skills tasks, 35% (0.7/2). Only 28% (25/88) of the subjects were able to successfully complete all operational skills tasks, 39% (34/88) all formal skills tasks, 13% (11/88) all information skills tasks, and 20% (18/88) both the strategic skill tasks. The time spent on the assignments varied substantially. Age and education were the most important contributors to the operational and formal Internet skills. Regarding the formal Internet skills, years of Internet experience also had some influence. Educational level of attainment was the most important contributor to the information and strategic Internet skills.\ud \ud Conclusions:\ud Although the amount of online health-related information and services is consistently growing, it appears that the general population lacks the skills to keep up. Most problematic appear to be the lack of information and strategic Internet skills, which, in the context of health, are very important. The lack of these skills is also problematic for members of younger generations, who are often considered skilled Internet users. This primarily seems to account for the operational and formal Internet skills. The results of the study strongly call for policies to increase the level of Internet skills

Investigating outcomes of online engagement

So far, digital divide research and policy was primarily engaged with access to computers and the Internet. The results of having access to these digital media were neglected. This article focuses on the tangible outcomes of online access and activity. There have been few attempts to measure such outcomes. With respect to digital inclusion, the most interesting question is who actually benefits from being online. This article answers this question by the results of a representative survey of the Dutch population in 2013. Internet outcomes and benefits are framed in concepts of participation in several domains of society: economic, social, educational, political and institutional. The results show that the same social categories having more access to the Internet also have more outcomes or benefits from Internet use: people with high education and income and young people. Outcomes in fact are the essence or stake of the digital divide. This study shows that some categories of the Dutch population benefit substantially more than others by using the Internet in finding a job, lower prices of products and services, better opportunities of education, a political party to vote for, new friends, a partner in dating and other outcomes

Internet skills, sources of support and benefiting from internet use

This study added communication Internet skills to an existing skill framework of operational, formal, information, and strategic skills. The study investigated how people deal with inadequate skill levels by identifying support sources. Furthermore, we investigated which of the Internet skills actually matter for attaining beneficial Internet outcomes and whether support sources employed moderate these effects. Results of a large-scale survey revealed three support patterns: independents, social support seekers, and formal help seekers. The newly added communication skills prove to be an important addition because they have an independent effect on beneficial Internet use. The group of independent Internet users benefited more from Internet use than formal help seekers and much more than social support seekers. Internet communication skills hold the potential for achieving a high degree of independence in using the Internet by compensating for information skills so as to attain beneficial Internet outcomes

Oncogenic senescence: a multi-functional perspective.

Cellular senescence is defined as an irreversible growth arrest with the acquisition of a distinctive secretome. The growth arrest is a potent anticancer mechanism whereas the secretome facilitates wound healing, tissue repair, and development. The senescence response has also become increasingly recognized as an important contributor to aging and age-related diseases, including cancer. Although oncogenic mutations are capable of inducing a beneficial senescence response that prevents the growth of premalignant cells and promotes cancer immune-surveillance, the secretome of senescent cells also includes factors with pro-tumorigenic properties. On June 23rd and 24th, 2016, the Division of Cancer Biology of the National Cancer Institute sponsored a workshop to discuss the complex role of cellular senescence in tumorigenesis with the goal to define the major challenges and opportunities within this important field of cancer research. Additionally, it was noted how the development of novel tools and technologies are required to accelerate research into a mechanistic understanding of senescent cells in carcinogenesis in order to overcome the current limitations in this exciting, yet ill-defined area

On an evaluation of transformation languages in a fully XML-driven framework for video content adaptation

Bitstream Structure Descriptions (BSDs) allow taking the complexity of transforming scalable bitstreams from the compressed domain to the semantic domain. These descriptions are an essential part of an XUL-driven video adaptation framework. The performance of a BSD transformation engine is very important in such an architecture. This paper evaluates the efficiency of XML-based transformation languages in our video adaptation framework. XSLT, STX, and a hybrid solution are compared to each other in terms of execution times, memory consumption, and user-friendliness. Our experiments show that STX is the preferred solution when speed and low-memory are important. The hybrid solution is competitive in terms of memory consumption and is more user-friendly than STX. Although XSLT is relative fast, its memory consumption is very high

Developing policy aimed at 21st-century digital skills for the creative industries:an interview study with founders and managing directors

The creative industry is a sector where digitisation inevitably changes work practices and the skill requirements are high. The rapid digitisation makes it imperative for workers to acquire digital skills beyond mere technical use. The aim of this study is twofold: (1) to offer a deeper analysis of the nature and level of 21st-century digital skills and (2) to explore the roles of both individual workers and organisations in skill development. In total, 24 interviews were conducted with founders and managing directors of creative organisations based in the Netherlands. The results show that they believe that workers’ technical skill levels are naturally high; while in fact, digital skills might require attention when content-related aspects are considered. The first priority in this case should be to raise awareness within an organisation’s management. Thereafter, intentional and structural efforts on the part of individual workers and organisations are needed to improve skill development practices in the workplace.</p

Exploring the Internet Access of Indonesian SME Entrepreneurs

The Internet opens up many new business prospects for small and medium enterprises (SMEs). However, there are still many SME entrepreneurs who are reluctant to go online despite this opportunity. The main purpose of this research is to explore facts about the internet access among Indonesian SME entrepreneurs. Unfortunately, there is only a little empirical evidence concerning it. However, through focus group discussions, we were assisted to gain a better outlook on internet access motivation, internet physical access, internet access skills, and internet usage of the SME entrepreneurs in Indonesia. The results revealed that there are still many entrepreneurs who do not use the internet and even do not understand that internet support can improve the performance of their businesses. In other words, the SME entrepreneurs are still in lack of motivation and skills such as internet information skills, internet communication skills, internet content creation skills and internet marketing skills

The compoundness and sequentiality of digital inequality

Through a survey with a representative sample of Dutch Internet users, this paper examines compound digital exclusion, that is, whether a person who lacks a particular digital skill also lacks another kind of skill; whether a person who does not engage in a particular way online is also less likely to engage in other ways; and whether a person who does not achieve a certain outcome online is also less likely to achieve another type of outcome. We also tested sequential digital exclusion, whether a lower level of digital skills leads to lower levels of engagement with the Internet resulting in a lower likelihood of an individual achieving tangible outcomes. Both types of digital exclusion are a reality. A certain use can have a strong relation with an outcome in a different domain. Furthermore, those who achieve outcomes in one domain do not necessarily achieve outcomes in another domain. To get a comprehensive picture of the nature of digital exclusion, it is necessary to account for different domains in research

Overexpression of the E2 ubiquitin–conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation

An overabundance of UbcH10 disrupts mitotic checkpoint signaling as a result of a degradation of cyclin B, increasing spontaneous and carcinogen-induced tumor formation in transgenic mice