5,244 research outputs found

    Gentrification and Neighborhood Housing Cycles: Will America’s Future Downtowns Be Rich?

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    This paper identifies a new factor, the age of the housing stock, that affects where high- and low-income neighborhoods are located in U.S. cities. High-income households, driven by a high demand for housing services, will tend to locate in areas of the city where the housing stock is relatively young. Because cities develop and redevelop from the center outward over time, the location of these neighborhoods varies over the city’s history. The model predicts a suburban location for the rich in an initial period, when young dwellings are found only in the suburbs, while predicting eventual gentrification once central redevelopment creates a young downtown housing stock. Empirical work indicates that if the influence of spatial variation in dwelling ages were eliminated, longstanding central city/suburban disparities in neighborhood economic status would be reduced by up to 50 percent. Model estimates further predict that between 2000 and 2020, central-city/suburban differences in economic status will widen somewhat in smaller cities but narrow sharply in the largest American cities as they become more gentrified.

    The Radial Masa in a Free Group Factor is Maximal Injective

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    The radial (or Laplacian) masa in a free group factor is the abelian von Neumann algebra generated by the sum of the generators (of the free group) and their inverses. The main result of this paper is that the radial masa is a maximal injective von Neumann subalgebra of a free group factor. We also investigate tensor products of maximal injective algebras. Given two inclusions Bi⊂MiB_i\subset M_i of type I\mathrm{I} von Neumann algebras in finite von Neumann algebras such that each BiB_i is maximal injective in MiM_i, we show that the tensor product B1 ⊗ˉ B2B_1\ \bar{\otimes}\ B_2 is maximal injective in $M_1\ \bar{\otimes}\ M_2$ provided at least one of the inclusions satisfies the asymptotic orthogonality property we establish for the radial masa. In particular it follows that finite tensor products of generator and radial masas will be maximal injective in the corresponding tensor product of free group factors.Comment: 25 Pages, Typos corrected and exposition improve

    Gentrification and Neighborhood Housing Cycles: Will America's Future Downtowns be Rich?

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    This paper identifies a new factor, the age of the housing stock, that affects where high- and low-income neighborhoods are located in U.S. cities. High-income households, driven by a high demand for housing services, will tend to locate in areas of the city where the housing stock is relatively young. Because cities develop and redevelop from the center outward over time, the location of these neighborhoods varies over the city’s history. The model predicts a suburban location for the rich in an initial period, when young dwellings are found only in the suburbs, while predicting eventual gentrification once central redevelopment creates a young downtown housing stock. Empirical work indicates that if the influence of spatial variation in dwelling ages were eliminated, longstanding central city/suburban disparities in neighborhood economic status would be reduced by up to 50 percent. Model estimates further predict that between 2000 and 2020, central-city/suburban differences in economic status will widen somewhat in smaller cities but narrow sharply in the largest American cities as they become more gentrified.spatial expansion of cities, housing cycles, urban expansion

    Sensor data and metadata standards review for UKCEH

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    This report contains a review and summary of a number of technical specifications originating with the ISO, OGC and W3C standards bodies in the field of earth observations and sensor networks, with the aim of developing a data model appropriate for CEH sensor data. In particular it recommends the development of a JSON-LD based format built around core concepts drawn jointly from ISO19156 Observations and Measurements and W3C Semantic Sensor Networks (SSN)/Sensor, Observation, Sample and Actuator (SOSA); the use of the Complex Property Model for semantically grounded property descriptions; OGC Sensor ML for the description of sensor instances and types; and INSPIRE Environmental Monitoring Facilities for describing sites and their monitoring capabilities. For time series representation it recommends the use of observation collections (a SSN/SOSA extension) which also serve as a point of attachment for property/values shared by all observations in a collection

    Multistep self-assembly of heteroleptic magnesium and sodium-magnesium benzamidinate complexes

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    Reaction of the magnesium bis-alkyl Mg(CH2SiMe3)(2) and the sodium amide NaHMDS (where HMDS = N(SiMe3)(2)) with benzonitrile yields the homometallic heteroleptic complex [PhC(NSiMe3)(2)Mg{mu-NC(CH2SiMe3)Ph}](2) (1). It appears that at least six independent reactions must have occurred in this one-pot reaction to arrive at this mixed benzamidinate ketimido product. Two benzonitrile solvated derivatives of Mg(CH2SiMe3)(2) (5a and 5b) have been synthesized, with 5a crystallographically characterized as a centrosymmetric (MgC)(2) cyclodimer. When, the components of 5a are allowed to react for longer, partial addition of the Mg-alkyl unit across the C N triple bond occurs to yield the trimeric species (Me3SiCH2)(2)Mg-3[mu-N=C(CH2SiMe3)Ph](4)center dot 2N CPh (6), with bridging ketimido groups and terminal alkyl groups. Finally, using the same starting materials as that which produced 1, but altering their order of addition, a magnesium bis-alkyl unit is inserted into the Na-N bonds of a benzamidinate species to yield a new sodium magnesiate complex, PhC(NSiMe3)(2)Mg(mu-CH2SiMe3)(2)Na center dot 2TMEDA (7). The formation of 7 represents a novel (insertion) route to mixed-metal species of this kind and is the first Such example to contain a bidentate terminal anion attached to the divalent metal center. All new species are characterized by H-1 and C-13 NMR spectroscopy and where appropriate by IR spectroscopy. The solid-state structures of complexes 1, 5a, and 7 have also been determined and are disclosed within

    Recombinant hirudin: kinetic mechanism for the inhibition of human thrombin

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    Recombinant hirudin variant-2(Lys47 ), was found to be a competitive inhibitor of human α-thrombin with respect to peptidyl p-Miitroanilide substrates. These results contrast with those of Degryse and coworkers that suggest that recombinant hirudin variant-2(Lys47) inhibited thrombin by a non-competitive mechanism [Degryse et al. (1989) Protein Engng, 2, 459-465], γ-Thrombin, which can arise from α-thrombin by autolysis, was shown to have an affinity for recombinant hirudin variant-2(Lys47) that was four orders of magnitude lower than that of α-thrombin. It was demonstrated that the apparent noncompetitive mechanism observed previously was probably caused by a contamination of the thrombin preparation by γ-thrombin. Comparison of the inhibition of α-thrombin by recombinant hirudins variant-2(Lys47) and variant-1, which differ from one another in eight out of 65 amino acids, indicated that the two variants have essentially the same kinetic parameter

    Foreword

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    Early Middle Cambrian bituminous coquinoid limestones from a tectonically isolated outcrop in southwestern Kyrgyzstan yield a remarkably diverse fauna, with stem-group cnidarians, trilobites, rhynchonelliformean brachiopods, and other shelly fossils. The fossil site is in the northern foothills of the Turkestan Range and thus forms part of the westernmost extension of the South Tien Shan. The fauna includes two fairly well known trilobite species, Glabrella ventrosa Lermontova, 1940 and Dorypyge richthofeniformis Lermontova, 1940, that provide confident support for an Amgan age of the rocks. New described taxa include the stem-group cnidarian Cambroctoconus kyrgyzstanicus Peel sp. nov., the trilobite Olenoides sagittatus Geyer sp. nov., and the helcionelloid Manasoconus bifrons Peel gen. et sp. nov. Additional fossils within the samples include the trilobites Olenoides sp. A, Kootenia sp., and Pseudoeteraspis? sp.; the rhynchonelliform brachiopods Narynella cf. ferganensis (Andreeva, 1962), Narynella? sp., Austrohedra? sp. nov., and two species of uncertain generic affinity; the tommotiid Tesella sp.; the hyolithelminth Hyolithellus sp.; and the palaeoscolecid Hadimopanella oezgueli Gedik, 1977. Of particular interest is Cambroctoconus kyrgyzstanicus with an octagonal corallum and a sparsely septate calyx

    Functional characterization of a constitutively active kinase variant of Arabidopsis phototropin 1

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    Phototropins (phots) are plasma membrane-associated serine/threonine kinases that coordinate a range of processes linked to optimizing photosynthetic efficiency in plants. These photoreceptors contain two light-, oxygen- or voltage-sensing (LOV) domains within their N-terminus, with each binding one molecule of flavin mononucleotide (FMN) as a UV/blue light absorbing chromophore. Although phots contain two LOV domains, light-induced activation of the C-terminal kinase domain and subsequent receptor autophosphorylation is controlled primarily by the Aâ€Čα-LOV2-Jα photosensory module. Mutations that disrupt interactions between the LOV2-core and its flanking helical segments can uncouple this mode of light regulation. Yet, the impact of these mutations on phot function in Arabidopsis has not been explored. Here, we report that histidine substitution of Arg-472 located within the Aâ€Čα-helix of Arabidopsis phot1 to histidine results in constitutively activates kinas activity in vitro without affecting LOV2 photochemistry. Expression analysis of phot1 R472H in the phot-deficient mutant confirmed that it is autophosphorylated in darkness in vivo, but was unable to initiate phot1 signaling in the absence of light. Instead, we found that the phot1 R472H mutant is poorly functional under low-light conditions, but can restore phototropism, chloroplast accumulation, stomatal opening, and leaf positioning and expansion at higher light intensities. Our findings suggest that Arabidopsis can adapt to the elevated phosphorylation status of the phot1 R472H mutant by in part reducing its stability, whereas the activity the mutant under high-light conditions can be attributed to additional increases in LOV2-mediated photoreceptor autophosphorylation
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