Controlled single electron transfer between Si:P dots

We demonstrate electrical control of Si:P double dots in which the potential is defined by nanoscale phosphorus doped regions. Each dot contains approximately 600 phosphorus atoms and has a diameter close to 30 nm. On application of a differential bias across the dots, electron transfer is observed, using single electron transistors in both dc- and rf-mode as charge detectors. With the possibility to scale the dots down to few and even single atoms these results open the way to a new class of precision-doped quantum dots in silicon.Comment: 3 figures, 3 page

Charge-based silicon quantum computer architectures using controlled single-ion implantation

We report a nanofabrication, control and measurement scheme for charge-based silicon quantum computing which utilises a new technique of controlled single ion implantation. Each qubit consists of two phosphorus dopant atoms ~50 nm apart, one of which is singly ionized. The lowest two energy states of the remaining electron form the logical states. Surface electrodes control the qubit using voltage pulses and dual single electron transistors operating near the quantum limit provide fast readout with spurious signal rejection. A low energy (keV) ion beam is used to implant the phosphorus atoms in high-purity Si. Single atom control during the implantation is achieved by monitoring on-chip detector electrodes, integrated within the device structure, while positional accuracy is provided by a nanomachined resist mask. We describe a construction process for implanted single atom and atom cluster devices with all components registered to better than 20 nm, together with electrical characterisation of the readout circuitry. We also discuss universal one- and two-qubit gate operations for this architecture, providing a possible path towards quantum computing in silicon.Comment: 9 pages, 5 figure

Stability of Waves in Multi-component DNLS system

In this work, we systematically generalize the Evans function methodology to address vector systems of discrete equations. We physically motivate and mathematically use as our case example a vector form of the discrete nonlinear Schrodinger equation with both nonlinear and linear couplings between the components. The Evans function allows us to qualitatively predict the stability of the nonlinear waves under the relevant perturbations and to quantitatively examine the dependence of the corresponding point spectrum eigenvalues on the system parameters. These analytical predictions are subsequently corroborated by numerical computations.Comment: to appear Journal of Physics A: Mathematical and Theoretica

Preparation of anti-vicinal amino alcohols: asymmetric synthesis of D-erythro-Sphinganine, (+)-spisulosine and D-ribo-phytosphingosine

Two variations of the Overman rearrangement have been developed for the highly selective synthesis of anti-vicinal amino alcohol natural products. A MOM-ether directed palladium(II)-catalyzed rearrangement of an allylic trichloroacetimidate was used as the key step for the preparation of the protein kinase C inhibitor D-erythro-sphinganine and the antitumor agent (+)-spisulosine, while the Overman rearrangement of chiral allylic trichloroacetimidates generated by asymmetric reduction of an alpha,beta-unsaturated methyl ketone allowed rapid access to both D-ribo-phytosphingosine and L-arabino-phytosphingosine

CXCR2 deficient mice display macrophage-dependent exaggerated acute inflammatory responses

CXCR2 is an essential regulator of neutrophil recruitment to inflamed and damaged sites and plays prominent roles in inflammatory pathologies and cancer. It has therefore been highlighted as an important therapeutic target. However the success of the therapeutic targeting of CXCR2 is threatened by our relative lack of knowledge of its precise in vivo mode of action. Here we demonstrate that CXCR2-deficient mice display a counterintuitive transient exaggerated inflammatory response to cutaneous and peritoneal inflammatory stimuli. In both situations, this is associated with reduced expression of cytokines associated with the resolution of the inflammatory response and an increase in macrophage accumulation at inflamed sites. Analysis using neutrophil depletion strategies indicates that this is a consequence of impaired recruitment of a non-neutrophilic CXCR2 positive leukocyte population. We suggest that these cells may be myeloid derived suppressor cells. Our data therefore reveal novel and previously unanticipated roles for CXCR2 in the orchestration of the inflammatory response

1S-2S Spectrum of a Hydrogen Bose-Einstein Condensate

We calculate the two-photon 1S-2S spectrum of an atomic hydrogen Bose-Einstein condensate in the regime where the cold collision frequency shift dominates the lineshape. WKB and static phase approximations are made to find the intensities for transitions from the condensate to motional eigenstates for 2S atoms. The excited state wave functions are found using a mean field potential which includes the effects of collisions with condensate atoms. Results agree well with experimental data. This formalism can be used to find condensate spectra for a wide range of excitation schemes.Comment: 13 pages, 4 figure

Evidence for textile production in Rabati, Georgia, during the Bedeni phase of the Early Kurgan period

Georgian-Australian excavations in the multi-period settlement site of Rabati, located in southwest Georgia, have produced substantial evidence of textile manufacturing in the Early Kurgan, Bedeni period (2400–2000 BCE). The results of Palynological, Non-Pollen Palynomorph (NPP), Archaeobotanical, bone and fired clay tool analyses presented here have identified fibres of flax and hemp. The presence of cotton is the earliest evidence for this fibre in the region, pointing to trade in the commodity rather than its local cultivation. Also identified were coloured fibres and the possible sources of dye found in the Early Kurgan contexts at the site are discussed. The large number of textile manufacturing implements concentrated in one area of Rabati may indicate that this production was commercial rather than a domestic activity. An active, local textile industry during this period of growing social complexity has significant implications for the development of the emerging elite elements in an increasingly stratified society

Cultural Predictors of Facial Ethnicity Preference in the Miskitu and Mestizos of Rural Nicaragua

Both basic visual experience and cultural associations with race and ethnicity may contribute to the extent observers do or do not favor some facial ethnicity cues over others. Given that visual media contain a highly biased selection of faces, with Whiteness both over-represented and strongly privileged in film and television, communities for whom visual media are relatively novel may experience an additional, pervasive source of attitudes to facial ethnicity markers. In the current research, we compared individuals of Mestizo and Miskitu identities living in communities on the Caribbean Coast of Nicaragua with, and without, regular access to television on their relative preference for facial stimuli manipulated to look more or less White (Black vs White, Black vs Mestizo, Mestizo vs White). Results showed that all communities showed an overall preference for images with lighter skin, although changes in facial shape did not affect preferences. Those who had attended more years of education preferred whiter faces than those with less education, and those who watched more television preferred whiter faces more only where color (rather than shape) had been manipulated. Results are discussed in terms of the broader relations around ethnicity, status, and technological transition in this area