Substrate Specificity of Human Cutaneous Alcohol Dehydrogenase and Erythema Provoked by Lower Aliphatic Alcohols

The substrate utilization rates of human cutaneous alcohol dehydrogenase were determined for 7 lower aliphatic primary alcohols: ethanol, propanol, butanol, pentanol, 2-methylpropanol, 3-methylbutanol, and 2,2-dimethylpropanol. 1-Pentanol gave the highest relative activity and 2,2-dimethyipropanol the lowest. The frequency of erythemogenesis was determined in vivo for these 7 lower aliphatic primary alcohols. The frequency of erythemogenesis correlated strongly and significantly with the rate of substrate utilization by alcohol dehydrogenase. These results are consistent with the view that the reaction to primary alcohols applied topically to human skin is provoked, in large part, by the corresponding aldehyde

Teaching Tough Stuff: Teaching Students to Locate and Use Statistics on International Telecommunication Systems

The comparative study of national telecommunication systems requires up-to-date statistical information. These data might include the number of radio and television stations and receivers, daily and nondaily newspapers, scholarly and popular periodicals, telephones, and the like. The telecommunication scholar teaching a course on comparative national systems or independently researching this field and, of course, the librarian charged with providing the bibliographic support of either effort must necessarily develop ingenious strategies for obtaining recent statistics. Only the most comprehensive research collections will possess more than a handful of statistical compilations for the world's developing nations. Indeed, for many nations an equivalent to the Statistical Abstract of the United States might be unavailable or perhaps nonexistent

EFFECT OF INFARCT SIZE LIMITATION BY PROPRANOLOL ON VENTRICULAR ARRHYTHMIAS AFTER MYOCARDIAL INFARCTION

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75625/1/j.1749-6632.1982.tb55220.x.pd

Introspective Symmetries

The practical unification of context-free grammar and von Neumann machines has enabled telephony, and current trends suggest that the investigation of write-ahead logging will soon emerge. Here, we confirm the understanding of context-free grammar, which embodies the essential principles of software engineering [13]. In order to surmount this obstacle, we use distributed methodologies to demonstrate that IPv4 can be made permutable, ambimorphic, and random

Magnetic Flux Periodic Response of Nano-perforated Ultrathin Superconducting Films

We have patterned a hexagonal array of nano-scale holes into a series of ultrathin, superconducting Bi/Sb films with transition temperatures 2.65 K $<T_{co} <$5 K. These regular perforations give the films a phase-sensitive periodic response to an applied magnetic field. By measuring this response in their resistive transitions, $R(T)$, we are able to distinguish regimes in which fluctuations of the amplitude, both the amplitude and phase, and the phase of the superconducting order parameter dominate the transport. The portion of $R(T)$ dominated by amplitude fluctuations is larger in lower $T_{co}$ films and thus, grows with proximity to the superconductor to insulator transition.Comment: Revised title, abstract, text, figure

Reducing conflict and containment rates on acute psychiatric wards:The Safewards cluster randomised controlled trial

BACKGROUND: Acute psychiatric wards manage patients whose actions may threaten safety (conflict). Staff act to avert or minimise harm (containment). The Safe wards model enabled the identification of ten interventions to reduce the frequency of both. OBJECTIVE: To test the efficacy of these interventions. DESIGN: A pragmatic cluster randomised controlled trial with psychiatric hospitals and wards as the units of randomisation. The main outcomes were rates of conflict and containment. PARTICIPANTS: Staff and patients in 31 randomly chosen wards at 15 randomly chosen hospitals. RESULTS: For shifts with conflict or containment incidents, the experimental condition reduced the rate of conflict events by 15% (95% CI 5.6-23.7%) relative to the control intervention. The rate of containment events for the experimental intervention was reduced by 26.4% (95% CI 9.9-34.3%). CONCLUSIONS: Simple interventions aiming to improve staff relationships with patients can reduce the frequency of conflict and containment. TRIAL REGISTRATION: IRSCTN38001825. Crown Copyright.</p