Fathers\u27 Trait Verbal Aggressiveness and Argumentativeness as Predictors of Adult Sons\u27 Perceptions of Fathers\u27 Sarcasm, Criticism, and Verbal Aggressiveness

This research used Infante\u27s (1987) conceptualization of trait verbal aggressiveness and argumentativeness to analyze adult males’ perceptions of their fathers’ messages. In the present study, fathers’ self‐reports of verbal aggressiveness and argumentativeness were used to predict their adult sons’ reports of fathers’ sarcasm, criticism, and global verbal aggressiveness. Results of multivariate regression analyses indicated that (1) fathers’ argumentativeness accounted for a significant percentage of variance in the dependent variable set but did not contribute significantly to the univariate equations and (2) fathers’ verbal aggressiveness explained a significant percentage of the multivariance and contributed significantly to each univariate equation. Overall, the predictor set explained 39.32% of the variance in the dependent variable set. As predicted, the preponderance of the effect (30.05%) was due to fathers’ verbal aggressiveness. Implications are discussed

Fathers\u27 Trait Verbal Aggressiveness and Argumentativeness as Predictors of Adult Sons\u27 Perceptions of Fathers\u27 Sarcasm, Criticism, and Verbal Aggressiveness

This research used Infante\u27s (1987) conceptualization of trait verbal aggressiveness and argumentativeness to analyze adult males’ perceptions of their fathers’ messages. In the present study, fathers’ self‐reports of verbal aggressiveness and argumentativeness were used to predict their adult sons’ reports of fathers’ sarcasm, criticism, and global verbal aggressiveness. Results of multivariate regression analyses indicated that (1) fathers’ argumentativeness accounted for a significant percentage of variance in the dependent variable set but did not contribute significantly to the univariate equations and (2) fathers’ verbal aggressiveness explained a significant percentage of the multivariance and contributed significantly to each univariate equation. Overall, the predictor set explained 39.32% of the variance in the dependent variable set. As predicted, the preponderance of the effect (30.05%) was due to fathers’ verbal aggressiveness. Implications are discussed

Development of a low-power, low-cost front end electronics module for large scale distributed neutrino detectors

A number of concepts have been presented for distributed neutrino detectors formed of large numbers of autonomous detectors. Examples include the Antarctic Ross Ice Shelf Antenna Neutrino Array (ARIANNA) [Barwick 2006], as well as proposed radio extensions to the IceCube detector at South Pole Station such as AURA and IceRay. [Besson 2008]. We have focused on key enabling technical developments required by this class of experiments. The radio Cherenkov signal, generated by the Askaryan mechanism [Askaryan 1962, 1965], is impulsive and coherent up to above 1 GHz. In the frequency domain, the impulsive character of the emission results in simultaneous increase of the power detected in multiple frequency bands. This multiband triggering approach has proven fruitful, especially as anthropogenic interference often results from narrowband communications signals. A typical distributed experiment of this type consists of a station responsible for the readout of a cluster of antennas either near the surface of the ice or deployed in boreholes. Each antenna is instrumented with a broadband low-noise amplifier, followed by an array of filters to facilitate multi-band coincidence trigger schemes at the antenna level. The power in each band is detected at the output of each band filter, using either square-law diode detectors or log-power detectors developed for the cellular telephone market. The use of multiple antennas per station allows a local coincidence among antennas to be used as the next stage of the trigger. Station triggers can then be combined into an array trigger by comparing timestamps of triggers among stations and identifying space-time clusters of station triggers. Data from each station is buffered and can be requested from the individual stations when a multi-station coincidence occurs. This approach has been successfully used in distributed experiments such as the Pierre Auger Observatory. [Abraham et al. 2004] We identified the filters as being especially critical. The frequency range of interest, {approx}200 MHz to {approx}1.2 GHz, is a transitional region where the lumped circuit element approach taken at low frequencies begins to reach limitations due to component tolerances, component losses, and parasitic effects. Active circuits can help to mitigate against these effects at the cost of added power consumption that becomes prohibitive for distributed experiments across the band of interest. At higher frequency microstrip, stripline, and other microwave techniques come to the fore. We have developed designs and design tools for passive filters extending the high frequency techniques to the frequency range of interest. Microstrip and stripline techniques are not usually attractive here because of the large physical dimensions of the resulting circuits, but in this application the tradeoff of size against power consumption favors this choice. These techniques are also intrinsically low-cost, as the filter is built into the circuit boards and the cost of components and their assembly onto the board is avoided. The basic element of the filter tree is an impedance matched wideband diplexer. This consists of a pair of low pass and high pass filters with a shared cutoff frequency and complementary frequency responses. These are designing the lowpass filter as a high order LC filter, which can be implemented as a series of transmission line segments of varying width. This can be transformed in to a CL high pass filter with a complementary frequency response. When the two filters are coupled to a common input, the input impedances of the networks add in parallel to give a constant input impedance as a function of frequency, with power flowing into one leg or the other of the filter pair. These filters can be cascaded to divide the band into the frequency ranges of interest; the broadband impedance matching at the inputs makes coupling of successive stages straightforward. These circuits can be produced in quantity at low cost using standard PCB fabrication techniques. We have determined that to achieve best performance the circuits should be built on a low loss-tangent RF substrate. We are working in cooperation with our colleagues in condensed matter who also have a need for this capability to purchase the equipment for in-house fabrication of prototype quantities of these circuits. We plan to continue the work on these filtersusing internal funds, and produce and characterize the performance of prototypes. We also participated in deployment of a prototype detector station near McMurdo Station, Antarctica in collaboration with colleagues at UCLA and UC-Irvine. The prototype station includes a single-board computer, GPS receiver, ADC board, and Iridium satellite modem powered by an omnidirectional solar array. We operated this station in the austral summer of 2006-2007, and used the Iridium SMS mode to transmit the status of the station until the end of the daylight season

Culture of equine fibroblast-like synoviocytes on synthetic tissue scaffolds towards meniscal tissue engineering: a preliminary cell-seeding study

Introduction. Tissue engineering is a new methodology for addressing meniscal injury or loss. Synovium may be an ideal source of cells for in vitro meniscal fibrocartilage formation, however, favorable in vitro culture conditions for synovium must be established in order to achieve this goal. The objective of this study was to determine cellularity, cell distribution, and extracellular matrix (ECM) formation of equine fibroblast-like synoviocytes (FLS) cultured on synthetic scaffolds, for potential application in synovium-based meniscal tissue engineering. Scaffolds included open-cell poly-L-lactic acid (OPLA) sponges and polyglycolic acid (PGA) scaffolds cultured in static and dynamic culture conditions, and PGA scaffolds coated in poly-L-lactic (PLLA) in dynamic culture conditions.Materials and Methods. Equine FLS were seeded on OPLA and PGA scaffolds, and cultured in a static environment or in a rotating bioreactor for 12 days. Equine FLS were also seeded on PGA scaffolds coated in 2% or 4% PLLA and cultured in a rotating bioreactor for 14 and 21 days. Three scaffolds from each group were fixed, sectioned and stained with Masson’s Trichrome, Safranin-O, and Hematoxylin and Eosin, and cell numbers and distribution were analyzed using computer image analysis. Three PGA and OPLA scaffolds from each culture condition were also analyzed for extracellular matrix (ECM) production via dimethylmethylene blue (sulfated glycosaminoglycan) assay and hydroxyproline (collagen) assay. PLLA coated PGA scaffolds were analyzed using double stranded DNA quantification as areflection of cellularity and confocal laser microscopy in a fluorescent cell viability assay.Results. The highest cellularity occurred in PGA constructs cultured in a rotating bioreactor, which also had a mean sulfated glycosaminoglycan content of 22.3 µg per scaffold. PGA constructs cultured in static conditions had the lowest cellularity. Cells had difficulty adhering to OPLA and the PLLA coating of PGA scaffolds; cellularity was inversely proportional to the concentration of PLLA used. PLLA coating did not prevent dissolution of the PGA scaffolds. All cell scaffold types and culture conditions produced non-uniform cellular distribution.Discussion/Conclusion. FLS-seeding of PGA scaffolds cultured in a rotating bioreactor resulted in the most optimal cell and matrix characteristics seen in this study. Cells grew only in the pores of the OPLA sponge, and could not adhere to the PLLA coating of PGA scaffold, due to the hydrophobic property of PLA. While PGA culture in a bioreactor produced measureable GAG, no culture technique produced visible collagen. For this reason, and due to the dissolution of PGA scaffolds, the culture conditions and scaffolds described here are not recommended for inducing fibrochondrogenesis in equine FLS for meniscal tissue engineering

Feline Immunodeficiency Virus Integration in B-Cell Lymphoma Identifies a Candidate Tumor Suppressor Gene on Human Chromosome 15q151

Infection with immunosuppressive lentiviruses is associated with increased cancer risk,but most studies have implicated indirect mechanisms as the tumor cells generally lack integrated viral sequences.An exception wasfound in a B-cell lymphoma (Q254) where the tumor cells contained a single integrated feline immunodeficiency virus genome. Additional analysis now indicates that feline immunodeficiency virus integration in lymphoma Q254 resulted in promoter insertion and truncation of a conserved gene on feline chromosome B3, whereas the unaffected allele of the gene appeared to be transcriptionally down-regulated. The orthologous human gene (FLJ12973), is expressed ubiquitously and encodes a WD-repeat protein with structural similarity to DDB2, the small subunit of the xeroderma pigmentosum XP-E complex. Moreover, the gene is located within a region of frequent tumor-specific deletions on chromosome 15q15. These observations demonstrate the direct mutagenic potential of the lentiviruses and identify a new candidate tumor suppressor gene

Cosmic-Ray Positrons: Are There Primary Sources?

Cosmic rays at the Earth include a secondary component originating in collisions of primary particles with the diffuse interstellar gas. The secondary cosmic rays are relatively rare but carry important information on the Galactic propagation of the primary particles. The secondary component includes a small fraction of antimatter particles, positrons and antiprotons. In addition, positrons and antiprotons may also come from unusual sources and possibly provide insight into new physics. For instance, the annihilation of heavy supersymmetric dark matter particles within the Galactic halo could lead to positrons or antiprotons with distinctive energy signatures. With the High-Energy Antimatter Telescope (HEAT) balloon-borne instrument, we have measured the abundances of positrons and electrons at energies between 1 and 50 GeV. The data suggest that indeed a small additional antimatter component may be present that cannot be explained by a purely secondary production mechanism. Here we describe the signature of the effect and discuss its possible origin.Comment: 15 pages, Latex, epsfig and aasms4 macros required, to appear in Astroparticle Physics (1999