916 research outputs found

    A contemporary analysis of the growth, effects, and adjustments to automation

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    The objective of this thesis is to compile and analyze information on automation, beginning with its background and origin and continuing through various contemporary issues, directly or indirectly related to its development; namely, the need for automation in advancing our present-day society, socially and economically; the present-day uses and future expectations; factors standing in the way or automatic development; effects, both good and bad, attributed to automation by management, labor, and business; beliefs of management, labor and business as to the methods of adjusting these effects for the benefit of all mankind; and the question concerning automation\u27s being the primary cause of unemployment reported in many communities today

    More isn't better with acute low back pain treatment

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    More isn't better with acute low back pain treatment Adding cyclobenzaprine or oxycodone/acetaminophen to naproxen for the treatment of acute low back pain does nothing more than increase adverse effects. Practice changer: Consider treating patients with acute low back pain with naproxen only, as adding cyclobenzaprine or oxycodone/acetaminophen to scheduled naproxen does not improve functional assessment at 7 days or 3 months and increases adverse effects

    Impact of environmental factors on growth and satratoxin G production by strains of Stachybotrys chartarum

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    The black mould Stachybotrys chartarum and its mycotoxins have been linked to damp building-associated illnesses. The objective of this study was to determine the effects of water availability (water activity, aw) and temperature on growth and production of satratoxin G (SG) by a macrocyclic trichothecene-producing strain (IBT 7711) and non-producing strain (IBT 1495) of S. chartarum. Growth studies were carried out on potato dextrose agar modified with glycerol to 0.995-0.92 aw at 10-37 °C. Growth extension was measured and the cultures were extracted after 10 days and a competitive enzyme-linked immunosorbent assay (ELISA) method used to quantify the SG content. Growth was optimal at 25 to 30 °C at 0.995 aw, but this was modified to 0.98 aw at 30 °C for both strains (1.4- 1.6 mm/day, respectively). The ELISA method revealed that, in contrast to growth, SG production was maximal at 20 °C with highest production at 0.98 aw (approximately 250 Όg/g mycelia). When water was freely available (0.995 aw), SG was maximally produced at 15 °C and decreased as temperature was increased. Interestingly, the strain classified as a non-toxigenic produced very low amounts of SG (<1.6 Όg/g mycelia) that were maximal at 25 °C and 0.98 aw. Contour maps for growth and SG production were developed from these data sets. These data have shown, for the first time, that growth and SG production profiles are very different in relation to key environmental conditions in the indoor environment. This will be very useful in practically determining the risk from exposure to S. chartarum and its toxins in the built env

    NĂ©gyesek kialakulĂĄsa

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    Unfixing the Studio

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    The studio remains a central idea in art and design education as a persistent physical and conceptual entity also notable for a lack of objective definition. The studio is complex, changeable, and tacit, meaning traditional modes of definition or inquiry are not always suited to furthering our understanding and recent work is starting to demonstrate the benefits of blending disciplinary-oriented and academic methods to achieve this. The paper aims to build on this and observes that there are inherently visual components to many research methodologies, all of which start with an academic justification before proceeding to some visual and spatial activity. Underlying such processes is a thought process of ‘fixing and unfixing’ that can be uniquely supported by disciplinary methods. The question explored is whether starting with visual and spatial methods can lead to, or inform, academic perspectives in design education and to what extent might one inform the other. In response, the authors engaged in a series of academic, pedagogic and practice activities and dialogues that explored this question and a condensed account of the process is offered. The paper ends with descriptions of three processes, each presented as a visual and thinking method that allows readers to explore ways of knowing of studio for themselves

    Comparison of stainless and mild steel welding fumes in generation of reactive oxygen species

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    <p>Abstract</p> <p>Background</p> <p>Welding fumes consist of a wide range of complex metal oxide particles which can be deposited in all regions of the respiratory tract. The welding aerosol is not homogeneous and is generated mostly from the electrode/wire. Over 390,000 welders were reported in the U.S. in 2008 while over 1 million full-time welders were working worldwide. Many health effects are presently under investigation from exposure to welding fumes. Welding fume pulmonary effects have been associated with bronchitis, metal fume fever, cancer and functional changes in the lung. Our investigation focused on the generation of free radicals and reactive oxygen species from stainless and mild steel welding fumes generated by a gas metal arc robotic welder. An inhalation exposure chamber located at NIOSH was used to collect the welding fume particles.</p> <p>Results</p> <p>Our results show that hydroxyl radicals (<sup>.</sup>OH) were generated from reactions with H<sub>2</sub>O<sub>2 </sub>and after exposure to cells. Catalase reduced the generation of <b><sup>.</sup></b>OH from exposed cells indicating the involvement of H<sub>2</sub>O<sub>2</sub>. The welding fume suspension also showed the ability to cause lipid peroxidation, effect O<sub>2 </sub>consumption, induce H<sub>2</sub>O<sub>2 </sub>generation in cells, and cause DNA damage.</p> <p>Conclusion</p> <p>Increase in oxidative damage observed in the cellular exposures correlated well with <b><sup>.</sup></b>OH generation in size and type of welding fumes, indicating the influence of metal type and transition state on radical production as well as associated damage. Our results demonstrate that both types of welding fumes are able to generate ROS and ROS-related damage over a range of particle sizes; however, the stainless steel fumes consistently showed a significantly higher reactivity and radical generation capacity. The chemical composition of the steel had a significant impact on the ROS generation capacity with the stainless steel containing Cr and Ni causing more damage than the mild steel. Our results suggest that welding fumes may cause acute lung injury. Since type of fume generated, particle size, and elapsed time after generation of the welding exposure are significant factors in radical generation and particle deposition these factors should be considered when developing protective strategies.</p

    Cuban Connection: Regional Role for Florida's Manatees

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    The status of the West Indian manatee [Trichechus manatus (Linnaeus, 1758)] remains enigmatic. The International Union for Conservation of Nature classifies the species as “Vulnerable” and the two subspecies [T. m. manatus (Linnaeus, 1758) and T. m. latirostris (Harlan, 1824)] as “Endangered.” The U.S. Fish and Wildlife Service now classifies West Indian manatees as “Threatened” primarily due to increased numbers of T. m. latirostris. Fully resolving the status of the species will require a better understanding of its population biology throughout the broader Caribbean region, especially the form and strength of genetic and demographic connections. Genetic studies indicate limited interbreeding among recent generations of groups of manatees separated by unsuitable coastal habitat or large expanses of open water, such as the Florida Straits. However, documentation of two, independent immigrations from Florida to Cuba within one generation raises the possibility of important demographic connections, especially if the number of manatees in Cuba is small. In addition, these events may foreshadow a change in the role that Florida's manatees play in effective conservation of T. manatus throughout its Caribbean range, with the potential for further connections as numbers of manatees in Florida increase and the availability of suitable habitat and food decreases
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