Hypoglycemia is Associated with Increased Risk for Brain Injury and Adverse Neurodevelopmental Outcome in Neonates at Risk for Encephalopathy

OBJECTIVE: To investigate the contribution of hypoglycemia in the first 24 hours after birth to brain injury in term newborns at risk for neonatal encephalopathy. STUDY DESIGN: A prospective cohort of 94 term neonates born between 1994 and 2010 with early postnatal brain MRI studies were analyzed for regions of brain injury. Neurodevelopmental outcome was assessed at one year of age. RESULTS: Hypoglycemia (glucose <46mg/dL) in the first 24 hours after birth was detected in 16% of the cohort. Adjusting for potential confounders of early perinatal distress and need for resuscitation, neonatal hypoglycemia was associated with a 3.72-fold increased odds of corticospinal tract injury (P=0.047). Hypoglycemia was also associated with 4.82-fold increased odds of one-point worsened neuromotor score (P=0.038) and a 15-point lower cognitive and language score on the Bayley Scales of Infant Development (P=0.015). CONCLUSION: Neonatal hypoglycemia is associated with additional risks in the setting of neonatal encephalopathy with increased corticospinal tract injury and adverse motor and cognitive outcomes

Media and the Imaginary in History

This is an Accepted Manuscript of an article published by Taylor & Francis in Media History on 19th March 2014, available online: http://wwww.tandfonline.com/10.1080/13688804.2014.898904This paper discusses how media theory and history should approach specimens of evidence about the cultural reception of media pertaining to the realms of the fantastic, such as speculations, predictions, dreams, and other forms of fantasy regarding media. It argues that the role of the imaginary in the history of media can be fully comprehended only by employing a perspective which is dynamic in time. In different phases of a medium's evolution, in fact, we find different fantasies; it follows that we need specific approaches to study them. The article discusses fantasies which are specific to three stages in media change: those preceding the actual invention of a medium; those accompanying the earliest period after the introduction of a new medium; and those connected to old media. © 2014 Taylor and Francis