4,731 research outputs found

    Between Philosophy and Art

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    Similarity and difference, patterns of variation, consistency and coherence: these are the reference points of the philosopher. Understanding experience, exploring ideas through particular instantiations, novel and innovative thinking: these are the reference points of the artist. However, at certain points in the proceedings of our Symposium titled, Next to Nothing: Art as Performance, this characterisation of philosopher and artist respectively might have been construed the other way around. The commentator/philosophers referenced their philosophical interests through the particular examples/instantiations created by the artist and in virtue of which they were then able to engage with novel and innovative thinking. From the artists’ presentations, on the other hand, emerged a series of contrasts within which philosophical and artistic ideas resonated. This interface of philosopher-artist bore witness to the fact that just as art approaches philosophy in providing its own analysis, philosophy approaches art in being a co-creator of art’s meaning. In what follows, we discuss the conception of philosophy-art that emerged from the Symposium, and the methodological minimalism which we employed in order to achieve it. We conclude by drawing out an implication of the Symposium’s achievement which is that a counterpoint to Institutional theories of art may well be the point from which future directions will take hold, if philosophy-art gains traction

    Yield Reserve Program Costs in the Virginia Coastal Plain

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    A proposed Yield Reserve Program designed to compensate farmers for any reduced yields resulting from nitrogen (N) application rates reduced to below recommended rates is evaluated. Assuming that farmers currently follow Extension recommendations for applying N, Yield Reserve Program participation reduces expected net revenue by 10to10 to 13/ha. The Yield Reserve Program reduces expected net revenue by 17to17 to 20/ha for farmers who apply N to maximize expected net revenue. Farmers’ costs of participation increase with lower probabilities of inadequate rainfall and higher corn prices and decline with higher N prices. The Yield Reserve Program can significantly reduce N applications to cropland, which may reduce N content of surface waters, but the costs to taxpayers and farmers will depend on how the program is implemented.compliance cost, nitrogen fertilizer, nonpoint source pollution, policy, yield response function, Agricultural and Food Policy, Crop Production/Industries,

    Wind-tunnel investigation of aerodynamic characteristics and wing pressure distributions of an airplane with variable-sweep wings modified for laminar flow

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    A wind tunnel test was conducted to evaluate the aerodynamic characteristics and wing pressure distributions of a variable wing sweep aircraft having wing panels that are modified to promote laminar flow. The modified wing section shapes were incorporated over most of the exposed outer wing panel span and were obtained by extending the leading edge and adding thickness to the existing wing upper surface forward of 60 percent chord. Two different wing configurations, one each for Mach numbers 0.7 and 0.8, were tested on the model simultaneously, with one wing configuration on the left side and the other on the right. The tests were conducted at Mach numbers 0.20 to 0.90 for wing sweep angles of 20, 25, 30, and 35 degrees. Longitudinal, lateral and directional aerodynamic characteristics of the modified and baseline configurations, and selected pressure distributions for the modified configurations, are presented in graphical form without analysis. A tabulation of the pressure data for the modified configuration is available as microfiche

    Planetary geosciences, 1989-1990

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    NASA's Planetary Geosciences Programs (the Planetary Geology and Geophysics and the Planetary Material and Geochemistry Programs) provide support and an organizational framework for scientific research on solid bodies of the solar system. These research and analysis programs support scientific research aimed at increasing our understanding of the physical, chemical, and dynamic nature of the solid bodies of the solar system: the Moon, the terrestrial planets, the satellites of the outer planets, the rings, the asteroids, and the comets. This research is conducted using a variety of methods: laboratory experiments, theoretical approaches, data analysis, and Earth analog techniques. Through research supported by these programs, we are expanding our understanding of the origin and evolution of the solar system. This document is intended to provide an overview of the more significant scientific findings and discoveries made this year by scientists supported by the Planetary Geosciences Program. To a large degree, these results and discoveries are the measure of success of the programs

    The Astronomy of Africa’s Health Systems Literature During the MDG Era: Where Are the Systems Clusters?

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    The volume of literature on health systems in sub-Saharan Africa has been expanding since the 2000 MDG era. Focus has remained generally on categorical health themes rather than systems concepts. Topics such as scaling-up, organizational development, data use for decision making, logistics, and financial planning remain underrepresented. And quite surprisingly, implementation science remains something of a “black hole.” But bibliometric evidence suggests there is a shift in focus that may soon address these gaps

    A 3D <i>in vitro</i> model reveals differences in the astrocyte response elicited by potential stem cell therapies for CNS injury.

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    Aim: This study aimed to develop a 3D culture model to test the extent to which transplanted stem cells modulate astrocyte reactivity, where exacerbated glial cell activation could be detrimental to CNS repair success. Materials & methods: The reactivity of rat astrocytes to bone marrow mesenchymal stem cells, neural crest stem cells (NCSCs) and differentiated adipose-derived stem cells was assessed after 5 days. Schwann cells were used as a positive control. Results: NCSCs and differentiated Schwann cell-like adipose-derived stem cells did not increase astrocyte reactivity. Highly reactive responses to bone marrow mesenchymal stem cells and Schwann cells were equivalent. Conclusion: This approach can screen therapeutic cells prior to in vivo testing, allowing cells likely to trigger a substantial astrocyte response to be identified at an early stage. NCSCs and differentiated Schwann cell-like adipose-derived stem cells may be useful in treating CNS damage without increasing astrogliosis

    Mathematical modelling with Bayesian inference to quantitatively characterize therapeutic cell behaviour in nerve tissue engineering

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    Cellular engineered neural tissues have significant potential to improve peripheral nerve repair strategies. Traditional approaches depend on quantifying tissue behaviours using experiments in isolation, presenting a challenge for an overarching framework for tissue design. By comparison, mathematical cell–solute models benchmarked against experimental data enable computational experiments to be performed to test the role of biological/biophysical mechanisms, as well as to explore the impact of different design scenarios and thus accelerate the development of new treatment strategies. Such models generally consist of a set of continuous, coupled, partial differential equations relying on a number of parameters and functional forms. They necessitate dedicated in vitro experiments to be informed, which are seldom available and often involve small datasets with limited spatio-temporal resolution, generating uncertainties. We address this issue and propose a pipeline based on Bayesian inference enabling the derivation of experimentally informed cell–solute models describing therapeutic cell behaviour in nerve tissue engineering. We apply our pipeline to three relevant cell types and obtain models that can readily be used to simulate nerve repair scenarios and quantitatively compare therapeutic cells. Beyond parameter estimation, the proposed pipeline enables model selection as well as experiment utility quantification, aimed at improving both model formulation and experimental design

    Flight Investigation of the Effectiveness of an Automatic Aileron Trim Control Device for Personal Airplanes

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    A flight investigation to determine the effectiveness of an automatic aileron trim control device installed in a personal airplane to augment the apparent spiral stability has been conducted. The device utilizes a rate-gyro sensing element in order to switch an on-off type of control that operates the ailerons at a fixed rate through control centering springs. An analytical study using phase-plane and analog-computer methods has been carried out to determine a desirable method of operation for the automatic trim control

    Design optimization of high-speed proprotor aircraft

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    NASA's high-speed rotorcraft (HSRC) studies have the objective of investigating technology for vehicles that have both low downwash velocities and forward flight speed capability of up to 450 knots. This paper investigates a tilt rotor, a tilt wing, and a folding tilt rotor designed for a civil transport mission. Baseline aircraft models using current technology are developed for each configuration using a vertical/short takeoff and landing (V/STOL) aircraft design synthesis computer program to generate converged vehicle designs. Sensitivity studies and numerical optimization are used to illustrate each configuration's key design tradeoffs and constraints. Minimization of the gross takeoff weight is used as the optimization objective function. Several advanced technologies are chosen, and their relative impact on future configurational development is discussed. Finally, the impact of maximum cruise speed on vehicle figures of merit (gross weight, productivity, and direct operating cost) is analyzed. The three most important conclusions from the study are payload ratios for these aircraft will be commensurate with current fixed-wing commuter aircraft; future tilt rotors and tilt wings will be significantly lighter, more productive, and cheaper than competing folding tilt rotors; and the most promising technologies are an advanced-technology proprotor for both tilt rotor and tilt wing and advanced structural materials for the folding tilt rotor
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