Guidelines in the era of realistic medicine

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Forecasting Aggregate Period Specific Birth Rates: The Time Series Properties of a Microdynamic Neoclassical Model of Fertility

This article demonstrates the value of microdata for understanding the effect of wages on life cycle fertility dynamics. Conventional estimates of neoclassical economic fertility models obtained from linear aggregate time series regressions are widely criticized for being nonrobust when adjusted for serial correlation. Moreover, the forecasting power of these aggregative neoclassical models has been shown to be inferior when compared with conventional time series models that assign no role to wages. This article demonstrates, that when neoclassical models of fertility are estimated on microdata using methods that incorporate key demographic restrictions and when they are properly aggregated, they have considerable forecasting power.

Twist transition of nematic hyperbolic hedgehogs

Stability of an idealized hyperbolic hedgehog in a nematic liquid crystal against a twist transition is investigated by extending the methodology of Rüdinger and Stark [Liq. Cryst. 26, 753 (1999)], where the hedgehog is confined between two concentric spheres. In the ideal hyperbolic-hedgehog the molecular orientation is assumed to rotate proportionally with respect to the inclination angle, θ (and in the opposite sense). However, when splay, k11, and bend, k33, moduli differ this proportionality is lost and the liquid crystal deforms relative to the ideal with bend and splay. Although slight, these deformations are shown to significantly shift the transition if k11/k33 is small. By increasing the degree of confinement the twist transition can be inhibited, a characteristic both hyperbolic and radial hedgehogs have in common. The twist transition of a hyperbolic defect that accompanies a particle is found to be well predicted by the earlier stability analysis of a thick shell

Comparisons between the squash bug egg parasitoids Ooencyrtus anasae and O. sp. (Hymenoptera: Encyrtidae): development, survival,and sex ratio in relation to temperature

Citation: Tracy, J. L., and J. R. Nechols. 1987. “Comparisons Between the Squash Bug Egg Parasitoids Ooencyrtus Anasae and O. Sp. (Hymenoptera: Encyrtidae): Development, Survival, and Sex Ratio in Relation to Temperature.” Environmental Entomology 16 (6): 1324–29. https://doi.org/10.1093/ee/16.6.1324.Laboratory investigations of the gregarious squash bug egg parasitoids Ooencyrtus anasae and O. n. sp. near anasae (O. sp.) were conducted at 20.8, 23.0, and 26.6°C. In both species, total developmental periods (egg to eclosed adult) were inversely related to temperature. Temperature had no significant influence on survivorship, progeny production, or sex ratio. At each temperature, O. anasae developed and emerged about a day earlier and produced a significantly higher percentage of female progeny (77%) than did O. sp. (60%). Both parasitoids deposited an average of three (2-7) progeny per host. However, O. anasae consistently deposited more female eggs per host than did O. sp. Proportion of females produced per host by O. anasae tended to increase directly with number of hosts parasitized, but no such relationship was observed in O. sp. Total preimaginal survivorship in both parasitoids was about 89%. In O. sp., male progeny that developed without females emerged about a day later at all temperatures and had a lower pharate adult survivorship than did males that developed in hosts with female siblings

Resonance Raman Spectroscopic Studies of Hydroperoxo Derivatives of Cobalt-substituted Myoglobin

Recent progress in generating and stabilizing reactive heme protein enzymatic intermediates by cryoradiolytic reduction has prompted application of a range of spectroscopic approaches to effectively interrogate these species. The impressive potential of resonance Raman spectroscopy for characterizing such samples has been recently demonstrated in a number of studies of peroxo- and hydroperoxo-intermediates. While it is anticipated that this approach can be productively applied to the wide range of heme proteins whose reaction cycles naturally involve these peroxo- and hydroperoxo-intermediates, one limitation that sometimes arises is the lack of enhancement of the key intraligand ν(O–O) stretching mode in the native systems. The present work was undertaken to explore the utility of cobalt substitution to enhance both the ν(Co–O) and ν(O–O) modes of the CoOOH fragments of hydroperoxo forms of heme proteins bearing a trans–axial histidine linkage. Thus, having recently completed RR studies of hydroperoxo myoglobin, attention is now turned to its cobalt-substituted analogue. Spectra are acquired for samples prepared with 16O2 and 18O2 to reveal the ν(M–O) and ν(O–O) modes, the latter indeed being observed only for the cobalt-substituted proteins. In addition, spectra of samples prepared in deuterated solvents were also acquired, providing definitive evidence for the presence of the hydroperoxo-species

The Directional Dependence of Apertures, Limits and Sensitivity of the Lunar Cherenkov Technique to a UHE Neutrino Flux

We use computer simulations to obtain the directional-dependence of the lunar Cherenkov technique for ultra-high energy (UHE) neutrino detection. We calculate the instantaneous effective area of past lunar Cherenkov experiments as a function of neutrino arrival direction, and hence the directional-dependence of the combined limit imposed by GLUE and the experiment at Parkes. We also determine the directional dependence of the aperture of future planned experiments with ATCA, ASKAP and the SKA to a UHE neutrino flux, and calculate the potential annual exposure to astronomical objects as a function of angular distance from the lunar trajectory through celestial coordinates.Comment: 17 pages, 7 figures; Submitted to Astroparticle Physic

Entropy Evolution of the Gas in Cooling Flow Clusters

We emphasise the importance of the gas entropy in studying the evolution of cluster gas evolving under the influence of radiative cooling. On this basis, we develop an analytical model for this evolution. We then show that the assumptions needed for such a model are consistent with a numerical solution of the same equations. We postulate that the passive cooling phase ends when the central gas temperature falls to very low values. It follows a phase during which an unspecified mechanism heats the cluster gas. We show that in such a scenario the small number of clusters containing gas with temperatures below about 1 keV is simply a consequence of the radiative cooling.Comment: Contribution to Proceedings of `The Riddle of Cooling Flows in Galaxies and Clusters of Galaxies', Charlottesville, VA, USA. May 31 -- June 4, 2003. Editors: Reiprich, T. H., Kempner, J. C., and Soker, N. Requires included style fil