47 research outputs found

    IDENTIFICATION OF EMG FREQUENCY PATTERNS IN RUNNING BY WAVELET ANALYSIS AND SUPPORT VECTOR MACHINES

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    The purpose of this study was to identify EMG pattern of running at different speed and incline based on a trial-to-trial analysis. Eight subjects performed treadmill running at five different conditions (4, 5 and 6 m/s, 5m/s at 5° incline, 5m/s at 2° decline). EMG data of eight leg muscles were recorded and transformed by a wavelet analysis (van Tscharner, 2000). Ten subsequent steps of each subject and condition were classified by support vector machines. Between 93 and 100% of all EMG patterns were assigned correctly to the individual. According to the different running conditions recognition rates ranged between 78 and 88%. Hence, support vector machines can be considered as powerful nonlinear tool for the classification of dynamic EMG patterns

    Nurses' perceptions of aids and obstacles to the provision of optimal end of life care in ICU

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    Contains fulltext : 172380.pdf (publisher's version ) (Open Access

    Increasing flexibility of employees in production processes using the differential learning approach – adaptation and validation of motor learning theories

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    © Springer International Publishing AG, part of Springer Nature 2019. International expanding markets and continuous development of new customer oriented products lead to an increasing product and process variety and complexity as well as shortened product lifecycles. According to these challenges, manufacturing companies have to enhance their process flexibility to remain sustainable competitive. Due to that, employees have to deal with high flexible work processes including continuous change of constellations and objectives. These in turn require a high employee’s flexibility, adaptability and occupational competence as well as new training concepts to enable them. In the academic literature and industrial practice, exists a variety of concepts for employee’s qualification and training. However, these concepts do only partially focus the employee’s occupational competence. Therefore, an innovative learning concept based on motor learning theories was developed and empirically validated. The description of the examination design as well as the result presentation and discussion are subject of the present contribution

    Assistance system for individualization of work design [Assistenzsystem zur Individualisierung der Arbeitsgestaltung Einsatz von Smart Devices zur kontextsensitiven Arbeitsunterstützung]

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    To cope with increasing product and process diversification human labor is important for manufacturing companies. Furthermore, companies have to deal with the current demographic change including high inter-individual and intra-individual diversification of employee’s skills. In this context innovative assistance systems which individually support employees at work need to be discussed and developed

    Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily

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    Cellular signaling downstream of Ras is highly diversified and may involve many different effector molecules. A potential candidate is AF6 which was originally identified as a fusion to ALL-1 in acute myeloid leukemia. In the present work the interaction between Ras and AF6 is characterized and compared with other effectors. The binding characteristics are quite similar to Raf and RalGEF, i.e. nucleotide dissociation as well as GTPase-activating protein activity are inhibited, whereas the intrinsic GTPase activity of Ras is unperturbed by AF6 binding. Particularly, the dynamics of interaction are similar to Raf and RalGEF with a lifetime of the Ras. AF6 complex in the millisecond range. As probed by 31P NMR spectroscopy one of two major conformational states of Ras is stabilized by the interaction with AF6. Looking at the affinities of AF6 to a number of Ras mutants in the effector region, a specificity profile emerges distinct from that of other effector molecules. This finding may be useful in defining the biological function of AF6 by selectively switching off other pathways downstream of Ras using the appropriate effector mutant. Notably, among the Ras-related proteins AF6 binds most tightly to Rap1A which could imply a role of Rap1A in AF6 regulation
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