Mechanobiology of orthodontic tooth movement: An update.

The purpose of this review is to provide an update on the changes at the cellular and tissue level occurring during orthodontic force application. For the understanding of this process, knowledge of the mechanobiology of the periodontal ligament and the alveolar bone are essential. The periodontal ligament and alveolar bone make up a functional unit that undergoes robust changes during orthodontic tooth movement. Complex molecular signaling is responsible for converting mechanical stresses into biochemical events with a net result of bone apposition and/or bone resorption. Despite an improved understanding of mechanical and biochemical signaling mechanisms, it is largely unknown how mechanical stresses regulate the differentiation of stem/progenitor cells into osteoblast and osteoclast lineages. To advance orthodontics, it is crucial to gain a better understanding of osteoblast differentiation from mesenchymal stem/progenitor cells and osteoclastogenesis from the hematopoietic/monocyte lineage

Dentistry, 50 years as an academic study. Introduction |

In the Netherlands, the dentistry is an academic study. For younger colleagues, it is taken for granted, while for the older ones, it was a fiercely fought milestone achieved in 1947. Therefore, in 1997, we commemorate fifty years of dentistry as an academic study, a reason for the editorial team to ask several authors to contribute to the Dutch Journal of Dentistry on this theme. The central question is: what has the academicization of the study of dentistry yielded for the field, for the format and content of the educational program, and for the practicing dentist themselves

Het gezicht belicht:Illuminating the face

Editorial written on the occasion of the inaugural lecture by Professor Dr. A.M. Kuijpers-Jagtman at the Radboud University Nijmegen on February 11, 1993 on the occasion of the installment of an Endowed Chair by the Dutch Association of Orthodontists specifically aimed at dental and postgrduate education and research concerning cleft lip and palat

Dentistry, 50 years as an academic study. Introduction |

In the Netherlands, the dentistry is an academic study. For younger colleagues, it is taken for granted, while for the older ones, it was a fiercely fought milestone achieved in 1947. Therefore, in 1997, we commemorate fifty years of dentistry as an academic study, a reason for the editorial team to ask several authors to contribute to the Dutch Journal of Dentistry on this theme. The central question is: what has the academicization of the study of dentistry yielded for the field, for the format and content of the educational program, and for the practicing dentist themselves

Het gezicht belicht:Illuminating the face

Editorial written on the occasion of the inaugural lecture by Professor Dr. A.M. Kuijpers-Jagtman at the Radboud University Nijmegen on February 11, 1993 on the occasion of the installment of an Endowed Chair by the Dutch Association of Orthodontists specifically aimed at dental and postgrduate education and research concerning cleft lip and palat

Erratum to: Transverse dental arch relationship at 9 and 12 years in children with unilateral cleft lip and palate treated with infant orthopedics: a randomized clinical trial (DUTCHCLEFT)

The original version of the above article contained a mistakedue to incorrect alignment of entries in Tables 11 and 14during production. The entries are presented correctly below

Does treating proximal cavities in primary molars non-restoratively affect intra-arch space and alignment of successor teeth negatively?:A 4-year longitudinal study

Background: Removing plaque with toothbrush and toothpaste from proximal cavities in primary molars without restoring them follows sound cariological principles. But does this treatment affect space for and alignment of their permanent successors negatively? Hypothesis: There is no difference in impaction and displacement of the premolars, as well as in the D+E space in quadrants with three different statuses of the proximal surface of primary molars over a 4-year period. Methods: A total of 936 quadrants (466 maxillary and 470 mandibular quadrants) in 233 children were assessed. Treatment of cavities in the proximal surfaces of the primary molars consisted of amalgam and ART restorations using high-viscosity glass-ionomer cement, and cleaning of open large- and medium-sized cavities with toothbrush and toothpaste (UCT) under supervision for 220 days per year over 3 years. Dental casts were made at baseline, and after two, three, and 4 years. The D+E spaces were measured digitally. Status of the proximal surface of the primary molars was assessed by two calibrated examiners, and quadrants were grouped into normal anatomy, defective restoration, and proximal cavity. ANCOVA, ANOVA and LSD tests were applied. Results: There was a statistically significant difference between groups (p <= 0.001) and between evaluation times (p < 0.001), for the D+E space in both the maxilla and mandible. A sex difference related to the D+E space in the maxilla was found (p = 0.007). For boys, quadrants in the maxilla of the group ‘proximal cavity’ showed a significant shorter D+E space when compared to quadrants of the group ‘normal anatomy’ at the 3- and 4-year evaluation time. For girls the difference between the two groups was only present at the 3-year evaluation time. There was no significant difference between the D+E space in quadrants with defective restorations and those with normal anatomy in the mandible and in the maxilla. Displacement and impaction of the premolars showed no significant difference between groups. Conclusion: Primary molars with open proximal cavities that are cleaned with toothbrush and toothpaste do not result in displacement and impaction of the successor teeth, neither do primary molars with defective restorations in proximal tooth surfaces