An Approach for Feature extraction of Fabric using wavelet transform & defect detection using Genetic algorithm

No Abstrac

Coordinated analysis of two graphite grains from the CO3.0 LAP 031117 meteorite: First identification of a CO Nova graphite and a presolar iron sulfide subgrain

Presolar grains constitute remnants of stars that existed before the formation of the solar system. In addition to providing direct information on the materials from which the solar system formed, these grains provide ground-truth information for models of stellar evolution and nucleosynthesis. Here we report the in-situ identification of two unique presolar graphite grains from the primitive meteorite LaPaz Icefield 031117. Based on these two graphite grains, we estimate a bulk presolar graphite abundance of 5-3+7 ppm in this meteorite. One of the grains (LAP-141) is characterized by an enrichment in 12C and depletions in 33,34S, and contains a small iron sulfide subgrain, representing the first unambiguous identification of presolar iron sulfide. The other grain (LAP-149) is extremely 13C-rich and 15N-poor, with one of the lowest 12C/13C ratios observed among presolar grains. Comparison of its isotopic compositions with new stellar nucleosynthesis and dust condensation models indicates an origin in the ejecta of a low-mass CO nova. Grain LAP-149 is the first putative nova grain that quantitatively best matches nova model predictions, providing the first strong evidence for graphite condensation in nova ejecta. Our discovery confirms that CO nova graphite and presolar iron sulfide contributed to the original building blocks of the solar system.Peer ReviewedPostprint (author's final draft

Optimization of Process Parameters for CNC Turning using Taguchi Methods for EN24 Alloy Steel with Coated/Uncoated Tool Inserts

Coated and uncoated tool inserts offers certain degrees of control on the desired rate of tool wear and surface roughness to an extent. This work pursues the quest for realizing the optimal values for the significant process parameters that bears an influence on the response parameters. Experiments were conducted on the samples of EN 24 alloy steel material with the help of PVD coated TiAlN insert and uncoated carbide insert. The experimental runs carried out with proper variation in the levels. Levels are selected with the help of manufacturing catalogue and by pilot experimentation and results are recorded for further analysis. For this study, 9 runs designed using L9 orthogonal array of Taguchi Design of Experiment. Surface roughness was measured using a Mitutoyo surface tester at test lab and material removal rate is calculated by mathematical equation. The data was compiled into Minitab 17 software for analysis. The relationship between the machining parameters and the response variables were analyzed using the Taguchi Method. Optimization of process parameters is carried out by Grey Relational Analysis method (GRA). GRA method is a powerful and most versatile tool which can manipulate the input data as per requirement and comes with results that can be used to have best multi-objective in respective concerns

Changes in the lipid contents of freshwater bivalve, Lamellidens marginalis from godavari river during different seasons (M.S)

Changes in the lipid contents different soft body tissues of Lamellidens marginalis (70-77 mm in shell length) were collected from Godavari river at Paithan 49 km away from Aurangabad city. The lipid content maximum found in foot during summer and maximum showed in gonad during monsoon and winter season. The freshwater bivalve shows maximum changes in the lipid contents from gonad, as it undergoes different stages like development, maturation and spawning during different seasons

INFLUENCE OF METAL NITRATE TO FUEL RATIO ON THE MAGNETIC PROPERTIES OF NIFE2O4

Objective: Nickel ferrite nanoparticles with dimensions below 30 nm have been synthesized by sol-gel auto-combustion process. The nitrate-citrate gels were prepared from metal nitrates and citric acid solutions under various molar ratios of the metal nitrate to citric acid of 1, 2, 3 4 and 5 by sol-gel process. The results showed that nitrate citrate gels exhibit a self propagating behaviour after ignition in air at room temperature. The ratio of nitrates to citric acid also affects the combustion process. The as-prepared powder was annealed at 5000C for 6 hrs. The phase composition and structural properties of the obtained samples are investigated by X-ray diffraction (XRD) and Scanning Electron Microscopy (SEM). Analysis of the XRD patterns showed the presence of α-Fe2O3 phase and other refractions corresponding to cubic spinel structure. The lattice constant obtained from XRD data increases with metal nitrate to fuel (citric acid) ratio. PACS No: 75.50.Gg, 74.25.Ld, 43.35.C

STUDY OF FIXED DOSE COMBINATIONS IN A TERTIARY CARE HOSPITAL

ABSTRACTObjective: To study and analyze the pattern of fixed dose combinations (FDCs) in medicine outpatient clinic.Methods: The study is prospective cross-sectional study was conducted for 2 months in medicine outpatient clinic in tertiary care hospital. Aftertaking approval from Institutional Ethics Committee, the data were collected on every working day of the hospital. Prescriptions from the patientscoming to medicine outpatient clinic outpatient department were taken and required information is filled in data record form.Results: A total of 83 prescriptions were included in the study. Out of 287 drugs, 111, i.e., 39.92% were fixed dose formulations. As per drug categoryanalysis, nutritional supplements were used (47.74%). While 27.02% and 9.03% of FDCs were given for cardiovascular complains and respiratorycomplains, respectively. FDCs used for other conditions were 16.21%. About 29.72% of total FDCs are included in approved list of FDCs by DrugsController General of India (DCGI), November 2014.Conclusion: 39.92% drugs are FDCs out of total prescribed drugs. Nutritional supplements are prescribed in higher concentrations. Out of total FDCsonly 29.72% were included in DCGI approved list of FDCs and only four FDCs are found in the WHO list of essential drugs.Keywords: Fixed dose combinations, Prescriptions, Approved, Drugs Controller General of India

Evaluating thermogravimetric analysis for the measurement of drug loading in mesoporous silica nanoparticles (MSNs)

In this study, a thermogravimetric analysis (TGA) method for measuring the drug loading in mesoporous silica nanoparticles (MSNs) has been developed and evaluated in comparison with the drug loading quantification by high-performance liquid chromatography (HPLC). Indapamide was loaded into two different types of MSNs, namely Mobile Crystalline Material (MCM-41, pore size = 1.2 nm) and Santa Barbara Amorphous (SBA-15, pore size = 4.1 nm). Physical mixtures of the drug and silica gave a linear correlation between the observed and expected drug content for both TGA and HPLC, which were used for calibration purposes. The limit of detection (LOD) for the TGA method obtained from the physical mixture calibration curve was 0.77 % (w/w) and the r² value was 0.9936, whereas the HPLC had a LOD of 0.06 % (w/w) and an r² value of 0.9933. The sensitivity of the TGA method was well established using the drug loading studies, as it can detect the low loading of MCM-41 at 2.2 ± 0.21 % (w/w), compared to 5.1 ± 0.12 % (w/w) with the SBA-15. In all samples applied, the multiple comparison analysis showed an insignificant difference between the two methods (p > 0.05). The TGA data presented good evidence for using this technique as a sensitive, cost-effective, and low-variable quantitative analysis in the drug loading determination of the MSNs. TGA is not a selective method of quantification, but optimising the method using the pure and blank samples of MSNs and drug can significantly improve the sensitivity. This work provides a unique approach to apply TGA as a selective and more favourable method to characterise MSNs to do early formulation developments

ICU MONITORING SYSTEM USING RASPBERRY PI

The aim of this project is to have a quantitative assessment of the important physiological variables of patient using “Raspberry Piâ€. This system is used for measuring continuously automatically the values of patient’s physiological parameters such as body temperature, blood pressure, heart activity and humidity content present in the ICU room. This unit may be inserted in a bedside display unit to display the physiological conditions of the patients. The device detects vital parameters of the patient by the use of sensors and displays result on an monitor screen mounted on the gadget. If this values are not within the safe limit, then corresponding LED indicator will glow and alarm will start ringing

Impact of proctoring on success rates for percutaneous revascularisation of coronary chronic total occlusions.

OBJECTIVE: To assess the impact of proctoring for chronic total occlusion (CTO) percutaneous coronary intervention (PCI) in six UK centres. METHODS: We retrospectively analysed 587 CTO procedures from six UK centres and compared success rates of operators who had received proctorship with success rates of the same operators before proctorship (pre-proctored) and operators in the same institutions who had not been proctored (non-proctored). There were 232 patients in the pre-proctored/non-proctored group and 355 patients in the post-proctored group. Complexity was assessed by calculating the Japanese CTO (JCTO) score for each case. RESULTS: CTO PCI success was greater in the post-proctored compared with the pre-proctored/non-proctored group (77.5% vs 62.1%, p<0.0001). In more complex cases where JCTO≥2, the difference in success was greater (70.7% vs 49.5%, p=0.0003). After proctoring, there was an increase in CTO PCI activity in centres from 2.5% to 3.5%, p<0.0001 (as a proportion of total PCI), and the proportion of very difficult cases with JCTO score ≥3 increased from 15.3% (35/229) to 29.7% (105/354), p<0.0001. CONCLUSIONS: Proctoring resulted in an increase in procedural success for CTO PCI, an increase in complex CTO PCI and an increase in total CTO PCI activity. Proctoring may be a valuable way to improve access to CTO PCI and the likelihood of procedural success