I.S.Mu.L.T. Achilles Tendon Ruptures Guidelines

This work provides easily accessible guidelines for the diagnosis, treatment and rehabilitation of Achilles tendon ruptures. These guidelines could be considered as recommendations for good clinical practice developed through a process of systematic review of the literature and expert opinion, to improve the quality of care for the individual patient and rationalize the use of resources. This work is divided into two sessions: 1) questions about hot topics; 2) answers to the questions following Evidence Based Medicine principles. Despite the frequency of the pathology andthe high level of satisfaction achieved in treatment of Achilles tendon ruptures, a global consensus is lacking. In fact, there is not a uniform treatment and rehabilitation protocol used for Achilles tendon ruptures

Search for heavy neutral lepton production in K+ decays

A search for heavy neutral lepton production in K + decays using a data sample collected with a minimum bias trigger by the NA62 experiment at CERN in 2015 is reported. Upper limits at the 10−7 to 10−6 level are established on the elements of the extended neutrino mixing matrix |Ue4| 2 and |Uμ4| 2 for heavy neutral lepton mass in the ranges 170–448 MeV/c2 and 250–373 MeV/c2, respectively. This improves on the previous limits from HNL production searches over the whole mass range considered for |Ue4|2 and above 300 MeV/c2 for |Uμ4|2

Measurement of the very rare K+→π+ννˉK^+ \to \pi^+ \nu \bar\nu decay

The decay K+→π+νν¯ , with a very precisely predicted branching ratio of less than 10−10 , is among the best processes to reveal indirect effects of new physics. The NA62 experiment at CERN SPS is designed to study the K+→π+νν¯ decay and to measure its branching ratio using a decay-in-flight technique. NA62 took data in 2016, 2017 and 2018, reaching the sensitivity of the Standard Model for the K+→π+νν¯ decay by the analysis of the 2016 and 2017 data, and providing the most precise measurement of the branching ratio to date by the analysis of the 2018 data. This measurement is also used to set limits on BR(K+→π+X ), where X is a scalar or pseudo-scalar particle. The final result of the BR(K+→π+νν¯ ) measurement and its interpretation in terms of the K+→π+X decay from the analysis of the full 2016-2018 data set is presented, and future plans and prospects are reviewed

AFFECTIVE COMPUTING IN SMART EDUCATION: Stato dell'Arte e Sviluppo di un Prototipo

Lo sviluppo negli ultimi anni della tecnologia ed in particolar modo dell'intelligenza artificiale è stato decisamente elevato, ed ha consentito lo sviluppo di molte applicazioni in mercati verticali differenti. In questa tesi, si approfondisce una sotto-categoria dell'IA, ossia l'Affective Computing, il cui ruolo è sviluppare sistemi capaci di riconoscere e simulare le emozioni e gli stati d'animo umani. Questo elaborato fornisce una rassegna dello stato dell'arte dell'Affective Computing, e ne descrive inoltre una possibile applicazione nel dominio della Smart Education. Il progetto consiste nella lettura del flusso di un video per vedere i cambiamenti nelle espressioni facciali di un volto, al fine di rilevare le emozioni provate da una persona in determinati momenti e associarle alle espressioni. Infine verrà fornito un report contenente i valori medi di tutte le emozioni rilevate

Anterior cruciate ligament reconstruction and rehabilitation: predictors of functional outcome

Surgical reconstruction of an injured anterior cruciate ligament (ACL) leads to full recovery of function and sports activity in a high percentage of cases. The aim of the present study was to analyze variables related to the patient, the surgical technique and the post-surgical rehabilitation methods, seeking to identify predictors of outcome and recovery time after ACL reconstruction. One hundred and four patients (81 M, 23 F) undergoing a step-based rehabilitation protocol after ACL reconstruction were evaluated. 43.2% of them had an isolated ACL lesion, whereas 56.8% had one or more concurrent injuries. Data relating to personal characteristics, surgery and post-operative management were collected and analyzed for correlation. Clinical outcome was evaluated with IKDC subjective score and the Tegner score, and the time to reach full recovery was noted as well. Young patients with a higher pre-injury Tegner activity level or who practice sport at professional level, no concurrent capsular lesions and no postoperative knee bracing had better clinical results and took shorter time to recover. Also, a higher percentage of on-the-field rehabilitation sessions, and absence of significant muscle strength deficits at the first knee isokinetic test emerged as rehabilitation-related factors leading to a better post-surgical outcome. Personal, surgical and rehabilitation factors should be considered in order to optimize patient management and maximize the expected results. Further studies are needed to find the strongest factors in different patients. LEVEL OF EVIDENCE: Level IV, retrospective study

Anterior cruciate ligament reconstruction and rehabilitation: predictors of functional outcome

Surgical reconstruction of an injured anterior cruciate ligament (ACL) leads to full recovery of function and sports activity in a high percentage of cases. The aim of the present study was to analyze variables related to the patient, the surgical technique and the post-surgical rehabilitation methods, seeking to identify predictors of outcome and recovery time after ACL reconstruction. One hundred and four patients (81 M, 23 F) undergoing a step-based rehabilitation protocol after ACL reconstruction were evaluated. 43.2% of them had an isolated ACL lesion, whereas 56.8% had one or more concurrent injuries. Data relating to personal characteristics, surgery and post-operative management were collected and analyzed for correlation. Clinical outcome was evaluated with IKDC subjective score and the Tegner score, and the time to reach full recovery was noted as well. Young patients with a higher pre-injury Tegner activity level or who practice sport at professional level, no concurrent capsular lesions and no postoperative knee bracing had better clinical results and took shorter time to recover. Also, a higher percentage of on-the-field rehabilitation sessions, and absence of significant muscle strength deficits at the first knee isokinetic test emerged as rehabilitation-related factors leading to a better post-surgical outcome. Personal, surgical and rehabilitation factors should be considered in order to optimize patient management and maximize the expected results. Further studies are needed to find the strongest factors in different patients

Compliance in post\u2011operative rehabilitation is a key factor for return to sport after revision anterior cruciate ligament reconstruction

Abstract Purpose To assess the rate of return to sport (RTS) following revision Anterior Cruciate Ligament Reconstruction (ACLR) in a rehabilitation-based cohort of patients. A secondary goal of the study was to evaluate the association between compliance in post-operative rehabilitation and RTS rate. Methods The study cohort included 79 sport-active patients (62 males, 17 females, 30.0 \ub1 10.2 years old) who underwent revision ACLR surgery and followed the same functional-oriented rehabilitation protocol. Patients were evaluated using a RTS survey: return to any kind of sport participation, return to the same pre-injury sport, return to the same sport at the same pre-injury level. With regards to compliance in post-operative rehabilitation, patients were then grouped in (1) Fully Compliant (FC), (2) Moderately Compliant (MC), (3) Scarcely Compliant (SC), and (4) Non-Compliant (NC). Results At an average follow-up of 29 \ub1 12 months, 86% of the patients returned to some kind of sport activity, 62% returned to the same pre-injury sport activity and 59% returned to the same pre-injury level of sport activity. While no surgical aspects were correlated with RTS, higher BMI was found to have a negative influence (p = 0.033). Regardless of the type of sport, compliance significantly affected RTS at the same pre-injury level (p = 0.006): 86% in FC, 67% in MC, 50% in SC, and 45% in NC. For each compliance goal achieved, the probability of RTS increased by 68% (OR = 1.68; p = 0.027). Conclusion RTS at the same pre-injury level after revision ACLR is challenging. A higher compliance in rehabilitation significantly increases the chances of RTS. Level of evidence IV

Analysis of Dental Malocclusion and Neuromotor Control in Young Healthy Subjects through New Evaluation Tools

Abstract: The presence of a correlation between stomatognathic and postural systems has been investigated by different authors trying to identify a possible influence of dental occlusion on body posture and balance. The aim of this study was to evaluate the relationship between dental occlusion and neuromuscular control in a healthy young population using modern evaluation tools. 25 subjects (9 males and 16 females, aged 23 to 44) were evaluated for dental occlusion, particularly in relation to overjet and overbite parameters, anterior and posterior crossbite, scissor bite, mandibular crowding, molar and canine class, and deviation of the median dental line. Neuromotor control was assessed using two different types of stabilometric platforms in both monopodalic and bipodalic equilibriums (Prokin-B and MF-Stability, Tecnobody, Italy). All subjects were evaluated with and without cotton rolls positioned between the upper and lower arches at the premolar level in order to temporarily eliminate any pathological contact. In all 25 subjects, no statistically significant differences were revealed between the evaluations performed with and without cotton rolls in all the analyzed conditions (in static, in dynamics, with open and closed eyes). This study did not find a significant correlation between dental occlusion and neuromuscular control in a young and healthy population

Inflammatory and senescence-associated mediators affect the persistence of humoral response to COVID-19 mRNA vaccination in transfusion-dependent beta-thalassemic patients

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