A hydrodynamic model of an outer hair cell

On the model it is possible to measure the force and the force direction for each individual hair as a function of the flow direction and velocity. Measurements were made at the man flow velocity .01 m/s, which is equivalent to a flow velocity in the real ear of about 1 micrometer/s. The kinematic viscosity of the liquid used in the model was 10,000 times higher than the viscosity of perilymph to attain hydrodynamic equality. Two different geometries for the sterocilia pattern were tested. First the force distribution for a W-shaped sterocilia pattern was recorded. This is the sterocilia pattern found in all real ears. It is found that the forces acting on the hairs are very regular and perpendicular to the legs of the W when the flow is directed from the outside of the W. When the flow is reversed, the forces are not reversed, but are much more irregular. This can eventually explain the half wave rectification of the nerve signals. As a second experiment, the force distribution for a V-shaped sterocilia pattern was recorded. Here the forces were irregular both when the flow was directed into the V and when it was directed against the edge of the V

Reducing Distracted Driving: Regulation and Education to Avert Traffic Injuries and Fatalities

In this article, we consider the legal and policy implications of distracted driving (the tendency of people to use electronic devices while operating a motor vehicle). After reviewing the empirical evidence showing that distracted driving has serious adverse consequences, we discuss the legal basis for governmental interventions to reduce distracted driving. These interventions include laws restricting the use of electronic devices while driving, especially sending text messages. Since drivers have at best a reduced expectation of privacy, these restrictions should easily survive legal challenges. At the same time, it is important to consider the responsibility of automobile manufacturers to improve safety though design changes. We also advocate health education to change social norms to reduce distracted driving

Distribution of enzymes cleaving pyridine nucleotides in animal tissues

A number of enzymes capable of splitting the pyridine nucleotides have been found in animal tissues. A portion of the DPNase (1) that hydrolyzes the nicotinamide ribose bond of DPN and TPN was reported in the microsomes of rat liver (1). The DPN pyrophosphorylase, first described by Kornberg (2), has been found by Hogeboom and Schneider to be largely localized in the nucleus (3). In previous investigations (4) an enzyme from pigeon liver which splits DPNH and not DPN at the pyrophosphate linkage was described. The present communication deals with the intracellular distribution of enzymes from various species that attack the pyridine coenzymes at the pyrophosphate linkage. The distribution and properties of DPNases from different species and tissues will also be presented

A model for the influence of pressure on the bulk modulus and the influence of temperature on the solidification pressure for liquid lubricants

Two pressure chambers, for compression experiments with liquids from zero to 2.2 GPa pressure, are described. The experimentally measured compressions are then compared to theoretical values given by an isothermal model of equation of state recently introduced for solids. The model describes the pressure and bulk modulus as a function of compression for different types of lubricants with a very high accuracy up to the pressure limit of the high pressure chamber used (2.2 GPa). In addition the influence of temperature on static solidification pressure was found to be a simple function of the thermal expansion of the fluid

High-speed motion picture camera experiments of cavitation in dynamically loaded journal bearings

A high-speed camera was used to investigate cavitation in dynamically loaded journal bearings. The length-diameter ratio of the bearing, the speeds of the shaft and bearing, the surface material of the shaft, and the static and dynamic eccentricity of the bearing were varied. The results reveal not only the appearance of gas cavitation, but also the development of previously unsuspected vapor cavitation. It was found that gas cavitation increases with time until, after many hundreds of pressure cycles, there is a constant amount of gas kept in the cavitation zone of the bearing. The gas can have pressures of many times the atmospheric pressure. Vapor cavitation bubbles, on the other hand, collapse at pressures lower than the atmospheric pressure and cannot be transported through a high-pressure zone, nor does the amount of vapor cavitation in a bearing increase with time. Analysis is given to support the experimental findings for both gas and vapor cavitation

Non-Newtonian Fluid Model Incorporated into Elastohydrodynamic Lubrication of Rectangular Contacts

A procedure is outlined for the numerical solution of the complete elastohydrodynamic lubrication of rectangular contacts incorporating a non-Newtonian fluid model. The approach uses a Newtonian model as long as the shear stress is less than a limiting shear stress. If the shear stress exceeds the limiting value, the shear stress is set equal to the limiting value. The numerical solution requires the coupled solution of the pressure, film shape, and fluid rheology equations from the inlet to the outlet. Isothermal and no-side-leakage assumptions were imposed in the analysis. The influence of dimensionless speed, load, materials, and sliding velocity and limiting-shear-strength proportionality constant on dimensionless minimum film thickness was investigated. Fourteen cases were used in obtaining the minimum-film-thickness equation for an elastohydrodynamically lubricated rectangular contact incorporating a non-Newtonian fluid model. Computer plots are also presented that indicate in detail pressure distribution, film shape, shear stress at the surfaces, and flow throughout the conjunction

Vapor Cavitation in Dynamically Loaded Journal Bearings

High speed motion camera experiments were performed on dynamically loaded journal bearings. The length to diameter ratio of the bearing, the speed of the roller and the tube, the surface material of the roller, and the static and dynamic eccentricity of the bearing were varied. One hundred and thirty-four cases were filmed. The occurrence of vapor cavitation was clearly evident in the films and figures presented. Vapor cavitation was found to occur when the tensile stress applied to the oil exceeded the tensile strength of the oil or the binding of the oil to the surface. The physical situation in which vapor cavitation occurs is during the squeezing and sliding motion within a bearing. Besides being able to accurately capture the vapor cavitation on film, an analysis of the formation and collapse of the cavitation bubbles and characteristics of the bubble content are presented

Elastohydrodynamic lubrication of rectangular contacts

An isothermal elastohydrodynamically lubricated rectangular contact was evaluated numerically. This required the simultaneous solution of the elasticity and Reynolds equations. In the elasticity analysis the contact zone was divided into equal rectangular areas, and it was assumed that a uniform pressure was applied over each area. The elastohydrodynamic lubrication theory thus developed was used to investigate the influence of the dimensionless speed, load, and materials parameters on minimum film thickness. Ten cases were used in obtaining the minimum film thickness formula. Plots are shown that indicate the details of the pressure distribution, film shape, and flow. The characteristic pressure spike is clearly in evidence as is the parallel film shape through the central portion of the contact, with a minimum film thickness occurring near the outlet of the contact

A cooled telescope for infrared balloon astronomy

The characteristics of a 16 inch liquid helium cooled Cassegrain telescope with vibrating secondary mirror are discussed. The telescope is used in making far infrared astronomical observations. The system houses several different detectors for multicolor photometry. The cooled telescope has a ten to one increase in signal-to-noise ratio over a similar warm version and is installed in a high altitude balloon gondola to obtain data on the H2 region of the galaxy

Measurement of the Density of Base Fluids at Pressures 0.422 to 2.20 Gpa

The influence of pressure on the density of six base fluids is experimentally studied for a range of pressures from 0.422 to 2.20 GPa. An important parameter used to describe the results is the change in relative volume with change in pressure dv sub r/dp. For pressures less than the solidification pressure (p ps) a small change in pressure results in a large change in dv sub r/ps. For pressures greater than the solidification pressure (p ps) there is no change in dv sub r/dp with changing pressure. The solidification pressures of the base fluids varies considerably, as do the slopes that the experimental data assumes for p ps. A new formula is developed that describes the effect of pressure on density in terms of four constants. These constants vary for the different base fluids tested