5 research outputs found

    1-(Adamantan-1-ylcarbon­yl)-3-(2,6-difluoro-4-hy­droxy­phen­yl)thio­urea

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    In the title mol­ecule, C18H20F2N2O2S, the 2,6-difluoro-4-hy­droxy­phenyl ring and the carbonyl­thio­urea group are each essentially planar, with maximum deviations of atoms from their mean planes of 0.0113 (14) and 0.1017 (15) Å, respectively; the dihedral angle between these two planes is 71.03 (6)°. An intra­molecular N—H⋯O hydrogen bond occurs. In the crystal, N—H⋯O and O—H⋯S hydrogen bonds connect the mol­ecules into chains running diagonally across the bc plane. C—H⋯S and C—H⋯F contacts are also observed

    A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

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    4-Chloro-N'-[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]benzohydrazide

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    In the title compound, C15H10ClN3O2, the benzene ring is slightly twisted out of the plane of the 2,3-dihydro-1H-indole ring system (r.m.s. deviation = 0.007 (A) over circle), forming a dihedral angle of 7.4 (3)degrees. An intramolecular N-H center dot center dot center dot O hydrogen bond forms a six-membered ring. In the crystal, molecules are linked via N-H center dot center dot center dot O and C-H center dot center dot center dot O hydrogen bonds, forming layers alternately perpendicular to [011] and [011]

    4-Chloro- N

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    In the title compound, C(15)H(10)ClN(3)O(2), the benzene ring is slightly twisted out of the plane of the 2,3-di­hydro-1H-indole ring system (r.m.s. deviation = 0.007 Å), forming a dihedral angle of 7.4 (3)°. An intra­molecular N—H⋯O hydrogen bond forms a six-membered ring. In the crystal, mol­ecules are linked via N—H⋯O and C—H⋯O hydrogen bonds, forming layers alternately perpendicular to [011] and [0-11]
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