24 research outputs found

    Cause of Chirality Consensus

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    Biological macromolecules, proteins and nucleic acids are composed exclusively of chirally pure monomers. The chirality consensus appears vital for life and it has even been considered as a prerequisite of life. However the primary cause for the ubiquitous handedness has remained obscure. We propose that the chirality consensus is a kinetic consequence that follows from the principle of increasing entropy, i.e. the 2nd law of thermodynamics. Entropy increases when an open system evolves by decreasing gradients in free energy with more and more efficient mechanisms of energy transduction. The rate of entropy increase is the universal fitness criterion of natural selection that favors diverse functional molecules and drives the system to the chirality consensus to attain and maintain high-entropy non-equilibrium states.Comment: 8 pages, 2 figure

    Työelämä pelissä : Tietoa rahapelihaittojen tunnistamisesta ja ehkäisemisestä työyhteisössä

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    Työelämä p€lissä. Pelihaitat - tukiaineisto.Tämän vanhan painoksen korvaa uusi, muutettu painos osoitteessa: http://urn.fi/URN:ISBN:978-952-343-620-6</a

    Työelämä pelissä: tietoa rahapelihaittojen tunnistamisesta ja ehkäisemisestä työyhteisössä.

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    Stödmaterial - spelproblemDetta är en gammal upplaga. Den nya, ersättande upplagan finns på adressen: http://urn.fi/URN:ISBN:978-952-343-675-6</a

    Työelämä pelissä: tietoa rahapelihaittojen tunnistamisesta ja ehkäisemisestä työyhteisössä.

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    Stödmaterial - spelproblemDetta är en gammal upplaga. Den nya, ersättande upplagan finns på adressen: http://urn.fi/URN:ISBN:978-952-343-675-6</a

    Saimaannorpan suojeluun liittyvien asenteiden kehitys vuosina 2013–2018 ja Saimaannorppa Life -hankkeen vaikutukset asenneilmapiirin muutokseen

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    Yksi Saimaannorppa LIFE -hankkeen tavoitteista on ollut kuvata saimaannorppaan ja sen suojeluun liittyvien asenteiden kehitystä yhtäältä pitkällä aikavälillä 1900-luvun alusta 2000-luvun alkuun ja toisaalta hankkeen aikana vuosina 2011–2016. Jälkimmäisen jakson aikana erityisen kiinnostuksen kohteena on ollut LIFE-hankkeen käytännön toimenpiteiden vaikutus mahdollisiin asenneilmapiirin muutoksiin. Käsillä oleva raportti on jatkoa vuonna 2014 valmistuneelle, pitkän aikavälin kehitystä ja vuosien 2011–2013 asenneilmapiiriä käsitelleelle, saman tutkimusryhmän raportille. Kummankin raportin tutkimusaineiston ovat muodostaneet paikallisen sanomalehden Itä-Savon ja kansallisen median Helsingin Sanomien sanomalehtikirjoitukset sekä hankkeen tunnistamien eri sidosryhmien edustajien haastattelut. Saatuja tuloksia on verrattu saimaannorppaa koskevaan muuhun tutkimuskirjallisuuteen. Tässä raportissa tarkastellaan asennemuutosta vuosien 2011–2012 aineistosta vuosien 2015–2016 uuteen aineistoon. Tutkimusaineisto on koostunut 357 sanomalehtiartikkelista (joista yli 86 % Itä-Savossa) ja 29 puolistrukturoidusta haastattelusta

    Bacteriophages fEV-1 and fD1 Infect Yersinia pestis

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    Bacteriophages vB_YpeM_fEV-1 (fEV-1) and vB_YpeM_fD1 (fD1) were isolated from incoming sewage water samples in Turku, Finland, using Yersinia pestis strains EV76 and KIM D27 as enrichment hosts, respectively. Genomic analysis and transmission electron microscopy established that fEV-1 is a novel type of dwarf myovirus, while fD1 is a T4-like myovirus. The genome sizes are 38 and 167 kb, respectively. To date, the morphology and genome sequences of some dwarf myoviruses have been described; however, a proteome characterization such as the one presented here, has currently been lacking for this group of viruses. Notably, fEV-1 is the first dwarf myovirus described for Y. pestis. The host range of fEV-1 was restricted strictly to Y. pestis strains, while that of fD1 also included other members of Enterobacterales such as Escherichia coli and Yersinia pseudotuberculosis. In this study, we present the life cycles, genomes, and proteomes of two Yersinia myoviruses, fEV-1 and fD1

    Bacteriophages fEV-1 and fD1 Infect Yersinia pestis

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    Bacteriophages vB_YpeM_fEV-1 (fEV-1) and vB_YpeM_fD1 (fD1) were isolated from incoming sewage water samples in Turku, Finland, using Yersinia pestis strains EV76 and KIM D27 as enrichment hosts, respectively. Genomic analysis and transmission electron microscopy established that fEV-1 is a novel type of dwarf myovirus, while fD1 is a T4-like myovirus. The genome sizes are 38 and 167 kb, respectively. To date, the morphology and genome sequences of some dwarf myoviruses have been described; however, a proteome characterization such as the one presented here, has currently been lacking for this group of viruses. Notably, fEV-1 is the first dwarf myovirus described for Y. pestis. The host range of fEV-1 was restricted strictly to Y. pestis strains, while that of fD1 also included other members of Enterobacterales such as Escherichia coli and Yersinia pseudotuberculosis. In this study, we present the life cycles, genomes, and proteomes of two Yersinia myoviruses, fEV-1 and fD1

    Bacteriophages fev-1 and fd1 infect yersinia pestis

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    Bacteriophages vB_YpeM_fEV-1 (fEV-1) and vB_YpeM_fD1 (fD1) were isolated from incoming sewage water samples in Turku, Finland, using Yersinia pestis strains EV76 and KIM D27 as enrichment hosts, respectively. Genomic analysis and transmission electron microscopy established that fEV-1 is a novel type of dwarf myovirus, while fD1 is a T4-like myovirus. The genome sizes are 38 and 167 kb, respectively. To date, the morphology and genome sequences of some dwarf myoviruses have been described; however, a proteome characterization such as the one presented here, has currently been lacking for this group of viruses. Notably, fEV-1 is the first dwarf myovirus described for Y. pestis. The host range of fEV-1 was restricted strictly to Y. pestis strains, while that of fD1 also included other members of Enterobacterales such as Escherichia coli and Yersinia pseudotuberculosis. In this study, we present the life cycles, genomes, and proteomes of two Yersinia myoviruses, fEV-1 and fD1</p
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