Exchange-Rate Economics for the Resources Sector

The paper provides an account of aspects of exchange-rate economics that are of particular relevance to the resources sector. The issues discussed include exchange-rate volatility and risk management practices used to deal with it, the role of productivity differences across countries, the impact of a booming resources sector on the country’s exchange rate and approaches to forecasting exchange rates. The discussion is organised around a simple stylised model that emphasises the quantity theory of money and purchasing power parity as a long-run link between prices and exchange rates.

The church as a local organisation : a comparative case study in the sociology of organisations

This thesis uses a comparative case study as the means for demonstrating how the policies and attitudes of local churches are influenced by organisational factors. A model based on open systems theory reveals that each local church mediates and processes a variety of environmental inputs. As a result, the inputs are converted into outputs or products. The model, therefore, draws attention to the relationship between the churches and their environment and also to their internal structures and processes. In this instance a single input was followed through 'the system'. This concerned the question of the response of local churches to high levels of unemployment, and associated socio-political issues. The resultant data underlines how important for these churches is their 'religious' environment, particularly when it involves their parent denominations. The main finding, however, is that the two churches investigated were both able to mediate and modify environmental inputs on unemployment. It is, therefore, the 'internal' polities and organisational structures of local churches which are of prime importance. Despite the fact that these churches had different polities, it was possible to discern in each case the key interaction between formal and informal organisational structures and processes, and how these related to the position and activities of agents such as the minister and lay leaders. It was found, in more specific terms, that the most crucial influence on the internal processes of these churches came from the ministers. The investigation required a fourteen-month period of intensive fieldwork during which the writer was a participant observer in both churches. Other methods of data collection used included both structured and unstructured interviews and the monitoring and analysis of a wide range of secondary material. The findings presented here are a contribution to both the sociology of organisations and the sociology of religion. They also illustrate the value of ethnographic studies of the church in its manifestation as a local organisation

Higher Education Exchange: 2007

This annual publication serves as a forum for new ideas and dialogue between scholars and the larger public. Essays explore ways that students, administrators, and faculty can initiate and sustain an ongoing conversation about the public life they share.The Higher Education Exchange is founded on a thought articulated by Thomas Jefferson in 1820: "I know no safe depository of the ultimate powers of the society but the people themselves; and if we think them not enlightened enough to exercise their control with a wholesome discretion, the remedy is not to take it from them, but to inform their discretion by education."In the tradition of Jefferson, the Higher Education Exchange agrees that a central goal of higher education is to help make democracy possible by preparing citizens for public life. The Higher Education Exchange is part of a movement to strengthen higher education's democratic mission and foster a more democratic culture throughout American society.Working in this tradition, the Higher Education Exchange publishes interviews, case studies, analyses, news, and ideas about efforts within higher education to develop more democratic societies

Long-Term Isothermal Aging Effects on Carbon Fabric-Reinforced PMR-15 Composites: Compression Strength

A study was conducted to determine the effects of long-term isothermal thermo-oxidative aging on the compressive properties of T-650-35 fabric reinforced PMR-15 composites. The temperatures that were studied were 204, 260, 288, 316, and 343 C. Specimens of different geometries were evaluated. Cut edge-to-surface ratios of 0.03 to 0.89 were fabricated and aged. Aging times extended to a period in excess of 15,000 hours for the lower temperature runs. The unaged and aged specimens were tested in compression in accordance with ASTM D-695. Both thin and thick (plasma) specimens were tested. Three specimens were tested at each time/temperature/geometry condition. The failure modes appeared to be initiated by fiber kinking with longitudinal, interlaminar splitting. In general, it appears that the thermo-oxidative degradation of the compression strength of the composite material may occur by both thermal (time-dependent) and oxidative (weight-loss) mechanisms. Both mechanisms appear to be specimen-thickness dependent

Extensive DNA mimicry by the ArdA anti-restriction protein and its role in the spread of antibiotic resistance

The ardA gene, found in many prokaryotes including important pathogenic species, allows associated mobile genetic elements to evade the ubiquitous Type I DNA restriction systems and thereby assist the spread of resistance genes in bacterial populations. As such, ardA contributes to a major healthcare problem. We have solved the structure of the ArdA protein from the conjugative transposon Tn916 and find that it has a novel extremely elongated curved cylindrical structure with defined helical grooves. The high density of aspartate and glutamate residues on the surface follow a helical pattern and the whole protein mimics a 42-base pair stretch of B-form DNA making ArdA by far the largest DNA mimic known. Each monomer of this dimeric structure comprises three alpha–beta domains, each with a different fold. These domains have the same fold as previously determined proteins possessing entirely different functions. This DNA mimicry explains how ArdA can bind and inhibit the Type I restriction enzymes and we demonstrate that 6 different ardA from pathogenic bacteria can function in Escherichia coli hosting a range of different Type I restriction systems

Haptoglobin Phenotype, Preeclampsia Risk and the Efficacy of Vitamin C and E Supplementation to Prevent Preeclampsia in a Racially Diverse Population

Haptoglobin's (Hp) antioxidant and pro-angiogenic properties differ between the 1-1, 2-1, and 2-2 phenotypes. Hp phenotype affects cardiovascular disease risk and treatment response to antioxidant vitamins in some non-pregnant populations. We previously demonstrated that preeclampsia risk was doubled in white Hp 2-1 women, compared to Hp 1-1 women. Our objectives were to determine whether we could reproduce this finding in a larger cohort, and to determine whether Hp phenotype influences lack of efficacy of antioxidant vitamins in preventing preeclampsia and serious complications of pregnancy-associated hypertension (PAH). This is a secondary analysis of a randomized controlled trial in which 10,154 low-risk women received daily vitamin C and E, or placebo, from 9-16 weeks gestation until delivery. Hp phenotype was determined in the study prediction cohort (n = 2,393) and a case-control cohort (703 cases, 1,406 controls). The primary outcome was severe PAH, or mild or severe PAH with elevated liver enzymes, elevated serum creatinine, thrombocytopenia, eclampsia, fetal growth restriction, medically indicated preterm birth or perinatal death. Preeclampsia was a secondary outcome. Odds ratios were estimated by logistic regression. Sampling weights were used to reduce bias from an overrepresentation of women with preeclampsia or the primary outcome. There was no relationship between Hp phenotype and the primary outcome or preeclampsia in Hispanic, white/other or black women. Vitamin supplementation did not reduce the risk of the primary outcome or preeclampsia in women of any phenotype. Supplementation increased preeclampsia risk (odds ratio 3.30; 95% confidence interval 1.61-6.82, p<0.01) in Hispanic Hp 2-2 women. Hp phenotype does not influence preeclampsia risk, or identify a subset of women who may benefit from vitamin C and E supplementation to prevent preeclampsia

The Molloy Student Literary Magazine Volume 10

The Molloy Student Literary Magazine, sponsored by Molloy College’s Office of Student Affairs, is devoted to publishing the best previously unpublished works of prose, poetry, drama, literary review, criticism, and other literary genres, that the Molloy student community has to offer. The journal welcomes submissions, for possible publication, from currently enrolled Molloy students at all levels. All submitted work will undergo a review process initiated by the Managing Editor prior to a decision being made regarding publication of said work. Given sufficient content, The Molloy Student Literary Magazine is published twice annually in Spring and Fall. Interested contributors from the currently enrolled Molloy student community should send work via e-mail attachment and brief cover letter (including a two-sentence biographical statement) to: Dr. Damian Ward Hey, Managing Editor, The Molloy Student Literary Magazine: [email protected]. Enrolled students who are interested in becoming members of The Molloy Student Literary Magazine staff may e-mail letters of inquiry. Excelsior!https://digitalcommons.molloy.edu/eng_litmag/1002/thumbnail.jp

IM Normae: The Death Spiral of a Cataclysmic Variable?

We present a study of the orbital light curves of the recurrent nova IM Normae since its 2002 outburst. The broad "eclipses" recur with a 2.46 hour period, which increases on a timescale of 1.28(16)x10^6 years. Under the assumption of conservative mass-transfer, this suggests a rate near 10^-7 M_sol/year, and this agrees with the estimated /accretion/ rate of the postnova, based on our estimate of luminosity. IM Nor appears to be a close match to the famous recurrent nova T Pyxidis. Both stars appear to have very high accretion rates, sufficient to drive the recurrent-nova events. Both have quiescent light curves which suggest strong heating of the low-mass secondary, and very wide orbital minima which suggest obscuration of a large "corona" around the primary. And both have very rapid orbital period increases, as expected from a short-period binary with high mass transfer from the low-mass component. These two stars may represent a final stage of nova -- and cataclysmic-variable -- evolution, in which irradiation-driven winds drive a high rate of mass transfer, thereby evaporating the donor star in a paroxysm of nova outbursts.Comment: PDF, 30 pages, 3 tables, 6 figures; accepted, in press, ApJ; more info at http://cbastro.org

Specific strains of Escherichia coli are pathogenic for the endometrium of cattle and cause pelvic inflammatory disease in cattle and mice.

BACKGROUND: Escherichia coli are widespread in the environment and pathogenic strains cause diseases of mucosal surfaces including the female genital tract. Pelvic inflammatory disease (PID; metritis) or endometritis affects ∼40% of cattle after parturition. We tested the expectation that multiple genetically diverse E. coli from the environment opportunistically contaminate the uterine lumen after parturition to establish PID. METHODOLOGY/PRINCIPAL FINDINGS: Distinct clonal groups of E. coli were identified by Random Amplification of Polymorphic DNA (RAPD) and Multilocus sequence typing (MLST) from animals with uterine disease and these differed from known diarrhoeic or extra-intestinal pathogenic E. coli. The endometrial pathogenic E. coli (EnPEC) were more adherent and invasive for endometrial epithelial and stromal cells, compared with E. coli isolated from the uterus of clinically unaffected animals. The endometrial epithelial and stromal cells produced more prostaglandin E(2) and interleukin-8 in response to lipopolysaccharide (LPS) purified from EnPEC compared with non-pathogenic E. coli. The EnPEC or their LPS also caused PID when infused into the uterus of mice with accumulation of neutrophils and macrophages in the endometrium. Infusion of EnPEC was only associated with bacterial invasion of the endometrium and myometrium. Despite their ability to invade cultured cells, elicit host cell responses and establish PID, EnPEC lacked sixteen genes commonly associated with adhesion and invasion by enteric or extraintestinal pathogenic E. coli, though the ferric yersiniabactin uptake gene (fyuA) was present in PID-associated EnPEC. Endometrial epithelial or stromal cells from wild type but not Toll-like receptor 4 (TLR4) null mice secreted prostaglandin E(2) and chemokine (C-X-C motif) ligand 1 (CXCL1) in response to LPS from EnPEC, highlighting the key role of LPS in PID. CONCLUSIONS/SIGNIFICANCE: The implication arising from the discovery of EnPEC is that development of treatments or vaccines for PID should focus specifically on EnPEC and not other strains of E. coli