Cosmology in a brane-universe

This contribution presents the cosmological models with extra dimensions that have been recently elaborated, which assume that ordinary matter is confined on a surface, called brane, embedded in a higher dimensional spacetime.Comment: 12 pages; Invited review talk at the JENAM 2002 workshop on "The cosmology of extra dimensions and varying fundamental constants", Porto, Portugal, September 200

Status of Electroweak Phase Transition and Baryogenesis

I review recent progress on the electroweak phase transition and baryogenesis, focusing on the minimal supersymmetric standard model as the source of new physics.Comment: 10 pp, 6 figures; plenary talk given at 6th Workshop on High Energy Physics Phenomenology, 4 Jan. 2000, Chennai, India. v.2: added reference

Lorentz-violating vs ghost gravitons: the example of Weyl gravity

We show that the ghost degrees of freedom of Einstein gravity with a Weyl term can be eliminated by a simple mechanism that invokes local Lorentz symmetry breaking. We demonstrate how the mechanism works in a cosmological setting. The presence of the Weyl term forces a redefinition of the quantum vacuum state of the tensor perturbations. As a consequence the amplitude of their spectrum blows up when the Lorentz-violating scale becomes comparable to the Hubble radius. Such a behaviour is in sharp contrast to what happens in standard Weyl gravity where the gravitational ghosts smoothly damp out the spectrum of primordial gravitational waves.Comment: 14 pages, 3 figures, REVTeX 4.

The Light Stop Scenario from Gauge Mediation

In this paper we embed the light stop scenario, a MSSM framework which explains the baryon asymmetry of the universe through a strong first order electroweak phase transition, in a top-down approach. The required low energy spectrum consists in the light SM-like Higgs, the right-handed stop, the gauginos and the Higgsinos while the remaining scalars are heavy. This spectrum is naturally driven by renormalization group evolution starting from a heavy scalar spectrum at high energies. The latter is obtained through a supersymmetry-breaking mix of gauge mediation, which provides the scalars masses by new gauge interactions, and gravity mediation, which generates gaugino and Higgsino masses. This supersymmetry breaking also explains the \mu\ and B_\mu\ parameters necessary for electroweak breaking and predicts small tri-linear mixing terms A_t in agreement with electroweak baryogenesis requirements. The minimal embedding predicts a Higgs mass around its experimental lower bound and by a small extension higher masses m_H\lesssim 127 GeV can be accommodated.Comment: 20 pages, 3 figures; v2: changes in the conventions; v3: more details on the Higgs mass prediction, version published in JHE

Excluding Electroweak Baryogenesis in the MSSM

In the context of the MSSM the Light Stop Scenario (LSS) is the only region of parameter space that allows for successful Electroweak Baryogenesis (EWBG). This possibility is very phenomenologically attractive, since it allows for the direct production of light stops and could be tested at the LHC. The ATLAS and CMS experiments have recently supplied tantalizing hints for a Higgs boson with a mass of ~ 125 GeV. This Higgs mass severely restricts the parameter space of the LSS, and we discuss the specific predictions made for EWBG in the MSSM. Combining data from all the available ATLAS and CMS Higgs searches reveals a tension with the predictions of EWBG even at this early stage. This allows us to exclude EWBG in the MSSM at greater than (90) 95% confidence level in the (non-)decoupling limit, by examining correlations between different Higgs decay channels. We also examine the exclusion without the assumption of a ~ 125 GeV Higgs. The Higgs searches are still highly constraining, excluding the entire EWBG parameter space at greater than 90% CL except for a small window of m_h ~ 117 - 119 GeV.Comment: 24 Pages, 4 Figures (v3: fixed typos, minor corrections, added references

Interplay between Fermi gamma-ray lines and collider searches

We explore the interplay between lines in the gamma-ray spectrum and LHC searches involving missing energy and photons. As an example, we consider a singlet Dirac fermion dark matter with the mediator for Fermi gamma-ray line at 130 GeV. A new chiral or local U(1) symmetry makes weak-scale dark matter natural and provides the axion or Z 0 gauge boson as the mediator connecting between dark matter and electroweak gauge bosons. In these models, the mediator particle can be produced in association with a monophoton at colliders and it produces large missing energy through the decays into a DM pair or ZZ; Z with at least one Z decaying into a neutrino pair. We adopt the monophoton searches with large missing energy at the LHC and impose the bounds on the coupling and mass of the mediator field in the models. We show that the parameter space of the Z 0 mediation model is already strongly constrained by the LHC 8TeV data, whereas a certain region of the parameter space away from the resonance in axion-like mediator models are bounded. We foresee the monophoton bounds on the Z 0 and axion mediation models at the LHC 14 TeV

Weekly paclitaxel, gemcitabine, and external irradiation followed by randomized farnesyl transferase inhibitor R115777 for locally advanced pancreatic cancer.

PURPOSE: The Radiation Therapy Oncology Group (RTOG) multi-institutional Phase II study 98-12, evaluating paclitaxel and concurrent radiation (RT) for locally advanced pancreatic cancer, demonstrated a median survival of 11.3 months and a 1-year survival of 43%. The purpose of the randomized Phase II study by RTOG 0020 was to evaluate the addition of weekly low- dose gemcitabine with concurrent paclitaxel/RT and to evaluate the efficacy and safety of the farnesyl transferase inhibitor R115777 following chemoradiation. PATIENTS AND METHODS: Patients with unresectable, nonmetastatic adenocarcinoma of the pancreas were eligible. Patients in Arm 1 received gemcitabine, 75 mg/m(2)/week, and paclitaxel, 40 mg/m(2)/week, for 6 weeks, with 50.4 Gy radiation (CXRT). Patients in Arm 2 received an identical chemoradiation regimen but then received maintenance R115777, 300 mg twice a day for 21 days every 28 days (CXRT+R115777), until disease progression or unacceptable toxicity. RESULTS: One hundred ninety-five patients were entered into this study, and 184 were analyzable. Grade 4 nonhematologic toxicities occurred in less than 5% of CXRT patients. The most common grade 3/4 toxicity from R115777 was myelosuppression; however, grade 3/4 hepatic, metabolic, musculoskeletal, and neurologic toxicities were also reported. The median survival time was 11.5 months and 8.9 months for the CXRT and CXRT+R115777 arms, respectively. CONCLUSIONS: The CXRT arm achieved a median survival of almost 1-year, supporting chemoradiation as an important therapeutic modality for locally advanced pancreatic cancer. Maintenance R115777 is not effective and is associated with a broad range of toxicities. These findings provide clinical evidence that inhibition of farnesylation affects many metabolic pathways, underscoring the challenge of developing an effective K-ras inhibitor

Massive Gravity: Exorcising the Ghost

We consider Higgs massive gravity [1,2] and investigate whether a nonlinear ghost in this theory can be avoided. We show that although the theory considered in [10,11] is ghost free in the decoupling limit, the ghost nevertheless reappears in the fourth order away from the decoupling limit. We also demonstrate that there is no direct relation between the value of the Vainshtein scale and the existence of nonlinear ghost. We discuss how massive gravity should be modified to avoid the appearance of the ghost.Comment: 16 page

Flavour-coherent propagators and Feynman rules: Covariant cQPA formulation

We present a simplified and generalized derivation of the flavour-coherent propagators and Feynman rules for the fermionic kinetic theory based on coherent quasiparticle approximation (cQPA). The new formulation immediately reveals the composite nature of the cQPA Wightman function as a product of two spectral functions and an effective two-point interaction vertex, which contains all quantum statistical and coherence information. We extend our previous work to the case of nonzero dispersive self-energy, which leads to a broader range of applications. By this scheme, we derive flavoured kinetic equations for local 2-point functions $S^{}_\mathbf{k}(t,t)$, which are reminiscent of the equations of motion for the density matrix. We emphasize that in our approach all the interaction terms are derived from first principles of nonequilibrium quantum field theory.Comment: 20 pages, 3 figures. Minor modifications, version published in JHE

Gamma Lines without a Continuum: Thermal Models for the Fermi-LAT 130 GeV Gamma Line

Recent claims of a line in the Fermi-LAT photon spectrum at 130 GeV are suggestive of dark matter annihilation in the galactic center and other dark matter-dominated regions. If the Fermi feature is indeed due to dark matter annihilation, the best-fit line cross-section, together with the lack of any corresponding excess in continuum photons, poses an interesting puzzle for models of thermal dark matter: the line cross-section is too large to be generated radiatively from open Standard Model annihilation modes, and too small to provide efficient dark matter annihilation in the early universe. We discuss two mechanisms to solve this puzzle and illustrate each with a simple reference model in which the dominant dark matter annihilation channel is photonic final states. The first mechanism we employ is resonant annihilation, which enhances the annihilation cross-section during freezeout and allows for a sufficiently large present-day annihilation cross section. Second, we consider cascade annihilation, with a hierarchy between p-wave and s-wave processes. Both mechanisms require mass near-degeneracies and predict states with masses closely related to the dark matter mass; resonant freezeout in addition requires new charged particles at the TeV scale.Comment: 17 pages, 8 figure