41 research outputs found
An Approximate Dynamic Programming Approach to Urban Freight Distribution with Batch Arrivals
We study an extension of the delivery dispatching problem (DDP) with time windows, applied on LTL orders arriving at an urban consolidation center. Order properties (e.g., destination, size, dispatch window) may be highly varying, and directly distributing an incoming order batch may yield high costs. Instead, the hub operator may wait to consolidate with future arrivals. A consolidation policy is required to decide which orders to ship and which orders to hold. We model the dispatching problem as a Markov decision problem. Dynamic Programming (DP) is applied to solve toy-sized instances to optimality. For larger instances, we propose an Approximate Dynamic Programming (ADP) approach. Through numerical experiments, we show that ADP closely approximates the optimal values for small instances, and outperforms two myopic benchmark policies for larger instances. We contribute to literature by (i) formulating a DDP with dispatch windows and (ii) proposing an approach to solve this DDP
Scheduling internal audit activities:A stochastic combinatorial optimization problem
The problem of finding the optimal timing of audit activities within an organisation has been addressed by many researchers. We propose a stochastic programming formulation with Mixed Integer Linear Programming (MILP) and Constraint Programming (CP) certainty-equivalent models. In experiments neither approach dominates the other. However, the CP approach is orders of magnitude faster for large audit times, and almost as fast as the MILP approach for small audit times. This work generalises a previous approach by relaxing the assumption of instantaneous audits, and by prohibiting concurrent auditin
What is the value and impact of quality and safety teams? A scoping review
<p>Abstract</p> <p>Background</p> <p>The purpose of this study was to conduct a scoping review of the literature about the establishment and impact of quality and safety team initiatives in acute care.</p> <p>Methods</p> <p>Studies were identified through electronic searches of Medline, Embase, CINAHL, PsycINFO, ABI Inform, Cochrane databases. Grey literature and bibliographies were also searched. Qualitative or quantitative studies that occurred in acute care, describing how quality and safety teams were established or implemented, the impact of teams, or the barriers and/or facilitators of teams were included. Two reviewers independently extracted data on study design, sample, interventions, and outcomes. Quality assessment of full text articles was done independently by two reviewers. Studies were categorized according to dimensions of quality.</p> <p>Results</p> <p>Of 6,674 articles identified, 99 were included in the study. The heterogeneity of studies and results reported precluded quantitative data analyses. Findings revealed limited information about attributes of successful and unsuccessful team initiatives, barriers and facilitators to team initiatives, unique or combined contribution of selected interventions, or how to effectively establish these teams.</p> <p>Conclusions</p> <p>Not unlike systematic reviews of quality improvement collaboratives, this broad review revealed that while teams reported a number of positive results, there are many methodological issues. This study is unique in utilizing traditional quality assessment and more novel methods of quality assessment and reporting of results (SQUIRE) to appraise studies. Rigorous design, evaluation, and reporting of quality and safety team initiatives are required.</p
Arthropod venom Hyaluronidases: biochemical properties and potential applications in medicine and biotechnology
The single-vehicle routing problem with unrestricted backhauls
Suppose that a private carrier delivers to a set of customers and also has a number of (optional) backhaul opportunities. It wants to choose the best of these, depending on the revenue generated, and insert them in a revised tour. This will be at an expense of deviation from the original tour, because, here, deliveries need not precede backhauls. The problem is to find the mixed tour whose net cost is the lowest, selecting the most profitable backhauls subject to the overall capacity. We thus generalize several other vehicle routing problems with backhauls. A mixed-integer model is developed for the problem. It is based on Miller-Tucker-Zemlin subtour elimination constraints. We address several improvement techniques aimed at increasing computational tractability of the formulation. Computational results show that medium-sized problems can be solved optimally in a reasonable time by using a general-purpose commercial solver. (C) 2003 Wiley Periodicals, Inc
The single-vehicle routing problem with unrestricted backhauls
Suppose that a private carrier delivers to a set of customers and also has a number of (optional) backhaul opportunities. It wants to choose the best of these, depending on the revenue generated, and insert them in a revised tour. This will be at an expense of deviation from the original tour, because, here, deliveries need not precede backhauls. The problem is to find the mixed tour whose net cost is the lowest, selecting the most profitable backhauls subject to the overall capacity. We thus generalize several other vehicle routing problems with backhauls. A mixed-integer model is developed for the problem. It is based on Miller-Tucker-Zemlin subtour elimination constraints. We address several improvement techniques aimed at increasing computational tractability of the formulation. Computational results show that medium-sized problems can be solved optimally in a reasonable time by using a general-purpose commercial solver. (C) 2003 Wiley Periodicals, Inc