The first case of Brucella canis in Sweden: background, case report and recommendations from a northern European perspective

Infection with Brucella canis has been diagnosed in Sweden for the first time. It was diagnosed in a three-year-old breeding bitch with reproductive disturbances. Fifteen in-contact dogs were tested repeatedly and all of them were negative for B. canis. The source of infection could not be defined. The present article describes the case and the measures undertaken and gives a short review over B. canis. Recommendations on how to avoid the infection in non-endemic countries are given

Changes in bone marrow lesions in response to weight-loss in obese knee osteoarthritis patients: a prospective cohort study

BACKGROUND: Patients are susceptible for knee osteoarthritis (KOA) with increasing age and obesity and KOA is expected to become a major disabling disease in the future. An important feature of KOA on magnetic resonance imaging (MRI) is changes in the subchondral bone, bone marrow lesions (BMLs), which are related to the future degeneration of the knee joint as well as prevalent clinical symptoms. The aim of this study was to investigate the changes in BMLs after a 16-week weight-loss period in obese subjects with KOA and relate changes in BMLs to the effects of weight-loss on clinical symptoms. METHODS: This prospective cohort study included patients with a body mass index ≥ 30 kg/m(2), an age ≥ 50 years and primary KOA. Patients underwent a 16 weeks supervised diet program which included formula products and dietetic counselling (ClinicalTrials.gov: NCT00655941). BMLs in tibia and femur were assessed on MRI before and after the weight-loss using the Boston-Leeds Osteoarthritis Knee Score. Response to weight-loss in BML scores was dichotomised to patients experiencing a decrease in BML scores (responders) and patients who did not (non-responders). The association of BMLs to weight-loss was assessed by logistic regressions and correlation analyses. RESULTS: 39 patients (23%) were classified as responders in the sum of all BML size scores whereas 130 patients (77%) deteriorated or remained stable and were categorized as non-responders. Logistic regression analyses revealed no association between weight-loss < or ≥ 10% and response in BMLs in the most affected compartment (OR 1.86 [CI 0.66 to 5.26, p=0.24]). There was no association between weight-loss and response in maximum BML score (OR 1.13 [CI 0.39 to 3.28, p=0.81]). The relationship between changes in BMLs and clinical symptoms revealed that an equal proportion of patients classified as BML responders and non-responders experienced an OMERACT-OARSI response (69 vs. 71%, p=0.86). CONCLUSIONS: Weight-loss did not improve the sum of tibiofemoral BML size scores or the maximum tibiofemoral BML score, suggesting that BMLs do not respond to a rapidly decreased body weight. The missing relationship between clinical symptoms and BMLs calls for further investigation

Representing 3D Space in Working Memory: Spatial Images from Vision, Hearing, Touch, and Language

The chapter deals with a form of transient spatial representation referred to as a spatial image. Like a percept, it is externalized, scaled to the environment, and can appear in any direction about the observer. It transcends the concept of modality, as it can be based on inputs from the three spatial senses, from language, and from long-term memory. Evidence is presented that supports each of the claimed properties of the spatial image, showing that it is quite different from a visual image. Much of the evidence presented is based on spatial updating. A major concern is whether spatial images from different input modalities are functionally equivalent— that once instantiated in working memory, the spatial images from different modalities have the same functional characteristics with respect to subsequent processing, such as that involved in spatial updating. Going further, the research provides some evidence that spatial images are amodal (i.e., do not retain modality-specific features)

Cross-cultural adaption of the German Quebec Back Pain Disability Scale: an exposure-specific measurement for back pain patients

Jenny Riecke,1 Sebastian Holzapfel,1 Winfried Rief,1 Harald Lachnit,2 Julia A Glombiewski1 1Department for Clinical Psychology and Psychotherapy, 2Department for Associative Learning, University of Marburg, Marburg, Germany Study design: Cross-cultural translation and psychometric testing. Objective: The purpose of the present study was to examine reliability and validity of a cross-cultural adaption of the German Quebec Back Pain Disability Scale (QBPDS) in a context of a randomized controlled trial evaluating the effectiveness of graded in vivo exposure in chronic low back pain patients. Background: The QBPDS is one of the most widely used disease-specific disability questionnaires. In particular, for cognitive behavioral treatments with a clear focus on behavioral aspects such as graded in vivo exposure, the QBPDS provides an ascertained strategy with a sound conceptual basis and excellent quality criteria. Nevertheless, there is conflicting evidence concerning factor structure and a German adaption is missing. Methods: The cross-cultural adaption followed international guidelines. Psychometric testing was performed using data from 180 participants with chronic low back pain. The psychometric analyses included internal consistency, convergent, and divergent validity. Exploratory factor analysis was used to determine the underlying factor structure. Results: The QBPDS showed strong psychometric properties, with high internal consistency for the full scale (&alpha;=0.94) and good convergent and divergent validity. The factor analysis revealed a four-factor solution (bending, ambulation, brief effortful movements, and long-lasting postures). Conclusion: The translation and cross-cultural adaption of the QBPDS into German was successful. The German version proved to be a valid and reliable instrument and is well suited for use in the context of an exposure-based psychological treatment. Keywords: Chronic pain, back pain, questionnaire, functional disability, German, validatio

Influence of Dynamic Field of View Restrictions on Rotation Gain Perception in Virtual Environments

International audienceThe perception of rotation gain, defined as a modification of the virtual rotation with respect to the real rotation, has been widely studied to determine detection thresholds and widely applied to redirected navigation techniques. In contrast, Field of View (FoV) restrictions have been explored in virtual reality as a mitigation strategy for motion sickness, although they can alter user's perception and navigation performance in virtual environments. This paper explores whether the use of dynamic FoV manipulations, referred also as vignetting, could alter the perception of rotation gains during virtual rotations in virtual environments (VEs). We conducted a study to estimate and compare perceptual thresholds of rotation gains while varying the vignetting type (no vignetting, horizontal and global vignetting) and the vignetting effect (luminance or blur). 24 Participants performed 60 or 90 degrees virtual rotations in a virtual forest, with different rotation gains applied. Participants have to choose whether or not the virtual rotation was greater than the physical one. Results showed that the point of subjective equality was different across the vignetting types, but not across the vignetting effect or the turns. Subjective questionnaires indicated that vignetting seems less comfortable than the baseline condition to perform the task. We discuss the applications of such results to improve the design of vignetting for redirection techniques

Quality of experience and quality of service metrics for 3D content

Traditionally, the quality of a multimedia system was mainly assessed through the evaluation of its Quality of Service (QoS) that is by evaluating system parameters such as bandwidth, latency, jitter, throughput, transmission delay, availability, etc. However, these metrics often failed to capture the actual end-user perceived quality, which has prompted the development of the construct of Quality of Experience (QoE), widely understood as an interaction of the technical features of multimedia systems with perceptual, and cognitive/emotional factors involved in the interpretation of those features by users. This chapter addresses the open issues in the field of QoS and QoE assessments. First, the perceptual characteristics of the multiview content are analyzed, and then a survey on the existing approaches for QoS and QoE estimation is performed. The analysis is then focused on the subjective aspects of QoE assessment, by describing the standard methodologies currently used and new trends based on human factors research. Finally, the chapter offers a few guidelines for future research directions in the field