A free boundary problem modeling electrostatic MEMS: II. nonlinear bending effects

Well-posedness of a free boundary problem for electrostatic microelectromechanical systems (MEMS) is investigated when nonlinear bending effects are taken into account. The model describes the evolution of the deflection of an electrically conductive elastic membrane suspended above a fixed ground plate together with the electrostatic potential in the free domain between the membrane and the fixed ground plate. The electrostatic potential is harmonic in that domain and its values are held fixed along the membrane and the ground plate. The equation for the membrane deflection is a parabolic quasilinear fourth-order equation, which is coupled to the gradient trace of the electrostatic potential on the membrane

The 2019 Mathematical Oncology Roadmap.

Whether the nom de guerre is Mathematical Oncology, Computational or Systems Biology, Theoretical Biology, Evolutionary Oncology, Bioinformatics, or simply Basic Science, there is no denying that mathematics continues to play an increasingly prominent role in cancer research. Mathematical Oncology-defined here simply as the use of mathematics in cancer research-complements and overlaps with a number of other fields that rely on mathematics as a core methodology. As a result, Mathematical Oncology has a broad scope, ranging from theoretical studies to clinical trials designed with mathematical models. This Roadmap differentiates Mathematical Oncology from related fields and demonstrates specific areas of focus within this unique field of research. The dominant theme of this Roadmap is the personalization of medicine through mathematics, modelling, and simulation. This is achieved through the use of patient-specific clinical data to: develop individualized screening strategies to detect cancer earlier; make predictions of response to therapy; design adaptive, patient-specific treatment plans to overcome therapy resistance; and establish domain-specific standards to share model predictions and to make models and simulations reproducible. The cover art for this Roadmap was chosen as an apt metaphor for the beautiful, strange, and evolving relationship between Two Beasts: mathematics and cancer.NIH (R01CA16437, R01NS060752, U54CA210180, U54CA143970, U54193489, U01CA220378)James S. McDonnell FoundationBen & Catherine Ivy Foundatio

Nonlinear Dynamic Problems with Singular Nonlinearities and Applications to MEMS

We establish existence and regularity results for a time dependent fourth order integro-differential equation with a possibly singular nonlinearity which has applications in designing MicroElectroMechanicalSystems. The key ingredient in our approach, besides basic theory of hyperbolic equations in Hilbert spaces, exploits the Near Operators Theory introduced by Campanato

Nonlocal dynamic problems with singular nonlinearities and applications to MEMS

We establish existence and regularity results for a time dependent fourth-order integro-differential equation with a possibly singular nonlinearity which has applications in designing MicroElectroMechanicalSystems. The key ingredient in our approach, besides basic theory of hyperbolic equations in Hilbert spaces, exploits the Near Operators Theory introduced by Campanato

A constrained model for MEMS with varying dielectric properties

International audienceA semilinear parabolic equation with constraint modeling the dynamics of a microelectromechanical system (MEMS) is studied. In contrast to the commonly used MEMS model, the well-known pull-in phenomenon occurring above a critical potential threshold is not accompanied by a breakdown of the model, but is recovered by the saturation of the constraint for pulled-in states. It is shown that a maximal stationary solution exists and that saturation only occurs for large potential values. In addition, the existence, uniqueness, and large time behavior of solutions to the evolution equation are studied