Interpretation of vector-like quark searches: Heavy gluons in composite Higgs models

Pair production of new vector-like quarks in pp collisions is consideredmodelindependentasitisusuallydominatedbyQCDproduction. We discuss the interpretation of vector-like quark searches in the case that QCD is not the only relevant production mechanism for the new quarks. Inparticularweconsidertheeffectofanewmassivecoloroctet vector boson with sizeable decay branching ratio into the new quarks. We pay special attention to the sensitivity of the Large Hadron Collider experiments, both in run-1 and early run-2, to differences in the kinematical distributions from the different production mechanisms. We have found that even though there can be significant differences in some kinematical distributions at the parton level, the differences are washed out at the reconstruction level. Thus, the published experimental results can be reinterpreted in models with heavy gluons by simply rescaling the production cross section.Fundação para a Ciência e Tecnologia (FCT): IF/00050/2013/CP1172/CT0002We would like to thank G. Perez for useful discussions and motivation at the initial stages of this work. JS is supported by MINECO, under grant numbers FPA2010-17915 and FPA2013-47836-C3-2-P, by the European Commission through the contract PITN-GA-2012-316704 (HIGGSTOOLS) and by Junta de Andalucía grants FQM 101 and FQM 6552. JS thanks the Pauli Center Visitor Program for financial support. JPA and NFC are supported by FEDER, COMPETE-QREN and FCT, Portugal, through grant SFRH/BD/52002/2012 (JPA) and contract IF/00050/2013 (NFC)

Towards classical geometrodynamics from Group Field Theory hydrodynamics

We take the first steps towards identifying the hydrodynamics of group field theories (GFTs) and relating this hydrodynamic regime to classical geometrodynamics of continuum space. We apply to GFT mean field theory techniques borrowed from the theory of Bose condensates, alongside standard GFT and spin foam techniques. The mean field configuration we study is, in turn, obtained from loop quantum gravity coherent states. We work in the context of 2d and 3d GFT models, in euclidean signature, both ordinary and colored, as examples of a procedure that has a more general validity. We also extract the effective dynamics of the system around the mean field configurations, and discuss the role of GFT symmetries in going from microscopic to effective dynamics. In the process, we obtain additional insights on the GFT formalism itself.Comment: revtex4, 32 pages. Contribution submitted to the focus issue of the New Journal of Physics on "Classical and Quantum Analogues for Gravitational Phenomena and Related Effects", R. Schuetzhold, U. Leonhardt and C. Maia, Eds; v2: typos corrected, references updated, to match the published versio

Cooperation Survives and Cheating Pays in a Dynamic Network Structure with Unreliable Reputation

In a networked society like ours, reputation is an indispensable tool to guide decisions about social or economic interactions with individuals otherwise unknown. Usually, information about prospective counterparts is incomplete, often being limited to an average success rate. Uncertainty on reputation is further increased by fraud, which is increasingly becoming a cause of concern. To address these issues, we have designed an experiment based on the Prisoner's Dilemma as a model for social interactions. Participants could spend money to have their observable cooperativeness increased. We find that the aggregate cooperation level is practically unchanged, i.e., global behavior does not seem to be affected by unreliable reputations. However, at the individual level we find two distinct types of behavior, one of reliable subjects and one of cheaters, where the latter artificially fake their reputation in almost every interaction.A. A. gratefully acknowledges financial support by the Swiss National Science Foundation (under grants no. 200020-143224, CR13I1-138032 and P2LAP1-161864) and by the Rectors’ Conference of the Swiss Universities (under grant no. 26058983). All authors acknowledge financial support to carry out the experiments by the Faculty of Business and Economics of the University of Lausanne and the fundamental support by Prof. Rafael Lalive. This work has been supported in part by the European Commission through FET Open RIA 662725 (IBSEN) and by the Ministerio de Economía y Competitividad (Spain) under grant FIS2015-64349-P (VARIANCE)

Fine mapping of the 9q31 Hirschsprung’s disease locus

Hirschsprung’s disease (HSCR) is a congenital disorder characterised by the absence of ganglia along variable lengths of the intestine. The RET gene is the major HSCR gene. Reduced penetrance of RET mutations and phenotypic variability suggest the involvement of additional modifying genes in the disease. A RET-dependent modifier locus was mapped to 9q31 in families bearing no coding sequence (CDS) RET mutations. Yet, the 9q31 causative locus is to be identified. To fine-map the 9q31 region, we genotyped 301 tag-SNPs spanning 7 Mb on 137 HSCR Dutch trios. This revealed two HSCR-associated regions that were further investigated in 173 Chinese HSCR patients and 436 controls using the genotype data obtained from a genome-wide association study recently conducted. Within one of the two identified regions SVEP1 SNPs were found associated with Dutch HSCR patients in the absence of RET mutations. This ratifies the reported linkage to the 9q31 region in HSCR families with no RET CDS mutations. However, this finding could not be replicated. In Chinese, HSCR was found associated with IKBKAP. In contrast, this association was stronger in patients carrying RET CDS mutations with p = 5.10 × 10−6 [OR = 3.32 (1.99, 5.59)] after replication. The HSCR-association found for IKBKAP in Chinese suggests population specificity and implies that RET mutation carriers may have an additional risk. Our finding is supported by the role of IKBKAP in the development of the nervous system

Phenomenology of a light gluon resonance in top-physics at Tevatron and LHC

We present a phenomenological analysis of the recent Tevatron results on the $t \bar t$ forward-backward asymmetry and invariant-mass spectrum assuming a new contribution from an s-channel gluon resonance with a mass in the range from 700 to 2500 GeV. In contrast to most of the previous works, this analysis shows that for masses below ~1 TeV resonant New Physics could accommodate the experimental data. In general, we find that axial-like couplings are preferred for light and top quark couplings, and that only top quark couples strongly to New Physics. We find that composite model scenarios arise naturally from only phenomenological analyses of the experimental results. We show that our results are compatible with recent LHC limits in dijet and $t \bar t$ production, and find some tension for large resonance mass ~2.5 TeV. We indicate as best observables for discriminating a relatively light new gluon a better resolution in CDF forward-backward asymmetry, as well as the $t \bar t$ charge asymmetry and invariant-mass spectrum at the LHC.Comment: 22 pages with 5 figure

Wheat-barley hybridization – the last forty years

Abstract Several useful alien gene transfers have been reported from related species into wheat (Triticum aestivum), but very few publications have dealt with the development of wheat/barley (Hordeum vulgare) introgression lines. An overview is given here of wheat 9 barley hybridization over the last forty years, including the development of wheat 9 barley hybrids, and of addition and translocation lines with various barley cultivars. A short summary is also given of the wheat 9 barley hybrids produced with other Hordeum species. The meiotic pairing behaviour of wheat 9 barley hybrids is presented, with special regard to the detection of wheat– barley homoeologous pairing using the molecular cytogenetic technique GISH. The effect of in vitro multiplication on the genome composition of intergeneric hybrids is discussed, and the production and characterization of the latest wheat/barley translocation lines are presented. An overview of the agronomical traits (b-glucan content, earliness, salt tolerance, sprouting resistance, etc.) of the newly developed introgression lines is given. The exploitation and possible use of wheat/barley introgression lines for the most up-to-date molecular genetic studies (transcriptome analysis, sequencing of flow-sorted chromosomes) are also discussed

Changes in individual and contextual socio-economic level influence on reproductive behavior in Spanish women in the MCC-Spain study

Background The association between socioeconomic level and reproductive factors has been widely studied. For example, it is well known that women with lower socioeconomic status (SES) tend to have more children, the age at first-born being earlier. However, less is known about to what extent the great socioeconomic changes occurred in a country (Spain) could modify women reproductive factors. The main purpose of this article is to analyze the influence of individual and contextual socioeconomic levels on reproductive factors in Spanish women, and to explore whether this influence has changed over the last decades. Methods We performed a cross-sectional design using data from 2038 women recruited as population-based controls in an MCC-Spain case-control study. Results Higher parent’s economic level, education level, occupational level and lower urban vulnerability were associated with higher age at first delivery and lower number of pregnancies. These associations were stronger for women born after 1950: women with unfinished primary education had their first delivery 6 years before women with high education if they were born after 1950 (23.4 vs. 29.8 years) but only 3 years before if they were born before 1950 (25.7 vs. 28.0 years). For women born after 1950, the number of pregnancies dropped from 2.1 (unfinished primary school) to 1.7 (high education), whereas it remained almost unchanged in women born before 1950. Conclusions Reproductive behavior was associated with both individual and area-level socio-economic indicators. Such association was stronger for women born after 1950 regarding age at first delivery and number of pregnancies and for women born before 1950 regarding consumption of hormonal contraceptives or postmenopausal therapy

Competing Neural Responses for Auditory and Visual Decisions

Why is it hard to divide attention between dissimilar activities, such as reading and listening to a conversation? We used functional magnetic resonance imaging (fMRI) to study interference between simple auditory and visual decisions, independently of motor competition. Overlapping activity for auditory and visual tasks performed in isolation was found in lateral prefrontal regions, middle temporal cortex and parietal cortex. When the visual stimulus occurred during the processing of the tone, its activation in prefrontal and middle temporal cortex was suppressed. Additionally, reduced activity was seen in modality-specific visual cortex. These results paralleled impaired awareness of the visual event. Even without competing motor responses, a simple auditory decision interferes with visual processing on different neural levels, including prefrontal cortex, middle temporal cortex and visual regions

Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of IL-8 in response to TLR-9 stimulation

Myeloid and plasmacytoid dendritic cells (mDCs, pDC) are crucial to the immune system, detecting microorganisms and linking the innate and adaptive immunity. pDC are present in small quantities in tissues that are in contact with the external environment; mainly the skin, the inner lining of the nose, lungs, stomach and intestines. They produce large amounts of IFN-α after stimulation and are pivotal for the induction of antiviral responses. Chronic obstructive pulmonary disease (COPD) patients are known to be more susceptible to viral infections. We have demonstrated that exposure of mDC to cigarette smoke extract (CSE) leads to the release of chemokines, however, not much is known about the role of pDC in COPD. In this study, we addressed several key questions with respect to the mechanism of action of CSE on human pDC in an in vitro model. Human pDCs were isolated from normal healthy volunteers and subjected to fresh CSE and the levels of IL-8, TNF-α, IP-10, IL-6, IL-1, IL-12 and IL-10 and IFN-α were studied by both ELISA and real time PCR methods. We observed that CSE augmented the production of IL-8 and suppressed the release of TNF-α, IL-6 and IFN-α. Moreover, CSE suppressed PI3K/Akt signalling in pDC. In conclusion, our data indicate that CSE has both the potential to diminish anti-viral immunity by downregulating the release of IFN-α and other pro-inflammatory cytokines while, at the same time, augmenting the pathogenesis of COPD via an IL-8 induced recruitment of neutrophils