Functional specialization within rostral prefrontal cortex (Area 10): a meta-analysis

One of the least well understood regions of the human brain is rostral prefrontal cortex, approximating Brodmann's area 10. Here, we investigate the possibility that there are functional subdivisions within this region by conducting a meta-analysis of 104 functional neuroimaging studies (using positron emission tomography/functional magnetic resonance imaging). Studies involving working memory and episodic memory retrieval were disproportionately associated with lateral activations, whereas studies involving mentalizing (i.e., attending to one's own emotions and mental states or those of other agents) were disproportionately associated with medial activations. Functional variation was also observed along a rostral-caudal axis, with studies involving mentalizing yielding relatively caudal activations and studies involving multiple-task coordination yielding relatively rostral activations. A classification algorithm was trained to predict the task, given the coordinates of each activation peak. Performance was well above chance levels (74% for the three most common tasks; 45% across all eight tasks investigated) and generalized to data not included in the training set. These results point to considerable functional segregation within rostral prefrontal cortex

Europe as a multilevel federation

Peer reviewedPublisher PD

Equilibration processes in the Warm-Hot Intergalactic Medium

The Warm-Hot Intergalactic Medium (WHIM) is thought to contribute about 40-50 % to the baryonic budget at the present evolution stage of the universe. The observed large scale structure is likely to be due to gravitational growth of density fluctuations in the post-inflation era. The evolving cosmic web is governed by non-linear gravitational growth of the initially weak density fluctuations in the dark energy dominated cosmology. Non-linear structure formation, accretion and merging processes, star forming and AGN activity produce gas shocks in the WHIM. Shock waves are converting a fraction of the gravitation power to thermal and non-thermal emission of baryonic/leptonic matter. They provide the most likely way to power the luminous matter in the WHIM. The plasma shocks in the WHIM are expected to be collisionless. Collisionless shocks produce a highly non-equilibrium state with anisotropic temperatures and a large differences in ion and electron temperatures. We discuss the ion and electron heating by the collisionless shocks and then review the plasma processes responsible for the Coulomb equilibration and collisional ionisation equilibrium of oxygen ions in the WHIM. MHD-turbulence produced by the strong collisionless shocks could provide a sizeable non-thermal contribution to the observed Doppler parameter of the UV line spectra of the WHIM.Comment: 13 pages, 4 figures, accepted for publication in Space Science Reviews, special issue "Clusters of galaxies: beyond the thermal view", Editor J.S. Kaastra, Chapter 8; work done by an international team at the International Space Science Institute (ISSI), Bern, organised by J.S. Kaastra, A.M. Bykov, S. Schindler & J.A.M. Bleeke

Modeling of Photoionized Plasmas

In this paper I review the motivation and current status of modeling of plasmas exposed to strong radiation fields, as it applies to the study of cosmic X-ray sources. This includes some of the astrophysical issues which can be addressed, the ingredients for the models, the current computational tools, the limitations imposed by currently available atomic data, and the validity of some of the standard assumptions. I will also discuss ideas for the future: challenges associated with future missions, opportunities presented by improved computers, and goals for atomic data collection.Comment: 17 pages, 8 figures, to appear in the proceedings of Xray2010, Utrecht, the Netherlands, March 15-17 201

SD-brane gravity fields and rolling tachyons

S(pacelike)D-branes are objects arising naturally in string theory when Dirichlet boundary conditions are imposed on the time direction. SD-brane physics is inherently time-dependent. Previous investigations of gravity fields of SD-branes have yielded undesirable naked spacelike singularities. We set up the problem of coupling the most relevant open-string tachyonic mode to massless closed-string modes in the bulk, with backreaction and Ramond-Ramond fields included. We find solutions numerically in a self-consistent approximation; our solutions are naturally asymptotically flat and time-reversal asymmetric. We find completely nonsingular evolution; in particular, the dilaton and curvature are well-behaved for all time. The essential mechanism for spacetime singularity resolution is the inclusion of full backreaction between the bulk fields and the rolling tachyon. Our analysis is not the final word on the story, because we have to make some significant approximations, most notably homogeneity of the tachyon on the unstable branes. Nonetheless, we provide significant progress in plugging a gaping hole in prior understanding of the gravity fields of SD-branes.Comment: References added. Analysis for much broader range of solutions presented. Conclusions unchanged. Time-reversal symmetric examples ruled out, new examples are provide

Gauge invariant derivative expansion of the effective action at finite temperature and density and the scalar field in 2+1 dimensions

A method is presented for the computation of the one-loop effective action at finite temperature and density. The method is based on an expansion in the number of spatial covariant derivatives. It applies to general background field configurations with arbitrary internal symmetry group and space-time dependence. Full invariance under small and large gauge transformations is preserved without assuming stationary or Abelian fields nor fixing the gauge. The method is applied to the computation of the effective action of spin zero particles in 2+1 dimensions at finite temperature and density and in presence of background gauge fields. The calculation is carried out through second order in the number of spatial covariant derivatives. Some limiting cases are worked out.Comment: 34 pages, REVTEX, no figures. Further comments adde

Surface Terms as Counterterms in the AdS/CFT Correspondence

We examine the recently proposed technique of adding boundary counterterms to the gravitational action for spacetimes which are locally asymptotic to anti-de Sitter. In particular, we explicitly identify higher order counterterms, which allow us to consider spacetimes of dimensions d<=7. As the counterterms eliminate the need of ``background subtraction'' in calculating the action, we apply this technique to study examples where the appropriate background was ambiguous or unknown: topological black holes, Taub-NUT-AdS and Taub-Bolt-AdS. We also identify certain cases where the covariant counterterms fail to render the action finite, and we comment on the dual field theory interpretation of this result. In some examples, the case of vanishing cosmological constant may be recovered in a limit, which allows us to check results and resolve ambiguities in certain asymptotically flat spacetime computations in the literature.Comment: Revtex, 18 pages. References updated and few typo's fixed. Final versio

Academic freedom: in justification of a universal ideal

This paper examines the justification for, and benefits of, academic freedom to academics, students, universities and the world at large. The paper surveys the development of the concept of academic freedom within Europe, more especially the impact of the reforms at the University of Berlin instigated by Wilhelm von Humboldt. Following from this, the paper examines the reasons why the various facets of academic freedom are important and why the principle should continue to be supported

Supporting the Construction of Workflows for Biodiversity Problem-Solving Accessing Secure, Distributed Resources

In the Biodiversity World (BDW) project we have created a flexible and extensible Web Services-based Grid environment for biodiversity researchers to solve problems in biodiversity and analyse biodiversity patterns. In this environment, heterogeneous and globally distributed biodiversity-related resources such as data sets and analytical tools are made available to be accessed and assembled by users into workflows to perform complex scientific experiments. One such experiment is bioclimatic modelling of the geographical distribution of individual species using climate variables in order to explain past and future climate-related changes in species distribution. Data sources and analytical tools required for such analysis of species distribution are widely dispersed, available on heterogeneous platforms, present data in different formats and lack inherent interoperability. The present BDW system brings all these disparate units together so that the user can combine tools with little thought as to their original availability, data formats and interoperability. The new prototype BDW system architecture not only brings together heterogeneous resources but also enables utilisation of computational resources and provides a secure access to BDW resources via a federated security model. We describe features of the new BDW system and its security model which enable user authentication from a workflow application as part of workflow execution