Genome-wide scan using DArT markers for selection footprints in six-rowed naked barley from the Tibetan Plateau

As one of the world’s earliest domesticated crops, barley is a model species for the study of evolution and domestication. Domestication is an evolutionary process whereby a population adapts, through selection; to new environments created by human cultivation. We describe the genome-scanning of molecular diversity to assess the evolution of barley in the Tibetan Plateau. We used 667 Diversity Arrays Technology (DArT) markers to genotype 185 barley landraces and wild barley accessions from the Tibetan Plateau. Genetic diversity in wild barley was greater than in landraces at both genome and chromosome levels, except for chromosome 3H. Landraces and wild barley accessions were clearly differentiated genetically, but a limited degree of introgression was still evident. Significant differences in diversity between barley subspecies at the chromosome level were observed for genes known to be related to physiological and phenotypical traits, disease resistance, abiotic stress tolerance, malting quality and agronomic traits. Selection on the genome of six-rowed naked barley has shown clear multiple targets related to both its specific end-use and the extreme environment in Tibet. Our data provide a platform to identify the genes and genetic mechanisms that underlie phenotypic changes, and provide lists of candidate domestication genes for modified breeding strategies

Interacting Agegraphic Dark Energy

A new dark energy model, named "agegraphic dark energy", has been proposed recently, based on the so-called K\'{a}rolyh\'{a}zy uncertainty relation, which arises from quantum mechanics together with general relativity. In this note, we extend the original agegraphic dark energy model by including the interaction between agegraphic dark energy and pressureless (dark) matter. In the interacting agegraphic dark energy model, there are many interesting features different from the original agegraphic dark energy model and holographic dark energy model. The similarity and difference between agegraphic dark energy and holographic dark energy are also discussed.Comment: 10 pages, 5 figures, revtex4; v2: references added; v3: accepted by Eur. Phys. J. C; v4: published versio

Chameleonic Generalized Brans--Dicke model and late-time acceleration

In this paper we consider Chameleonic Generalized Brans--Dicke Cosmology in the framework of FRW universes. The bouncing solution and phantom crossing is investigated for the model. Two independent cosmological tests: Cosmological Redshift Drift (CRD) and distance modulus are applied to test the model with the observation.Comment: 20 pages, 15 figures, to be published in Astrophys. Space Sci. (2011

Running coupling: Does the coupling between dark energy and dark matter change sign during the cosmological evolution?

In this paper we put forward a running coupling scenario for describing the interaction between dark energy and dark matter. The dark sector interaction in our scenario is free of the assumption that the interaction term $Q$ is proportional to the Hubble expansion rate and the energy densities of dark sectors. We only use a time-variable coupling $b(a)$ (with $a$ the scale factor of the universe) to characterize the interaction $Q$. We propose a parametrization form for the running coupling $b(a)=b_0a+b_e(1-a)$ in which the early-time coupling is given by a constant $b_e$, while today the coupling is given by another constant, $b_0$. For investigating the feature of the running coupling, we employ three dark energy models, namely, the cosmological constant model ($w=-1$), the constant $w$ model ($w=w_0$), and the time-dependent $w$ model ($w(a)=w_0+w_1(1-a)$). We constrain the models with the current observational data, including the type Ia supernova, the baryon acoustic oscillation, the cosmic microwave background, the Hubble expansion rate, and the X-ray gas mass fraction data. The fitting results indicate that a time-varying vacuum scenario is favored, in which the coupling $b(z)$ crosses the noninteracting line ($b=0$) during the cosmological evolution and the sign changes from negative to positive. The crossing of the noninteracting line happens at around $z=0.2-0.3$, and the crossing behavior is favored at about 1$\sigma$ confidence level. Our work implies that we should pay more attention to the time-varying vacuum model and seriously consider the phenomenological construction of a sign-changeable or oscillatory interaction between dark sectors.Comment: 8 pages, 5 figures; refs added; to appear in EPJ

Dark Energy and Neutrino CPT Violation

In this paper we study the dynamical CPT violation in the neutrino sector induced by the dark energy of the Universe. Specifically we consider a dark energy model where the dark energy scalar derivatively interacts with the right-handed neutrinos. This type of derivative coupling leads to a cosmological CPT violation during the evolution of the background field of the dark energy. We calculate the induced CPT violation of left-handed neutrinos and find the CPT violation produced in this way is consistent with the present experimental limit and sensitive to the future neutrino oscillation experiments, such as the neutrino factory.Comment: 10 pages, 2 figures. Typos corrected and references added. To be published in EPJ

Non-minimal coupling of the phantom field and cosmic acceleration

Motivated by the recent interest in phantom fields as candidates for the dark energy component, we investigate the consequences of the phantom field when is minimally coupled to gravity. In particular, the necessary (but insufficient) conditions for the acceleration and superacceleration of the universe are obtained when the non-minimal coupling term is taken into account. Furthermore, the necessary condition for the cosmic acceleration is derived when the phantom field is non-minimally coupled to gravity and baryonic matter is included.Comment: 9 pages, no figures; (v2) title slightly changed, one reference and acknowledgments added, no change in physic

Generalized Second Law of Thermodynamics in f(T)f(T) Gravity with Entropy Corrections

We study the generalized second law (GSL) of thermodynamics in $f(T)$ cosmology. We consider the universe as a closed bounded system filled with $n$ component fluids in the thermal equilibrium with the cosmological boundary. We use two different cosmic horizons: the future event horizon and the apparent horizon. We show the conditions under which the GSL will be valid in specific scenarios of the quintessence and the phantom energy dominated eras. Further we associate two different entropies with the cosmological horizons: with a logarithmic correction term and a power-law correction term. We also find the conditions for the GSL to be satisfied or violated by imposing constraints on model parameters.Comment: 17 pages, no figure, title changed, version accepted for publication in Astrophysics and Space Scienc

Comprehensive analysis of epigenetic clocks reveals associations between disproportionate biological ageing and hippocampal volume

The concept of age acceleration, the difference between biological age and chronological age, is of growing interest, particularly with respect to age-related disorders, such as Alzheimer’s Disease (AD). Whilst studies have reported associations with AD risk and related phenotypes, there remains a lack of consensus on these associations. Here we aimed to comprehensively investigate the relationship between five recognised measures of age acceleration, based on DNA methylation patterns (DNAm age), and cross-sectional and longitudinal cognition and AD-related neuroimaging phenotypes (volumetric MRI and Amyloid-β PET) in the Australian Imaging, Biomarkers and Lifestyle (AIBL) and the Alzheimer’s Disease Neuroimaging Initiative (ADNI). Significant associations were observed between age acceleration using the Hannum epigenetic clock and cross-sectional hippocampal volume in AIBL and replicated in ADNI. In AIBL, several other findings were observed cross-sectionally, including a significant association between hippocampal volume and the Hannum and Phenoage epigenetic clocks. Further, significant associations were also observed between hippocampal volume and the Zhang and Phenoage epigenetic clocks within Amyloid-β positive individuals. However, these were not validated within the ADNI cohort. No associations between age acceleration and other Alzheimer’s disease-related phenotypes, including measures of cognition or brain Amyloid-β burden, were observed, and there was no association with longitudinal change in any phenotype. This study presents a link between age acceleration, as determined using DNA methylation, and hippocampal volume that was statistically significant across two highly characterised cohorts. The results presented in this study contribute to a growing literature that supports the role of epigenetic modifications in ageing and AD-related phenotypes