Focusing in Asynchronous Games

Game semantics provides an interactive point of view on proofs, which enables one to describe precisely their dynamical behavior during cut elimination, by considering formulas as games on which proofs induce strategies. We are specifically interested here in relating two such semantics of linear logic, of very different flavor, which both take in account concurrent features of the proofs: asynchronous games and concurrent games. Interestingly, we show that associating a concurrent strategy to an asynchronous strategy can be seen as a semantical counterpart of the focusing property of linear logic

Focalisation and Classical Realisability (version with appendices)

The original publication is avalaible at : www.springerlink.comInternational audienceWe develop a polarised variant of Curien and Herbelin's lambda-bar-mu-mu-tilde calculus suitable for sequent calculi that admit a focalising cut elimination (i.e. whose proofs are focalised when cut-free), such as Girard's classical logic LC or linear logic. This gives a setting in which Krivine's classical realisability extends naturally (in particular to call-by-value), with a presentation in terms of orthogonality. We give examples of applications to the theory of programming languages

The efficacy of adding short-term psychodynamic psychotherapy to antidepressants in the treatment of depression:A systematic review and meta-analysis of individual participant data

Contains fulltext : 220185.pdf (Publisher’s version ) (Closed access)Purpose: We examined the efficacy of adding short-term psychodynamic psychotherapy (STPP) to antidepressants in the treatment of depression by means of a systematic review and meta-analysis of individual participant data, which is currently considered the most reliable method for evidence synthesis. Results: A thorough systematic literature search resulted in 7 studies comparing combined treatment of antidepressants and STPP versus antidepressant mono-therapy (n = 3) or versus antidepressants and brief supportive psychotherapy (n = 4). Individual participant data were obtained for all these studies and totaled 482 participants. Across the total sample of studies, combined treatment of antidepressants and STPP was found significantly more efficacious in terms of depressive symptom levels at both post-treatment (Cohen's d = 0.26, SE = 0.10, p = .01) and follow-up (d = 0.50, SE = 0.10, p < .001). This effect was most apparent at follow-up and in studies examining STPP's specific treatment efficacy. Effects were still apparent in analyses that controlled for risk of bias and STPP quality in the primary studies. Conclusions: These findings support the evidence-base of adding STPP to antidepressants in the treatment of depression. However, further studies are needed, particularly assessing outcome measures other than depression and cost-effectiveness, as well as examining the relative merits of STPP versus other psychotherapies as added to antidepressants.10 p

Polarized Substructural Session Types

Abstract. The deep connection between session-typed concurrency and linear logic is embodied in the language SILL that integrates functional and message-passing concurrent programming. The exacting nature of linear typing provides strong guarantees, such as global progress, absence of deadlock, and race freedom, but it also requires explicit resource man-agement by the programmer. This burden is alleviated in an affine type system where resources need not be used, relying on a simple form of garbage collection. In this paper we show how to effectively support both linear and affine typing in a single language, in addition to the already present unre-stricted (intuitionistic) types. The approach, based on Benton’s adjoint construction, suggests that the usual distinction between synchronous and asynchronous communication can be viewed through the lens of modal logic. We show how polarizing the propositions into positive and negative connectives allows us to elegantly express synchronization in the type instead of encoding it by extra-logical means.

Impaired health-related quality of life in idiopathic inflammatory myopathies: a cross-sectional analysis from the COVAD-2 e-survey

Objectives To investigate health-related quality of life in patients with idiopathic inflammatory myopathies (IIMs) compared with those with non-IIM autoimmune rheumatic diseases (AIRDs), non-rheumatic autoimmune diseases (nrAIDs) and without autoimmune diseases (controls) using Patient-Reported Outcome Measurement Information System (PROMIS) instrument data obtained from the second COVID-19 vaccination in autoimmune disease (COVAD-2) e-survey database. Methods Demographics, diagnosis, comorbidities, disease activity, treatments and PROMIS instrument data were analysed. Primary outcomes were PROMIS Global Physical Health (GPH) and Global Mental Health (GMH) scores. Factors affecting GPH and GMH scores in IIMs were identified using multivariable regression analysis. Results We analysed responses from 1582 IIM, 4700 non-IIM AIRD and 545 nrAID patients and 3675 controls gathered through 23 May 2022. The median GPH scores were the lowest in IIM and non-IIM AIRD patients {13 [interquartile range (IQR) 10–15] IIMs vs 13 [11–15] non-IIM AIRDs vs 15 [13–17] nrAIDs vs 17 [15–18] controls, P < 0.001}. The median GMH scores in IIM patients were also significantly lower compared with those without autoimmune diseases [13 (IQR 10–15) IIMs vs 15 (13–17) controls, P < 0.001]. Inclusion body myositis, comorbidities, active disease and glucocorticoid use were the determinants of lower GPH scores, whereas overlap myositis, interstitial lung disease, depression, active disease, lower PROMIS Physical Function 10a and higher PROMIS Fatigue 4a scores were associated with lower GMH scores in IIM patients. Conclusion Both physical and mental health are significantly impaired in IIM patients, particularly in those with comorbidities and increased fatigue, emphasizing the importance of patient-reported experiences and optimized multidisciplinary care to enhance well-being in people with IIMs

LINK: a Proof Environment based on Proof nets

Colloque avec actes et comité de lecture. internationale.International audienceLINK is a proof environment including proof nets-based provers for multiplicative linear logics: mixed linear logic, or recently called non-commutative logic (MNL), commutative linear logic (MLL) and non-commutative (or cyclic) linear logic (MCyLL). Its main characteristic is the provability analysis through automatic proof nets construction that is a powerful alternative to deal with resource management in proof search. These provers can be also seen as implementations of new connection methods for these linear logic fragments