2,160 research outputs found
Preliminary analysis of development programs performance
The regional development programs promoted by the national governments and international multilateral agencies, like the World Bank and the Inter American Development Bank, are oriented to public policies under which public goods, like public services and infrastructures, are supplied to underdeveloped regions, many in Latin America. More a more evidences are pointing to the fact that success of these programs depends in a good part of externalities, which are related to the changes in the form of networking and values among the stakeholders in the territory. These externalities are defined as the Social Capita
AVALIAÇÃO NUTRITIVA DE FENOS DA PASTAGEM NATURAL DO PARANÁ
Fenos de pastagem natural do Paraná colhidos durante o verão nos municípios de Ponta
Grossa, Guarapuava e Tibagi, foram avaliados pela composição química, determinação dos
coeficientes de digestibilidade e consumo voluntário com ovinos. Baseados na composição química,
os valores encontrados foram semelhantes para os três fenos estudados. No entanto, o feno de
Guarapuava apresentou valores mais elevados em FDN e lignina. Entre os coeficientes de
digestibilidade, somente o da proteína bruta e do FDN não apresentaram diferença significativa entre
os locais (P>0,05). Para a digestibilidade da matéria seca e energia bruta, o feno de Ponta Grossa
mostrou-se superior ao de Tibagi. No consumo de matéria seca, proteína e energia digestíveis, não
houve diferença significativa (P>0,05) entre locais, mas em relação a energia líquida de manutenção
o feno de Ponta Grossa diferiu significativamente do feno de Tibagi (P0.05). As far as digestibility of the dry matter and gross energy are concerned,
the hay of Ponta Grossa showed superior qualities when compared with the Tibagi one. No significant
differences (P>0.05) were found between all the hays studied. However, in regard to liquid
maintenance energy, the Ponta Grossa hay differed significantly from the Tibagi hay (
Evaluación de modelos de crecimiento en difrerentes condiciones de cultivo de pejerrey (Odontesthes bonariensis)
Fil: Solimano, Patricio José. Universidad Nacional de Río Negro. Escuela de producción, tecnología y medio ambiente; ArgentinaFil: Garcia de Souza, Javier Ricardo. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Instituto de Limnología Dr. Raúl A. Ringuelet; ArgentinaFil: Maiztegui, Tomás. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Instituto de Limnología Dr. Raúl A. Ringuelet; ArgentinaFil: Bazzani, J.L.. Universidad Nacional de Río Negro. Escuela de producción, tecnología y medio ambiente; ArgentinaFil: Baigún, Claudio Rafael Mariano. Universidad Nacional de San Martín. Instituto Tecnológico de Chascomús. Instituto de Investigaciones Biotecnológicas; ArgentinaFil: Colautti, Darío César. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. Instituto de Limnología Dr. Raúl A. Ringuelet; Argentin
An architecture for message exchange in pervasive healthcare based on the use of intelligent agents
Aims: This paper proposes an architecture for the exchange of context-aware messages in Pervasive Healthcare environments.\ud
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Materials and methods: In Pervasive Healthcare, novel information and communication technologies are applied to support the provision of health services anywhere, at anytime, and to anyone. Ubiquitous Computing technologies allow efficient and safe information exchange amongst caregivers and their patients in communities, homes and hospitals. Since health systems may offer their health records in various electronic formats, the openEHR foundation has proposed a dual model to achieve semantic interoperability between such systems. Intelligent Agents is a technology that has been applied to simulate human skills in healthcare procedures. This architecture is based on technologies from Ubiquitous Computing and Intelligent Agents, and complies with the openEHR dual model.\ud
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Results: This architecture was demonstrated and evaluated in a controlled experiment that we conducted in the cardiology department of a hospital located in the city of Marília (São Paulo, Brazil).\ud
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Conclusion: An application was developed to evaluate this architecture, and the results showed that the architecture is suitable for facilitating the development of healthcare systems by offering generic resources and powerful solution to integrate these systems
ESTUDOS DE CARACTERÍSTICAS REPRODUTIVAS DE ANIMAIS DA RAÇA CANCHIM, CRIADOS A PASTO, NO ESTADO DO PARANÁ, BRASIL
Beef production efficiency depends heavely on reproductive performance. Information on age at first calving indicates sexual precocity. Good management of young animal and elimination of factors that negatively interfere with growth and development of heifers contribute to shorten age at first calving. This trait, together with calving interval and conception rate of heifers after their first calving were studied from records of 3.091 Canchim females, born from 1974 through 1998, at Estação Experimental Fazenda Modelo/IAPAR, Ponta Grossa-PR. Data were analyzed using SAS program. Average calving interval, computed using least squares methods, was 16.79 ± 0.43 months, with coefficient of variation equal to 32.07. The R square from the statistical model was 19.84%. For calving interval, only year of birth, month of birth and month of previous calving were significant. When interval between first and second calving was studied, month of previous calving was not significant. Considering that data came from controlled animals, the average calving interval was too long in contrast with the ideal (12 months). Improving management practices should result in shorter calving interval in this herd.A produção eficiente de gado de corte depende muito do seu desempenho reprodutivo. Informações sobre a idade ao primeiro parto evidenciam a precocidade do animal. A boa criação dos animais jovens e a eliminação de fatores que interferem negativamente no crescimento e desenvolvimento das novilhas contribuem para diminuir a idade ao primeiro parto. Essa característica, juntamente com o intervalo de partos e a taxa de reconcepção de novilhas Canchim foram estimadas analisando-se registros pertencentes ao banco de dados do Instituto Agronômico do Paraná (IAPAR), totalizando 3.091 partos, ocorridos no período de 1974 a 1998. Esses dados foram analisados utilizando o programa SAS, para se processar as respectivas análises estatísticas. A média para o intervalo de partos geral, estimada pelo método dos quadrados mínimos, foi de 16,79 ± 0,43 meses. O modelo estatístico justificou 19,84%, com um coeficiente de variação de 32,07. Das fontes de variação do modelo, apenas mês, ano e mês do parto anterior foram significativos para o intervalo de partos (geral). Quando se estudou essa característica entre o primeiro e segundo parto, o mês do parto anterior não foi significativo, apenas mês e ano de parto o foram. Considerando que os dados são provenientes de animais controlados, constatou-se médias elevadas em relação ao ideal (12 meses). A implementação de melhorias no manejo para esses animais pode reduzir os valores de intervalo entre partos na propriedade
Subtelomeric I-scei-mediated Double-strand Breaks Are Repaired By Homologous Recombination In Trypanosoma Cruzi
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Trypanosoma cruzi chromosome ends are enriched in surface protein genes and pseudogenes (e.g., trans-sialidases) surrounded by repetitive sequences. It has been proposed that the extensive sequence variability among members of these protein families could play a role in parasite infectivity and evasion of host immune response. In previous reports we showed evidence suggesting that sequences located in these regions are subjected to recombination. To support this hypothesis we introduced a double-strand break (DSB) at a specific target site in a T. cruzi subtelomeric region cloned into an artificial chromosome (pTAC). This construct was used to transfect T. cruzi epimastigotes expressing the I-SceI meganuclease. Examination of the repaired sequences showed that DNA repair occurred only through homologous recombination (HR) with endogenous subtelomeric sequences. Our findings suggest that DSBs in subtelomeric repetitive sequences followed by HR between them may contribute to increased variability in T. cruzi multigene families. © 2016 Chiurillo, Moraes Barros, Souza, Marini, Antonio, Cortez, Curto, Lorenzi, Schijman, Ramirez and da Silveira.7DEC11/51475-3, FAPESP, Fundação de Amparo à Pesquisa do Estado de São Paulo11/51693-0, FAPESP, Fundação de Amparo à Pesquisa do Estado de São Paulo306591/2015-4, CNPq, Conselho Nacional de Desenvolvimento Científico e TecnológicoFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq
Emissioin of Intermediate Mass Fragments During Fission
This research was sponsored by the National Science Foundation Grant NSF PHY-931478
Albedo and estimates of net radiation for green beans under polyethylene cover and field conditions
Estradiol and progesterone fecal metabolites analysis in crab-eating-fox (Cerdocyoun thous)
Using discrete Ricci curvatures to infer COVID-19 epidemic network fragility and systemic risk
The damage of the novel Coronavirus disease (COVID-19) is reaching unprecedented scales. There are numerous classical epidemiology models trying to quantify epidemiology metrics. Usually, to forecast epidemics, classical approaches need parameter estimations, such as the contagion rate or the basic reproduction number. Here, we propose a data-driven, parameter-free, geometric approach to access the emergence of a pandemic state by studying the Forman-Ricci and Ollivier- Ricci network curvatures. Discrete Ollivier-Ricci curvature has been used successfully to forecast risk in nancial networks and we suggest that those results can provide analogous results for COVID-19 epidemic time-series. We rst compute both curvatures in a toy-model of epidemic time-series with delays, which allows us to create epidemic networks. We also compared our results to classical network metrics. By doing so, we are able to verify that the Ollivier-Ricci and Forman-Ricci curvatures can be a parameter-free estimate for identifying a pandemic state in the simulated epidemic. On this basis, we then compute both Forman-Ricci and Ollivier-Ricci curvatures for real epidemic networks built from COVID-19 epidemic time-series available at the World Health Organization (WHO). This approach allow us to detect early warning signs of the emergence of the pandemic. The advantage of our method lies in providing an early geometrical data marker for the pandemic state, regardless of parameter estimation and stochastic modelling. This work opens the possibility of using discrete geometry to study epidemic networks.
Keywords: COVID-19, SARS2, Forman-Ricci Curvature, Ollivier-Ricci curvature, Epidemiology, Topologi- cal Data Analysi
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