Headache in Behçet’s disease: case reports and literature review

Objective: To evaluate the prevalence of headache and its different patterns in patients with Behçet’s disease (BD) with and without neurological involvement and to investigate clinical correlations. Methods: Patients fulfilling the International Study Group criteria for Behçet disease (ISGc) were studied. Patients were invited to fill a “headache questionnaire”, which consisted of two sections: the first one included demographic and anamnestic data, family history for both headache and BD, disease duration and clinical manifestations of BD; the second section included items about headache, investigated accordingly to International Headache Society diagnostic criteria (IHS, 2004). Clinical history and current comorbidities-medications were collected. Each patient underwent a neurological examination to assess neurological involvement (Neuro-BD) and, if necessary, instrumental investigations. One hundred-fifty healthy subjects matched for age and gender were used as control group for comparison. Results: Of the 55 patients diagnosed as BD (ISG criteria) 41 patients adhered and were enrolled into the study. Headache occurred in 29 of BD patients (70,7%) and in 13 of Neuro-BD patients (92,8%). Migraine without aura did prove the most frequent type of headache in BD patients (with and without neurological involvement) and there were no differences in the frequency of the different pattern of headache between BD patients and controls. Conclusions: Headache is a frequent manifestation in BD and primary headache like migraine emerged as the most frequent type of headache. A careful search for headache should be included in the diagnostic work-up of BD since this manifestation may be related to the underlying disease

Superstripes and complexity in high-temperature superconductors

While for many years the lattice, electronic and magnetic complexity of high-temperature superconductors (HTS) has been considered responsible for hindering the search of the mechanism of HTS now the complexity of HTS is proposed to be essential for the quantum mechanism raising the superconducting critical temperature. The complexity is shown by the lattice heterogeneous architecture: a) heterostructures at atomic limit; b) electronic heterogeneity: multiple components in the normal phase; c) superconducting heterogeneity: multiple superconducting gaps in different points of the real space and of the momentum space. The complex phase separation forms an unconventional granular superconductor in a landscape of nanoscale superconducting striped droplets which is called the "superstripes" scenario. The interplay and competition between magnetic orbital charge and lattice fluctuations seems to be essential for the quantum mechanism that suppresses thermal decoherence effects at an optimum inhomogeneity.Comment: 20 pages, 3 figures; J. Supercon. Nov. Mag. 201

Reversible posterior leucoencephalopathy syndrome (RPLS) related to hypertension: case report

none5---noneCesnik E.; Casetta I.; Capone JG.; Granieri E.; Tola MRCesnik, E.; Casetta, Ilaria; Capone, J. G.; Granieri, Enrico Gavino Giuseppe; Tola, M

Headache in Behçet’s disease: case reports and literature review

Objective: To evaluate the prevalence of headache and its different patterns in patients with Behçet’s disease (BD) with and without neurological involvement and to investigate clinical correlations. Methods: Patients fulfilling the International Study Group criteria for Behçet disease (ISGc) were studied. Patients were invited to fill a “headache questionnaire”, which consisted of two sections: the first one included demographic and anamnestic data, family history for both headache and BD, disease duration and clinical manifestations of BD; the second section included items about headache, investigated accordingly to International Headache Society diagnostic criteria (IHS, 2004). Clinical history and current comorbidities-medications were collected. Each patient underwent a neurological examination to assess neurological involvement (Neuro-BD) and, if necessary, instrumental investigations. One hundred-fifty healthy subjects matched for age and gender were used as control group for comparison. Results: Of the 55 patients diagnosed as BD (ISG criteria) 41 patients adhered and were enrolled into the study. Headache occurred in 29 of BD patients (70,7%) and in 13 of Neuro-BD patients (92,8%). Migraine without aura did prove the most frequent type of headache in BD patients (with and without neurological involvement) and there were no differences in the frequency of the different pattern of headache between BD patients and controls. Conclusions: Headache is a frequent manifestation in BD and primary headache like migraine emerged as the most frequent type of headache. A careful search for headache should be included in the diagnostic work-up of BD since this manifestation may be related to the underlying disease

Monitoraggio neurofisiologico della risposta terapeutica in pazienti con polineuropatia infiammatoria cronica demielinizzante

none8noneA. Lupato; L. Caniatti; E. Della Coletta; E. Gastaldo; E. Sette; J.G. Capone; V. Tugnoli; R. QuatraleLupato, Angelica; Caniatti, Luisa; DELLA COLETTA, Elena; Gastaldo, Ernesto; Sette, Elisabetta; Capone, JAY GUIDO; Tugnoli, Valeria; Quatrale, Rocc

Explosive-aggressive behavior related to bilateral subthalamic stimulation

We describe a patient with Parkinson's Disease who underwent bilateral subthalamic nucleus deep brain stimulation and later presented with episodes of aggressive behavior disorder with disturbed impulse control and an inability to control anger likely related to the deep brain stimulation 'switch-on stimulation'. We hypothesize that increasing voltage intensity could influence neighboring passing fibers coming from basal limbic system that are involved in the regulation of affect and emotional behavior. We suggest investigating these neuropsychological disturbances considering their influence on quality of life after surgery. © 2004 Elsevier Ltd. All rights reserved

Deep brain stimulation of the ventralis oralis anterior thalamic nucleus is effective for dystonic tremor.

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Spatial autocorrelation or model misspecification? The help from RESET and the curse of small samples

In regression analysis, model misspecification can produce spurious spatial correlation in the residuals. By means of Monte Carlo simulations, I show that the RESET test can help to disentangle this conundrum in large samples. Small samples can pose a serious challenge to finding the correct model