Robustness analysis of signaling transduction networks based on Monte-Carlo method

The dynamic behaviors of cell system were deep ly affected by structural complexity of cell signal transduction networks and uncertainty of kinetics parameters. How to quantitatively determinate the relation between system behaviors and parameters variations was an important p roblem of systems biology. In order to study robustness of NF - κB signal transduction networks, the parameters of system model were assigned to subject to stochastic distributions. Then, robustness of system output signal NF - κBn with respect to 64 parameters variations and amp litude variation of step input signal IKK was studied by means of Monte - Carlo method. The simulation results demonstrate that the oscillation behavior of system output signal NF - κBn is closely relative to 6 key rate constantswhose robustness isweak, and the amp litude variation of step input signal IKKmakes a great impact on the oscillation behavior of system output

Dark matter annihilation and non-thermal Sunyaev-Zel'dovich effect: II. dwarf spheroidal galaxy

We calculate the CMB temperature distortion due to the energetic electrons and positrons produced by dark matter annihilation (Sunyaev-Zel'dovich effect), in dwarf spheroidal galaxies (dSphs). In the calculation we have included two important effects which were previously ignored. First we show that the electron-positron pairs with energy less than GeV, which were neglected in previous calculation, could contribute a significant fraction of the total signal. Secondly we also consider the full effects of diffusion loss, which could significantly reduce the density of electron-positron pairs at the center of cuspy halos. For neutralinos, we confirm that detecting such kind of SZ effect is beyond the capability of the current or even the next generation experiments. In the case of light dark matter (LDM) the signal is much larger, but even in this case it is only marginally detectable with the next generation of experiment such as ALMA. We conclude that similar to the case of galaxy clusters, in the dwarf galaxies the SZ_2DM} effect is not a strong probe of DM annihilations.Comment: 22 pages, 9 figures, version accepted by JCA

On the Sunyaev-Zel'dovich effect from dark matter annihilation or decay in galaxy clusters

We revisit the prospects for detecting the Sunyaev Zel'dovich (SZ) effect induced by dark matter (DM) annihilation or decay. We show that with standard (or even extreme) assumptions for DM properties, the optical depth associated with relativistic electrons injected from DM annihilation or decay is much smaller than that associated with thermal electrons, when averaged over the angular resolution of current and future experiments. For example, we find: $\tau_{\rm DM} \sim 10^{-9}-10^{-5}$ (depending on the assumptions) for \mchi = 1 GeV and a density profile $\rho\propto r^{-1}$ for a template cluster located at 50 Mpc and observed within an angular resolution of $10"$, compared to $\tau_{\rm th}\sim 10^{-3}-10^{-2}$. This, together with a full spectral analysis, enables us to demonstrate that, for a template cluster with generic properties, the SZ effect due to DM annihilation or decay is far below the sensitivity of the Planck satellite. This is at variance with previous claims regarding heavier annihilating DM particles. Should DM be made of lighter particles, the current constraints from 511 keV observations on the annihilation cross section or decay rate still prevent a detectable SZ effect. Finally, we show that spatial diffusion sets a core of a few kpc in the electron distribution, even for very cuspy DM profiles, such that improving the angular resolution of the instrument, e.g. with ALMA, does not necessarily improve the detection potential. We provide useful analytical formulae parameterized in terms of the DM mass, decay rate or annihilation cross section and DM halo features, that allow quick estimates of the SZ effect induced by any given candidate and any DM halo profile.Comment: 27 p, 6 figs, additional section on spatial diffusion effects. Accepted for publication in JCA

On a two variable class of Bernstein-Szego measures

The one variable Bernstein-Szego theory for orthogonal polynomials on the real line is extended to a class of two variable measures. The polynomials orthonormal in the total degree ordering and the lexicographical ordering are constructed and their recurrence coefficients discussed.Comment: minor change

Hard diffractive quarkonium hadroproduction at high energies

We present a study of heavy quarkonium production in hard diffractive process by the Pomeron exchange for Tevatron and LHC energies. The numerical results are computed using recent experimental determination of the diffractive parton density functions in Pomeron and are corrected by unitarity corrections through gap survival probability factor. We give predictions for single as well as central diffractive ratios. These processes are sensitive to the gluon content of the Pomeron at small Bjorken-x and may be particularly useful in studying the small-x physics. They may also be a good place to test the different available mechanisms for quarkonium production at hadron colliders.Comment: 7 pages, 3 figures, 1 table. Final version to be published in European Physical Journal

ATIC and PAMELA Results on Cosmic e^\pm Excesses and Neutrino Masses

Recently the ATIC and PAMELA collaborations released their results which show the abundant e^\pm excess in cosmic rays well above the background, but not for the \bar{p}. Their data if interpreted as the dark matter particles' annihilation imply that the new physics with the dark matter is closely related to the lepton sector. In this paper we study the possible connection of the new physics responsible for the cosmic e^\pm excesses to the neutrino mass generation. We consider a class of models and do the detailed numerical calculations. We find that these models can natually account for the ATIC and PAMELA e^\pm and \bar{p} data and at the same time generate the small neutrino masses.Comment: 7 pages, 5 figures. Published version with minor corrections and more reference

Resistive and magnetized accretion flows with convection

We considered the effects of convection on the radiatively inefficient accretion flows (RIAF) in the presence of resistivity and toroidal magnetic field. We discussed the effects of convection on transports of angular momentum and energy. We established two cases for the resistive and magnetized RIAFs with convection: assuming the convection parameter as a free parameter and using mixing-length theory to calculate convection parameter. A self-similar method was used to solve the integrated equations that govern the behavior of the presented model. The solutions showed that the accretion and rotational velocities decrease by adding the convection parameter, while the sound speed increases. Moreover, by using mixing-length theory to calculate convection parameter, we found that the convection can be important in RIAFs with magnetic field and resistivity.Comment: 7 pages, 3 figures, accepted by Ap&S

A global overview of developments of urban and rural household GHG footprints from 2005 to 2015

Industrial Ecolog

Low-Luminosity Accretion in Black Hole X-ray Binaries and Active Galactic Nuclei

At luminosities below a few percent of Eddington, accreting black holes switch to a hard spectral state which is very different from the soft blackbody-like spectral state that is found at higher luminosities. The hard state is well-described by a two-temperature, optically thin, geometrically thick, advection-dominated accretion flow (ADAF) in which the ions are extremely hot (up to $10^{12}$ K near the black hole), the electrons are also hot ($\sim10^{9-10.5}$ K), and thermal Comptonization dominates the X-ray emission. The radiative efficiency of an ADAF decreases rapidly with decreasing mass accretion rate, becoming extremely low when a source reaches quiescence. ADAFs are expected to have strong outflows, which may explain why relativistic jets are often inferred from the radio emission of these sources. It has been suggested that most of the X-ray emission also comes from a jet, but this is less well established.Comment: To appear in "From X-ray Binaries to Quasars: Black Hole Accretion on All Mass Scales" edited by T. Maccarone, R. Fender, L. Ho, to be published as a special edition of "Astrophysics and Space Science" by Kluwe