708 research outputs found

    Safer recruitment practice: audit of exisiting recruitment practices in residential child care

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    In the wake of a number of high profile cases of the abuse of children and young people in residential child care, there have been repeated calls for the improvement of recruitment and selection of residential child care staff. Following the Children’s Safeguards Review the Scottish Executive funded the Scottish Recruitment and Selection Consortium to contribute to the safefguards for children by developing a toolkit for safer selection of staff. The toolkit was published in 2001. In 2004 the Scottish executive commisioned research form Residential Child Care (SIRCC) to identify current recruitment practices in residentialchild care for staff who have unsupervised contact with children and young people and to gauge opinion on how safer recruitment should be taken forward . A postal survey of operational and human resource managers responsible for the recruitment of residential childcare staff in local authority and voluntary organisationswas undertaken between January and April 2005. A sample of those respondents was invited to participate in semi-structured exploratory interviews, focusing in more detail on current practice and participants’ views on the implementation of the recommendations of the Toolkit

    El Acaparamiento de Tierras en América Latina y el Caribe Visto Desde una Perspectiva Internacional más Amplia

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    Introducción y mensajes claves Este documento se basa en la investigación empírica que fue encomendada por la Organización de las Naciones Unidas para la Alimentación y la Agricultura (FAO) sobre las condiciones y tendencias del ―acaparamiento de tierras‖ en 17 países de América Latina y el Caribe (véase el Anexo para una lista completa de los estudios, así como el documento síntesis correspondiente; FAO, 2011). Los 17 estudios se concluyeron a mediados de 2011. El marco analítico común de los estudios es amplio, pero a la vez focalizado. Por un lado es amplio porque analiza los procesos generales de las tierras rurales y la concentración de capital en el contexto de la globalización neoliberal. Por el otro, es focalizado porque analiza el fenómeno del ―acaparamiento de tierras‖ basándose estrictamente en tres dimensiones específicas, a saber: i) el gran alcance de las adquisiciones de tierra a gran escala; ii) la participación de los gobiernos extranjeros en estos tratos sobre tierras; y iii) el impacto negativo de dichas inversiones recientes en tierras sobre la seguridad alimentaria del país receptor. Es en gran medida debido a este tipo de marco analítico que la mayoría de los estudios pudieron desentrañar y recopilar gran cantidad de material empírico relacionado con la dinámica de las tierras en la región; sin embargo, dado que el enfoque de su análisis y conclusiones se basó en la definición y la dimensión angostas del acaparamiento de tierras, la conclusión obtenida fue que el ―acaparamiento de tierras‖ se da únicamente en dos países de la región: Argentina y Brasil. ..

    Climate change and beliefs in Cameroon: A qualitative study among farmers in the Equatorial and Sudano-Sahelian zones

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    The question of climate change is a topical issue as is shown by the numerous publications on the subject during the last few years. However few publications lay emphasis on populations considered to be particularly exposed to the problem of climate change (by location or by activity) and on the impact of religion on these beliefs.  In this study, two groups of Cameroon farmers working in two distinctive zones: equatorial and Sudano-Sahelian were interviewed about their social representation of climate change. Results with the free association method highlight two preoccupying social representations. The question of distance from the object is discussed in relation to studies carried out among wider publics. In addition, this study shows that religion can also play an important part in the construction of knowledge of climate change

    Additively manufactured heterogeneous substrates for three-dimensional control of local permittivity

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    The concept of using additive manufacturing as a method to construct heterogeneous substrates from a single building material via stereolithography is introduced. The dynamic variation of air cavities within the bulk material is used to control the effective permittivity of the host medium. The digitally driven layer process enables full three-dimensional variation of the local permittivity. The high resolution of stereolithography enables sub-millimetre control of air inclusion features. Measurements of the effective permittivity with different air fractions have been compared to analytical results

    Phylogenetic inferences of Atelinae (Platyrrhini) based on multi-directional chromosome painting in Brachyteles arachnoides, Ateles paniscus paniscus and Ateles b. marginatus

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    We performed multi-directional chromosome painting in a comparative cytogenetic study of the three Atelinae species Brachyteles arachnoides, Ateles paniscus paniscus and Ateles belzebuth marginatus, in order to reconstruct phylogenetic relationships within this Platyrrhini subfamily. Comparative chromosome maps between these species were established by multi-color fluorescence in situ hybridization ( FISH) employing human, Saguinus oedipus and Lagothrix lagothricha chromosome-specific probes. The three species included in this study and four previously analyzed species from all four Atelinae genera were subjected to a phylogenetic analysis on the basis of a data matrix comprised of 82 discrete chromosome characters. The results confirmed that Atelinae represent a monophyletic clade with a putative ancestral karyotype of 2n = 62 chromosomes. Phylogenetic analysis revealed an evolutionary branching sequence \{Alouatta \{Brachyteles \{Lagothrix and Ateles\}\}\} in Atelinae and \{Ateles belzebuth marginatus \{Ateles paniscus paniscus \{Ateles belzebuth hybridus and Ateles geoffroyi\}\}\} in genus Ateles. The chromosomal data support a re-evaluation of the taxonomic status of Ateles b. hybridus. Copyright (C) 2005 S. Karger AG, Basel

    Novel codon-optimized mini-intronic plasmid for efficient, inexpensive, and xeno-free induction of pluripotency

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    The development of human induced pluripotent stem cell (iPSC) technology has revolutionized the regenerative medicine field. This technology provides a powerful tool for disease modeling and drug screening approaches. To circumvent the risk of random integration into the host genome caused by retroviruses, non-integrating reprogramming methods have been developed. However, these techniques are relatively inefficient or expensive. The mini-intronic plasmid (MIP) is an alternative, robust transgene expression vector for reprogramming. Here we developed a single plasmid reprogramming system which carries codon-optimized (Co) sequences of the canonical reprogramming factors (Oct4, Klf4, Sox2, and c-Myc) and short hairpin RNA against p53 ("4-in-1 CoMiP"). We have derived human and mouse iPSC lines from fibroblasts by performing a single transfection. Either independently or together with an additional vector encoding for LIN28, NANOG, and GFP, we were also able to reprogram blood-derived peripheral blood mononuclear cells (PBMCs) into iPSCs. Taken together, the CoMiP system offers a new highly efficient, integration-free, easy to use, and inexpensive methodology for reprogramming. Furthermore, the CoMIP construct is color-labeled, free of any antibiotic selection cassettes, and independent of the requirement for expression of the Epstein-Barr Virus nuclear antigen (EBNA), making it particularly beneficial for future applications in regenerative medicine

    The risk of cardiac failure following metal-on-metal hip arthroplasty

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    Aims The aim of this study was to determine whether patients with metal-on-metal (MoM) arthroplasties of the hip have an increased risk of cardiac failure compared with those with alternative types of arthroplasties (non-MoM). Patients and Methods A linkage study between the National Joint Registry, Hospital Episodes Statistics and records of the Office for National Statistics on deaths was undertaken. Patients who underwent elective total hip arthroplasty between January 2003 and December 2014 with no past history of cardiac failure were included and stratified as having either a MoM (n = 53 529) or a nonMoM (n = 482 247) arthroplasty. The primary outcome measure was the time to an admission to hospital for cardiac failure or death. Analysis was carried out using data from all patients and from those matched by propensity score. Results The risk of cardiac failure was lower in the MoM cohort compared with the non-MoM cohort (adjusted hazard ratio (aHR) 0.901; 95% confidence interval (CI) 0.853 to 0.953). The risk of cardiac failure was similar following matching (aHR 0.909; 95% CI 0.838 to 0.987) and the findings were consistent in subgroup analysis. Conclusion The risk of cardiac failure following total hip arthroplasty was not increased in those in whom MoM implants were used, compared with those in whom other types of prostheses were used, in the first seven years after surgery. Cite this article: Bone Joint J 2018;100-B:20–

    Near-Surface Interface Detection for Coal Mining Applications Using Bispectral Features and GPR

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    The use of ground penetrating radar (GPR) for detecting the presence of near-surface interfaces is a scenario of special interest to the underground coal mining industry. The problem is difficult to solve in practice because the radar echo from the near-surface interface is often dominated by unwanted components such as antenna crosstalk and ringing, ground-bounce effects, clutter, and severe attenuation. These nuisance components are also highly sensitive to subtle variations in ground conditions, rendering the application of standard signal pre-processing techniques such as background subtraction largely ineffective in the unsupervised case. As a solution to this detection problem, we develop a novel pattern recognition-based algorithm which utilizes a neural network to classify features derived from the bispectrum of 1D early time radar data. The binary classifier is used to decide between two key cases, namely whether an interface is within, for example, 5 cm of the surface or not. This go/no-go detection capability is highly valuable for underground coal mining operations, such as longwall mining, where the need to leave a remnant coal section is essential for geological stability. The classifier was trained and tested using real GPR data with ground truth measurements. The real data was acquired from a testbed with coal-clay, coal-shale and shale-clay interfaces, which represents a test mine site. We show that, unlike traditional second order correlation based methods such as matched filtering which can fail even in known conditions, the new method reliably allows the detection of interfaces using GPR to be applied in the near-surface region. In this work, we are not addressing the problem of depth estimation, rather confining ourselves to detecting an interface within a particular depth range

    Closed Timelike Curves and Holography in Compact Plane Waves

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    We discuss plane wave backgrounds of string theory and their relation to Goedel-like universes. This involves a twisted compactification along the direction of propagation of the wave, which induces closed timelike curves. We show, however, that no such curves are geodesic. The particle geodesics and the preferred holographic screens we find are qualitatively different from those in the Goedel-like universes. Of the two types of preferred screen, only one is suited to dimensional reduction and/or T-duality, and this provides a ``holographic protection'' of chronology. The other type of screen, relevant to an observer localized in all directions, is constructed both for the compact and non-compact plane waves, a result of possible independent interest. We comment on the consistency of field theory in such spaces, in which there are closed timelike (and null) curves but no closed timelike (or null) geodesics.Comment: 21 pages, 3 figures, LaTe
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