460 research outputs found
Fermion-fermion scattering in the Gross-Neveu model: a status report
Encouraged by the successful applications of L\"uscher's method to boson--boson scattering we discuss the possibility of extracting scattering phase shifts from finite--volume energies for fermion--fermion scattering in the Gross--Neveu model
Monte Carlo simulation of SU(2) Yang-Mills theory with light gluinos
In a numerical Monte Carlo simulation of SU(2) Yang-Mills theory with light
dynamical gluinos the low energy features of the dynamics as confinement and
bound state mass spectrum are investigated. The motivation is supersymmetry at
vanishing gluino mass. The performance of the applied two-step multi-bosonic
dynamical fermion algorithm is discussed.Comment: latex, 48 pages, 16 figures with epsfi
Meson-meson scattering in the massive Schwinger model: a status report
We discuss the possibility of extracting phase shifts from finite volume energies for meson-meson scattering, where the mesons are fermion-antifermion bound states of the massive Schwinger model with SU(2) flavour symmetry. The existence of analytical strong coupling predictions for the mass spectrum and for the scattering phases makes it possible to test the reliability of numerical results
Numerical study of SU(2) Yang-Mills theory with gluinos
We report on a numerical investigation of the SU(2) gauge theory with
gluinos.
The low-lying spectrum in bosonic and fermionic channels is determined.
Improvements of the multi-bosonic algorithm are discussed.Comment: latex, 3 pages, 4 figures; Poster presented by K. Spanderen at
LATTICE9
Optimal MRI sequences for 68Ga-PSMA-11 PET/MRI in evaluation of biochemically recurrent prostate cancer.
BackgroundPET/MRI can be used for the detection of disease in biochemical recurrence (BCR) patients imaged with 68Ga-PSMA-11 PET. This study was designed to determine the optimal MRI sequences to localize positive findings on 68Ga-PSMA-11 PET of patients with BCR after definitive therapy. Fifty-five consecutive prostate cancer patients with BCR imaged with 68Ga-PSMA-11 3.0T PET/MRI were retrospectively analyzed. Mean PSA was 7.9 ± 12.9 ng/ml, and mean PSA doubling time was 7.1 ± 6.6 months. Detection rates of anatomic correlates for prostate-specific membrane antigen (PSMA)-positive foci were evaluated on small field of view (FOV) T2, T1 post-contrast, and diffusion-weighted images. For prostate bed recurrences, the detection rate of dynamic contrast-enhanced (DCE) imaging for PSMA-positive foci was evaluated. Finally, the detection sensitivity for PSMA-avid foci on 3- and 8-min PET acquisitions was compared.ResultsPSMA-positive foci were detected in 89.1% (49/55) of patients evaluated. Small FOV T2 performed best for lymph nodes and detected correlates for all PSMA-avid lymph nodes. DCE imaging performed the best for suspected prostate bed recurrence, detecting correlates for 87.5% (14/16) of PSMA-positive prostate bed foci. The 8-min PET acquisition performed better than the 3-min acquisition for lymph nodes smaller than 1 cm, detecting 100% (57/57) of lymph nodes less than 1 cm, compared to 78.9% (45/57) for the 3-min acquisition.ConclusionPSMA PET/MRI performed well for the detection of sites of suspected recurrent disease in patients with BCR. Of the MRI sequences obtained for localization, small FOV T2 images detected the greatest proportion of PSMA-positive abdominopelvic lymph nodes and DCE imaging detected the greatest proportion of PSMA-positive prostate bed foci. The 8-min PET acquisition was superior to the 3 min acquisition for detection of small lymph nodes
A rapid magnetic bead-based immunoassay for sensitive determination of diclofenac
Increasing contamination of environmental waters with pharmaceuticals represents an emerging threat for the drinking water quality and safety. In this regard, fast and reliable analytical methods are required to allow quick countermeasures in case of contamination. Here, we report the development of a magnetic bead-based immunoassay (MBBA) for the fast and cost-effective determination of the analgesic diclofenac (DCF) in water samples, based on diclofenac-coupled magnetic beads and a robust monoclonal anti-DCF antibody. A novel synthetic strategy for preparation of the beads resulted in an assay that enabled for the determination of diclofenac with a significantly lower limit of detection (400 ng/L) than the respective enzyme-linked immunosorbent assay (ELISA). With shorter incubation times and only one manual washing step required, the assay demands for remarkably shorter time to result (< 45 min) and less equipment than ELISA. Evaluation of assay precision and accuracy with a series of spiked water samples yielded results with low to moderate intra- and inter-assay variations and in good agreement with LC–MS/MS reference analysis. The assay principle can be transferred to other, e.g., microfluidic, formats, as well as applied to other analytes and may replace ELISA as the standard immunochemical method.
Graphical abstractBundesministerium für Bildung und Forschung
http://dx.doi.org/10.13039/501100002347Indo-German Science and Technology Centre
http://dx.doi.org/10.13039/501100018761Bundesanstalt für Materialforschung und -prüfung (BAM) (4232)Peer Reviewe
Numerical simulation of dynamical gluinos: experience with a multi-bosonic algorithm and first results
We report on our experience with the two-step multi-bosonic algorithm in a
large scale Monte Carlo simulation of the SU(2) Yang-Mills theory with
dynamical gluinos. First results are described on the low lying spectrum of
bound states, the string tension and the gluino condensate.Comment: LATTICE98(algorithms), latex using espcrc2.sty, 6 pages, 7 figure
О необходимости прослеживания Балейско-Дарасунского разлома в пределах Борщевочного кряжа
In this paper we present the development of a compact, thermo-optically stable and vibration and mechanical shock resistant mounting technique by soldering of optical components. Based on this technique a new generation of laser sources for aerospace applications is designed. In these laser systems solder technique replaces the glued and bolted connections between optical component, mount and base plate. Alignment precision in the arc second range and realization of long term stability of every single part in the laser system is the main challenge. At the Fraunhofer Institute for Laser Technology ILT a soldering and mounting technique has been developed for high precision packaging. The specified environmental boundary conditions (e.g. a temperature range of -40 °C to +50 °C) and the required degrees of freedom for the alignment of the components have been taken into account for this technique. In general the advantage of soldering compared to gluing is that there is no outgassing. In addition no flux is needed in our special process. The joining process allows multiple alignments by remelting the solder. The alignment is done in the liquid phase of the solder by a 6 axis manipulator with a step width in the nm range and a tilt in the arc second range. In a next step the optical components have to pass the environmental tests. The total misalignment of the component to its adapter after the thermal cycle tests is less than 10 arc seconds. The mechanical stability tests regarding shear, vibration and shock behavior are well within the requirements
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