3,061 research outputs found

    Locally continuously perfect groups of homeomorphisms

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    The notion of a locally continuously perfect group is introduced and studied. This notion generalizes locally smoothly perfect groups introduced by Haller and Teichmann. Next, we prove that the path connected identity component of the group of all homeomorphisms of a manifold is locally continuously perfect. The case of equivariant homeomorphism group and other examples are also considered.Comment: 14 page

    Spectroscopy using the Hadamard Transform V2

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    The IRMOS (infrared multiobject spectrometer) is an imaging dispersive spectrometer, with a micromirror array to select desired objects. In standard operation, the mirrors are "opened" in patterns such that the resulting spectra do not overlap on the detector. The IRMOS can also be operated in a Hadamard mode, in which the spectra are allowed to overlap, but are modulated by opening the mirrors in many combinations. This mode enables the entire field of view to be observed with the same sensitivity as in the standard mode if the uncertainty is dominated by the detector read noise. We explain the concept and discuss the benefits with an example observation of the Orion Trapezium using the 2.1 m telescope at Kitt Peak National Observatory

    The Expected Rate of Gamma-Ray Burst Afterglows In Supernova Searches

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    We predict the rate at which Gamma-Ray Burst (GRB) afterglows should be detected in supernova searches as a function of limiting flux. Although GRB afterglows are rarer than supernovae, they are detectable at greater distances because of their higher intrinsic luminosity. Assuming that GRBs trace the cosmic star formation history and that every GRB gives rise to a bright afterglow, we find that the average detection rate of supernovae and afterglows should be comparable at limiting magnitudes brighter than K=18. The actual rate of afterglows is expected to be somewhat lower since only a fraction of all gamma-ray selected GRBs were observed to have associated afterglows. However, the rate could also be higher if the initial gamma-ray emission from GRB sources is more beamed than their late afterglow emission. Hence, current and future supernova searches can place strong constraints on the afterglow appearance fraction and the initial beaming angle of GRB sources.Comment: 13 pages, submitted to ApJ

    The prevalences of Salmonella Genomic Island 1 variants in human and animal Salmonella Typhimurium DT104 are distinguishable using a Bayesian approach

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    Throughout the 1990s, there was an epidemic of multidrug resistant Salmonella Typhimurium DT104 in both animals and humans in Scotland. The use of antimicrobials in agriculture is often cited as a major source of antimicrobial resistance in pathogenic bacteria of humans, suggesting that DT104 in animals and humans should demonstrate similar prevalences of resistance determinants. Until very recently, only the application of molecular methods would allow such a comparison and our understanding has been hindered by the fact that surveillance data are primarily phenotypic in nature. Here, using large scale surveillance datasets and a novel Bayesian approach, we infer and compare the prevalence of Salmonella Genomic Island 1 (SGI1), SGI1 variants, and resistance determinants independent of SGI1 in animal and human DT104 isolates from such phenotypic data. We demonstrate differences in the prevalences of SGI1, SGI1-B, SGI1-C, absence of SGI1, and tetracycline resistance determinants independent of SGI1 between these human and animal populations, a finding that challenges established tenets that DT104 in domestic animals and humans are from the same well-mixed microbial population

    Geodesic distance for right invariant Sobolev metrics of fractional order on the diffeomorphism group

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    We study Sobolev-type metrics of fractional order s0s\geq0 on the group \Diff_c(M) of compactly supported diffeomorphisms of a manifold MM. We show that for the important special case M=S1M=S^1 the geodesic distance on \Diff_c(S^1) vanishes if and only if s12s\leq\frac12. For other manifolds we obtain a partial characterization: the geodesic distance on \Diff_c(M) vanishes for M=R×N,s<12M=\R\times N, s<\frac12 and for M=S1×N,s12M=S^1\times N, s\leq\frac12, with NN being a compact Riemannian manifold. On the other hand the geodesic distance on \Diff_c(M) is positive for dim(M)=1,s>12\dim(M)=1, s>\frac12 and dim(M)2,s1\dim(M)\geq2, s\geq1. For M=RnM=\R^n we discuss the geodesic equations for these metrics. For n=1n=1 we obtain some well known PDEs of hydrodynamics: Burgers' equation for s=0s=0, the modified Constantin-Lax-Majda equation for s=12s=\frac 12 and the Camassa-Holm equation for s=1s=1.Comment: 16 pages. Final versio

    Antimicrobial Resistance Profiles Diversity in Salmonella from Humans Cattle, 2004-2011

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    Analysis of long-term anti-microbial resistance (AMR) data is useful to understsource transmission dynamics of AMR. We analysed 5124 human clinical isolates from Washington State Department of Health, 391 cattle clinical isolates from the Washington Animal Disease Diagnostic Laboratory 1864 non-clinical isolates from foodborne disease research on dairies in the Pacific Northwest. Isolates were assigned profiles based on phenotypic resistance to 11 anti-microbials belonging to eight classes. Salmonella Typhimurium (ST), Salmonella Newport (SN) Salmonella Montevideo (SM) were the most common serovars in both humans cattle. Multinomial logistic regression showed ST SN from cattle had greater probability of resistance to multiple classes of anti-microbials than ST SN from humans (P < 0.0001). While these findings could be consistent with the belief that cattle are a source of resistant ST SN for people, occurrence of profiles unique to cattle not observed in temporally related human isolates indicates these profiles are circulating in cattle only. We used various measures to assess AMR diversity, conditional on the weighting of rare versus abundant profiles. AMR profile richness was greater in the common serovars from humans, although both source data sets were dominated by relatively few profiles. The greater profile richness in human Salmonella may be due to greater diversity of sources entering the human population compared to cattle or due to continuous evolution in the human environment. Also, AMR diversity was greater in clinical compared to non-clinical cattle Salmonella, this could be due to anti-microbial selection pressure in diseased cattle that received treatment. The use of bootstrapping techniques showed that although there were shared profiles between humans cattle, the expected observed number of profiles was different, suggesting Salmonella associated resistance from humans cattle may not be wholly derived from a common population

    Constraining magma storage conditions at a restless volcano in the Main Ethiopian Rift using phase equilibria models

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    This work is a contribution to the Natural Environment Research Council (NERC) funded RiftVolc project (NE/L013932/1, Rift volcanism: past, present, and future). W.H., T.A.M., and D.M.P. are supported by and contribute to the NERC Centre for the Observation and Modelling of Earthquakes, Volcanoes, and Tectonics (COMET). W.H. M.J.S. were supported by a NERC studentships NE/J5000045/1 and NE/K500811/01 respectively.The Main Ethiopian Rift hosts a number of peralkaline volcanic centres, with many showing signs of recent unrest. Due, in part, to the low number of historical eruptions recorded in the region, volcanism in the Main Ethiopian Rift remains understudied relative to other volcanic settings and conditions of magma storage remain almost entirely unknown. Aluto is one of these restless caldera systems and identifying magma storage conditions is vital for evaluating the risks posed by recent periods of unrest. In this study, we ran ~ 150 fractional crystallisation models, using the Rhyolite-MELTS thermodynamic software, within the range P = 50–300 MPa, starting H2O = 0.5–3 wt% and fO2 = QFM-2 − QFM + 1. This represents a realistic range of potential magma storage conditions at Aluto. We assessed the fractionation trends produced using two different starting compositions, which represent different estimates of the parental melt feeding the system. The predicted liquid lines of descent produced by these models are compared with Aluto whole-rock data from the literature, and are presented along with new observations of the natural phase assemblage and erupted mineral compositions to provide information on the magma storage conditions. Using a new, quantitative statistical approach to compare empirical data and thermodynamic model-outputs, we find that the compositions of evolved peralkaline rhyolites from Aluto are best reproduced by isobaric fractional crystallisation from a rift-related basaltic composition, without the need for significant crustal assimilation. Around 90% protracted fractional crystallisation is required to produce these compositions. This indicates that the magmatic system is likely to exist as a highly crystalline mush. The best agreement between models and natural samples is at low pressures (150 MPa), low initial H2O concentrations (0.5 wt%) and relatively high oxygen fugacity (QFM). The depth of magma storage derived from these results (~ 5.6 ± 1 km) agrees well with the source depths modelled from measured ground deformation at Aluto in 2008. Data from other peralkaline volcanic centres in the Main Ethiopian Rift, such as Boset and Gedemsa, and at other locations globally (e.g. Pantelleria, Italy) suggest that these storage conditions are a common feature of many peralkaline volcanic centres. Our data is consistent with the formation of a Daly Gap at Aluto due to compositional stratification of the magma reservoir beneath the caldera, and the non-linear relationship between temperature and SiO2 concentration during magmatic differentiation.PostprintPeer reviewe

    Expression of pro-opiomelanocortin-like gene in the testis and epididymis.

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    Constraints on radiative decay of the 17-keV neutrino from COBE Measurements

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    It is shown that, for a nontrivial radiative decay channel of the 17-keV neutrino, the photons would distort the microwave background radiation through ionization of the universe. The constraint on the branching ratio of such decays from COBE measurements is found to be more stringent than that from other considerations. The limit on the branching ratio in terms of the Compton yy parameter is Bγ<1.5×107(τν1011sec)0.45(y103)1.11h1B_\gamma < 1.5 \times 10^{-7} ({\tau_\nu \over 10^{11} sec})^{0.45} ({y \over 10^{-3}})^{1.11} h^{-1} for an Ω=1,Ωb=0.1\Omega=1, \Omega_b=0.1 universe.Comment: 7 pages. (figures will be sent on request) (To appear in Phys. Rev. D.
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