Bioactive flavanones from Luma chequen

A bioassay-guided chemical study of a methanolic extract of fresh leaves of Luma chequen led to the isolation of lumaflavanones A (1), B (2) and C (3) whose structures are proposed on the basis of NMR spectroscopic data. The structure of lumaflavanone A was confirmed by X-ray analysis. Antifeedant (Spodoptera littoralis), brine shrimp (Artemia salina) and fungistatic (Botrytis cinerea) bioassays showed that while 3 was the most active in the first two assays the mixture of 1 and 2 was more effective as a fungistatic

A model-based approach to stabilizing crutch supported paraplegic standing by artifical hip joint stiffness

The prerequisites for stable crutch supported standing were analyzed in this paper. For this purpose, a biomechanical model of crutch supported paraplegic stance was developed assuming the patient was standing with extended knees. When using crutches during stance, the crutches will put a position constraint on the shoulder, thus reducing the number of degrees of freedom. Additional hip-joint stiffness was applied to stabilize the hip joint and, therefore, to stabilize stance. The required hip-joint stiffness for changing crutch placement and hip-joint offset angle was studied under static and dynamic conditions. Modeling results indicate that, by using additional hip-joint stiffness, stable crutch supported paraplegic standing can be achieved, both under static as well as dynamic situations. The static equilibrium postures and the stability under perturbations were calculated to be dependent on crutch placement and stiffness applied. However, postures in which the hip joint was in extension (C postures) appeared to the most stable postures. Applying at least 60 N /spl middot/ m/rad hip-joint stiffness gave stable equilibrium postures in all cases. Choosing appropriate hip-joint offset angles, the static equilibrium postures changed to more erect postures, without causing instability or excessive arm forces to occur

Estimate of halo ellipticity as a function of radius with flexions

The cold dark matter theory predicts triaxial dark matter haloes. The radial distribution of halo ellipticity depends on baryonic processes and the nature of dark matter particles (collisionless or collisional). Here we show that we can use lensing flexion ratios to measure the halo ellipticity as a function of radius. We introduce a weight function and study the relationship between the first and second order statistics of flexion ratios, both of which can be used to reduce the bias in the estimate of ellipticity. we perform numerical tests for our method, and demonstrate that it can reduce the bias and determine the halo ellipticity as a function of radius. We also point out that the minimum mean flexion ratio can be used to trace the centres of galaxy clusters.Comment: 9 pages,9 figures, MNRAS accepte

Ureum als instrument om eiwitvoeding te sturen nog niet betrouwbaar: Kengetal ureumgehalte beter benutten

Wat kunnen melkveehouders met het ureumgehalte in melk? Het kengetal zegt iets over de stikstofbenutting, maar is als instrument om de eiwitvoeding van melkkoeien te sturen nu nog onvoldoende betrouwbaar. Wageningse onderzoekers pogen daar verbetering in te brenge

2-{3-Cyano-5,5-dimethyl-4-[4-(piperidin-1-yl)buta-1,3-dien­yl]-2,5-dihydro­furan-2-yl­idene}malononitrile

The title compound, C19H20N4O, crystallizes as twinned crystals containing two independent mol­ecules which pack into a three-dimensional matrix via several C—H⋯N(cyano) inter­actions, with a C⋯N range of 3.324 (8)–3.568 (8) Å and C—H⋯N angles in the range 147–166°

High-pressure phases and transitions of the layered alkaline earth nitridosilicates SrSiN2 and BaSiN2

We investigate the high-pressure phase diagram of SrSiN2 and BaSiN2 with density-functional calculation. Searching a manifold of possible candidate structures, we propose new structural modifications of SrSiN2 and BaSiN2 attainable in high-pressure experiments. The monoclinic ground state of SrSiN2 transforms at 3 GPa into an orthorhombic BaSiN2 type. At 14 GPa a CaSiN2-type structure becomes the most stable configuration of SrSiN2. A hitherto unknown Pbcm modification is adopted at 85 GPa and, finally, at 131 GPa a LiFeO2-type structure. The higher homologue BaSiN2 transforms to a CaSiN2 type at 41 GPa and further to a Pbcm modification at 105 GPa. Both systems follow the pressure-coordination rule: the coordination environment of Si increases from tetrahedral through trigonal bipyramidal to octahedral. Some high-pressure phases are related in structure through simple group–subgroup mechanisms, indicating displacive phase transformations with low activation barriers

Territorial and industry analysis of the fulfillment of Zaporizhian regional projects

The subject matter of the regional project in the context of regional and inter-regional influences has been determined. A comparative analysis of the economic potential of Dnieper economic region has been held. Characteristics and the purpose of major regional projects in Zaporizhzhya region have been established. Tendencies of the regional programs and projects use in the context of the fulfillment of the regional territory development strategy have been determined