155 research outputs found
Use of a Smartwatch for Assessment of the QT Interval in Outpatients with Coronavirus Disease 2019.
The coronavirus disease 2019 (COVID-19) pandemic has necessitated rapid implementation of innovative strategies to manage patients remotely to help reduce the risk of community and nosocomial transmission. This case demonstrates the use of an Apple Watch (Apple, Cupertino, CA, USA) to monitor for arrhythmias and QT prolongation in a patient with COVID-19 during home isolation
Coulomb Distortion Effects for (e,e'p) Reactions at High Electron Energy
We report a significant improvement of an approximate method of including
electron Coulomb distortion in electron induced reactions at momentum transfers
greater than the inverse of the size of the target nucleus. In particular, we
have found a new parametrization for the elastic electron scattering phase
shifts that works well at all electron energies greater than 300 . As an
illustration, we apply the improved approximation to the reaction
from medium and heavy nuclei. We use a relativistic ``single particle'' model
for as as applied to and to recently measured data
at CEBAF on to investigate Coulomb distortion effects while
examining the physics of the reaction.Comment: 14 pages, 3 figures, PRC submitte
Analysis of Meson Exchange and Isobar Currents in (e,e'p) Reactions from O-16
An analysis of the effects of meson exchange and isobar currents in exclusive
(e,e'p) processes from O-16 under quasi-free kinematics is presented. A model
that has probed its feasibility for inclusive quasi-elastic (e,e') processes is
considered. Sensitivity to final state interactions between the outgoing proton
and the residual nucleus is discussed by comparing the results obtained with
phenomenological optical potentials and a continuum nuclear shell-model
calculation. The contribution of the meson-exchange and isobar currents to the
response functions is evaluated and compared to previous calculations, which
differ notably from our results. These two-body contributions cannot solve the
puzzle of the simultaneous description of the different responses
experimentally separated. Copyright 1999 by The American Physical SocietyComment: 5 pages, plus 3 PS figures. To be published in Phys. Rev. C Updated
figure
Quaiselastic scattering from relativistic bound nucleons: Transverse-Longitudinal response
Predictions for electron induced proton knockout from the and
shells in O are presented using various approximations for the
relativistic nucleonic current. Results for the differential cross section,
transverse-longitudinal response () and left-right asymmetry
are compared at (GeV/c) corresponding to TJNAF experiment
89-003. We show that there are important dynamical and kinematical relativistic
effects which can be tested by experiment.Comment: 10 pages, including 2 figures. Removed preliminary experimental data
from the figure
The Effect of Chloroquine, Hydroxychloroquine and Azithromycin on the Corrected QT Interval in Patients with SARS-CoV-2 Infection
Background - The novel SARs-CoV-2 coronavirus is responsible for the global COVID-19 pandemic. Small studies have shown a potential benefit of chloroquine/hydroxychloroquine ± azithromycin for the treatment of COVID-19. Use of these medications alone, or in combination, can lead to a prolongation of the QT interval, possibly increasing the risk of Torsade de pointes (TdP) and sudden cardiac death. Methods - Hospitalized patients treated with chloroquine/hydroxychloroquine ± azithromycin from March 1st through the 23rd at three hospitals within the Northwell Health system were included in this prospective, observational study. Serial assessments of the QT interval were performed. The primary outcome was QT prolongation resulting in TdP. Secondary outcomes included QT prolongation, the need to prematurely discontinue any of the medications due to QT prolongation and arrhythmogenic death. Results - Two hundred one patients were treated for COVID-19 with chloroquine/hydroxychloroquine. Ten patients (5.0%) received chloroquine, 191 (95.0%) received hydroxychloroquine and 119 (59.2%) also received azithromycin. The primary outcome of TdP was not observed in the entire population. Baseline QTc intervals did not differ between patients treated with chloroquine/hydroxychloroquine (monotherapy group) vs. those treated with combination group (chloroquine/hydroxychloroquine and azithromycin) (440.6 ± 24.9 ms vs. 439.9 ± 24.7 ms, p =0.834). The maximum QTc during treatment was significantly longer in the combination group vs the monotherapy group (470.4 ± 45.0 ms vs. 453.3 ± 37.0 ms, p = 0.004). Seven patients (3.5%) required discontinuation of these medications due to QTc prolongation. No arrhythmogenic deaths were reported. Conclusions - In the largest reported cohort of COVID-19 patients to date treated with chloroquine/hydroxychloroquine {plus minus} azithromycin, no instances of TdP or arrhythmogenic death were reported. Although use of these medications resulted in QT prolongation, clinicians seldomly needed to discontinue therapy. Further study of the need for QT interval monitoring is needed before final recommendations can be made
Relativistic mean field approximation to the analysis of 16O(e,e'p)15N data at |Q^2|\leq 0.4 (GeV/c)^2
We use the relativistic distorted wave impulse approximation to analyze data
on 16O(e,e'p)15N at |Q^2|\leq 0.4 (GeV/c)^2 that were obtained by different
groups and seemed controversial. Results for differential cross-sections,
response functions and A_TL asymmetry are discussed and compared to different
sets of experimental data for proton knockout from p_{1/2} and p_{3/2} shells
in 16O. We compare with a nonrelativistic approach to better identify
relativistic effects. The present relativistic approach is found to accommodate
most of the discrepancy between data from different groups, smoothing a long
standing controversy.Comment: 28 pages, 7 figures (eps). Major revision made. New figures added. To
be published in Phys. Rev.
Effects of Short-Range Correlations in (e,e'p) reactions and nuclear overlap functions
A study of the effects of short-range correlations over the (e,e'p) reaction
for low missing energy in closed shell nuclei is presented. We use correlated,
quasi-hole overlap functions extracted from the asymptotic behavior of the
one-body density matrix, containing central correlations of Jastrow type, up to
first-order in a cluster expansion, and computed in the very high asymptotic
region, up to 100 fm. The method to extract the overlap functions is checked in
a simple shell model, where the exact results are known. We find that the
single-particle wave functions of the valence shells are shifted to the right
due to the short-range repulsion by the nuclear core. The corresponding
spectroscopic factors are reduced only a few percent with respect to the shell
model. However, the (e,e'p) response functions and cross sections are enhanced
in the region of the maximum of the missing momentum distribution due to
short-range correlations.Comment: 45 pages, 15 figure
Meson Exchange Currents in (e,e'p) recoil polarization observables
A study of the effects of meson-exchange currents and isobar configurations
in reactions is presented. We use a distorted wave
impulse approximation (DWIA) model where final-state interactions are treated
through a phenomenological optical potential. The model includes relativistic
corrections in the kinematics and in the electromagnetic one- and two-body
currents. The full set of polarized response functions is analyzed, as well as
the transferred polarization asymmetry. Results are presented for proton
knock-out from closed-shell nuclei, for moderate to high momentum transfer.Comment: 44 pages, 18 figures. Added physical arguments explaining the
dominance of OB over MEC, and a summary of differences with previous MEC
calculations. To be published in PR
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Heterogeneous Agglomeration
Many prior treatments of agglomeration explicitly or implicitly assume that all industries agglomerate for the same reasons. This paper uses U.K. establishment-level coagglomeration data to document substantial heterogeneity across industries in the microfoundations of agglomeration economies. It finds robust evidence of organizational and adaptive agglomeration forces as discussed by Chinitz (1961), Vernon (1960), and Jacobs (1969). These forces interact with the traditional Marshallian (1890) factors of input sharing, labor pooling, and knowledge spillovers, establishing a previously unrecognized complementarity between the approaches of Marshall and Jacobs, as well as others, to the analysis of agglomeration
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