9,505 research outputs found
Dynamics and stability of wind turbine generators
Synchronous and induction generators are considered. A comparison is made between wind turbines, steam, and hydro units. The unusual phenomena associated with wind turbines are emphasized. The general control requirements are discussed, as well as various schemes for torsional damping such as speed sensitive stabilizer and blade pitch control. Integration between adjacent wind turbines in a wind farm is also considered
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The nurses that roared: nurses from history who found their voices and challenged the status quo
In this article we explore how nurses from history challenged norms of nursing and society, and consider how they can influence and inspire nurses today. We discuss the role of nurses in the fight for women’s suffrage, campaigning for the vote and caring for women who suffered in their fight to achieve it, and present examples of outstanding bravery in the past and present day. The article contains examples of the bravery of some relatively unknown nurses in wartime, who also fought for equality and inclusion, and nurses who challenged the care of marginalised groups, campaigning for improved treatment, sometimes at great personal cost. Finally we consider the courage of present-day nurses. Drawing on the global campaign of “Nursing Now”, we suggest that learning from these exceptional nurses and acknowledging and highlighting their contribution can inspire us to strengthen and promote nursing and to empower women globally
Odd-parity perturbations of self-similar Vaidya spacetime
We carry out an analytic study of odd-parity perturbations of the
self-similar Vaidya space-times that admit a naked singularity. It is found
that an initially finite perturbation remains finite at the Cauchy horizon.
This holds not only for the gauge invariant metric and matter perturbation, but
also for all the gauge invariant perturbed Weyl curvature scalars, including
the gravitational radiation scalars. In each case, `finiteness' refers to
Sobolev norms of scalar quantities on naturally occurring spacelike
hypersurfaces, as well as pointwise values of these quantities.Comment: 28 page
Jahn-Teller Distortions and the Supershell Effect in Metal Nanowires
A stability analysis of metal nanowires shows that a Jahn-Teller deformation
breaking cylindrical symmetry can be energetically favorable, leading to stable
nanowires with elliptic cross sections. The sequence of stable cylindrical and
elliptical nanowires allows for a consistent interpretation of experimental
conductance histograms for alkali metals, including both the shell and
supershell structures. It is predicted that for gold, elliptical nanowires are
even more likely to form since their eccentricity is smaller than for alkali
metals. The existence of certain metastable ``superdeformed'' nanowires is also
predicted
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The Levelised Cost of Frequency Control Ancillary Services in Australia’s National Electricity Market
Over the period 2016-2021 Australia’s National Electricity Market (NEM) experienced an investment supercycle, with 16,000MW of new utility-scale variable renewable plant commitments (and an additional 8,000MW of rooftop solar PV) in a power system with a ratcheted peak demand of 35,000MW. The sharp rise in intermittent asynchronous resources and the disorderly loss of 5,000MW of synchronous coal-fired generation plant placed strains on system security – most visibly represented by the rapid deterioration in the distribution of the power systems’ (50Hz) Frequency. This in turn necessitated material changes to the NEM’s suite of Frequency Control Ancillary Service (FCAS) markets. Utility-scale batteries are ideally suited for FCAS duties, but unlike the wholesale electricity market, there is no forward price curve for Frequency Control Ancillary Services, nor is there any systematic framework for determining equilibrium prices that might otherwise be used for investment decision-making. In this article, we develop an approach for quantifying long run equilibrium prices in the markets for Frequency Control Ancillary Services, with the intended application being to guide the suitability of utility-scale battery investments under conditions of uncertainty and missing forward FCAS markets
A process-based approach to health-related quality of life as a “way of living”
Introduction
There is an historical initiative to establish common theoretical ground to support a framework for assessing health-related quality of life (HRQL). Our aim was to add to this effort with an analysis of theoretical/philosophical themes embedded in HRQL questionnaires and patient reports.
Methods and Results
We reviewed recent developments in HRQL assessment. This included analyzing a representative sample of psychometric measures of HRQL to schematically summarize core theoretical/philosophical themes that are embedded in questionnaire items. This analysis indicated a state-based framework for HRQL that was characterized by themes of hedonic and eudaimonic well-being, and desire-satisfaction. In contrast, a review of patient reports of HRQL indicated a process-based framework where goal-directed activities aimed to secure aspirational life goals while striving to accept the reality of declining health. Given this difference in HRQL themes we used a meta-philosophical approach, based on Hadot’s idea of philosophy as a way of living, to identify a process-based theoretical framework for HRQL assessment that addressed patient-reported themes. The Stoic modification of eudaimonic well-being was examined where HRQL and well-being are viewed as a process (vs. state) aimed at transforming the experience of loss or grief in response to adversity through goal-directed activities/exercises (euroia biou, good flow in life). We then introduced a complementary research agenda for HRQL assessment that incorporates self-reported, goal-directed activities that are initiated or maintained to promote HRQL.
Conclusion
A process-based approach to HRQL assessment may increase the spectrum of clinically relevant features that currently comprise operational measures of this patient-reported appraisal
Screening of retroviral cDNA libraries for factors involved in protein phosphorylation in signaling cascades
We report a novel approach that allows for the rapid identification of proteins mediating phosphorylation in signaling cascades after specific stimulation. As a proof of concept, we used the interferon- γ (IFN-γ)-induced phosphorylation of signal transducer and activator of transcription-1 (Stat1) in a human promonocytic cell line, which was previously shown to be deficient in this signaling pathway. By using retroviral cDNA expression libraries, transduced selector cells expressing single cDNAs were stimulated with IFN-γ, then fixed, permeabilized and stained intracellularly for phospho-Stat1 levels. Cells responding to the stimulation, which showed increased levels of phosphorylated Stat1, were enriched using fluorescence activated cell sorting (FACS). Genomic DNA was isolated from the enriched cell population and served as a template for cDNA amplification using PCR. After only one round of selection, a cDNA encoding the β-chain of the IFN-γ receptor (IFNGR2) was obtained and demonstrated to restore the selected phenotype. The approach now allows one to use phospho-events as reporters, alone or in tandem, for screening of signaling network states, overcoming a prior need to rely on the reporter genes that are often only indirect measures of phenotypes desired in a screen
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