The Warwick Hip Trauma Evaluation Two - an abridged protocol for the WHiTE Two Study AN EMBEDDED RANDOMISED TRIAL COMPARING THE DUAL-MOBILITY WITH POLYETHYLENE CUPS IN HIP ARTHROPLASTY FOR FRACTURE

Fractures of the proximal femur are one of the greatest challenges facing the medical community, constituting a heavy socioeconomic burden worldwide. Controversy exists regarding the optimal treatment for independent patients with displaced intracapsular fractures of the proximal femur. The recognised alternatives are hemiarthroplasty and total hip replacement. At present there is no established standard of care, with both types of arthroplasty being used in many centres. The principal advantages of total hip replacement are a functional benefit over hemiarthroplasty and a reduced risk of revision surgery. The principal criticism is the increased risk of dislocation. We believe that an alternative acetabular component may reduce the risk of dislocation but still provide the functional benefit of total hip replacement in these patients. We therefore propose to investigate the dislocation risk of a dual-mobility acetabular component compared with standard polyethylene component in total hip replacement for independent patients with displaced intracapsular fractures of the proximal femur within the framework of the larger WHiTE (Warwick Hip Trauma Evaluation) Comprehensive Cohort Study. Cite this article: Bone Joint Res 2013;2:210–13

Ectoplasm & Superspace Integration Measure for 2D Supergravity with Four Spinorial Supercurrents

Building on a previous derivation of the local chiral projector for a two dimensional superspace with eight real supercharges, we provide the complete density projection formula required for locally supersymmetrical theories in this context. The derivation of this result is shown to be very efficient using techniques based on the Ectoplasmic construction of local measures in superspace.Comment: 18 pages, LaTeX; V2: minor changes, typos corrected, references added; V3: version to appear in J. Phys. A: Math. Theor., some comments and references added to address a referee reques

A New Calibration Of Galactic Cepheid Period-Luminosity Relations From B To K Bands, And A Comparison To LMC Relations

Context. The universality of the Cepheid period-luminosity (PL) relations has been under discussion since metallicity effects were assumed to play a role in the value of the intercept and, more recently, of the slope of these relations. Aims. The goal of the present study is to calibrate the Galactic PL relations in various photometric bands (from B to K) and to compare the results to the well-established PL relations in the LMC. Methods. We use a set of 59 calibrating stars, the distances of which are measured using five different distance indicators: Hubble Space Telescope and revised Hipparcos parallaxes, infrared surface brightness and interferometric Baade-Wesselink parallaxes, and classical Zero-Age-Main-Sequence-fitting parallaxes for Cepheids belonging to open clusters or OB stars associations. A detailed discussion of absorption corrections and projection factor to be used is given. Results. We find no significant difference in the slopes of the PL relations between LMC and our Galaxy. Conclusions. We conclude that the Cepheid PL relations have universal slopes in all photometric bands, not depending on the galaxy under study (at least for LMC and Milky Way). The possible zero-point variation with metal content is not discussed in the present work, but an upper limit of 18.50 for the LMC distance modulus can be deduced from our data.McDonald Observator

The SU(N) Matrix Model at Two Loops

Multi-loop calculations of the effective action for the matrix model are important for carrying out tests of the conjectured relationship of the matrix model to the low energy description of M-theory. In particular, comparison with N-graviton scattering amplitudes in eleven-dimensional supergravity requires the calculation of the effective action for the matrix model with gauge group SU(N). A framework for carrying out such calculations at two loops is established in this paper. The two-loop effective action is explicitly computed for a background corresponding to the scattering of a single D0-brane from a stack of N-1 D0-branes, and the results are shown to agree with known results in the case N=2.Comment: 30 pages, 1 figure; v2 - typos corrected, references update

Eleven-dimensional massless superparticles and matrix theory spin-orbit couplings revisited

The classical probe dynamics of the eleven-dimensional massless superparticles in the background geometry produced by N source M-momenta is investigated in the framework of N-sector DLCQ supergravity. We expand the probe action up to the two fermion terms and find that the fermionic contributions are the spin-orbit couplings, which precisely agree with the matrix theory calculations. We comment on the lack of non-perturbative corrections in the one-loop matrix quantum mechanics effective action and its compatibility with the supergravity analysis.Comment: 11 pages, Latex, no figure

On A Superfield Extension of The ADHM Construction and N=1 Super Instantons

We give a superfield extension of the ADHM construction for the Euclidean theory obtained by Wick rotation from the Lorentzian four dimensional N=1 super Yang-Mills theory. In particular, we investigate the procedure to guarantee the Wess-Zumino gauge for the superfields obtained by the extended ADHM construction, and show that the known super instanton configurations are correctly obtained.Comment: 22 pages, LaTeX, v2: typos corrected, references adde

Synthetic RNA Silencing of Actinorhodin Biosynthesis in Streptomyces coelicolor A3(2)

We demonstrate the first application of synthetic RNA gene silencers in Streptomyces coelicolor A3(2). Peptide nucleic acid and expressed antisense RNA silencers successfully inhibited actinorhodin production. Synthetic RNA silencing was target-specific and is a new tool for gene regulation and metabolic engineering studies in Streptomyces.Peer reviewe

Wess-Zumino Terms in Supersymmetric Gauge Theories

The Wess-Zumino term is constructed for supersymmetric QCD with two colors and flavors, and is shown to correctly reproduce the anomalous Ward identities. Supersymmetric QCD is also shown not to have topologically stable skyrmion solutions because of baryon flat directions, which allow them to unwind. The generalization of these results to other supersymmetric theories with quantum modified constraints is discussed.Comment: 4 pages (revtex

Effective Average Action in N=1 Super-Yang-Mills Theory

For N=1 Super-Yang-Mills theory we generalize the effective average action Gamma_k in a manifest supersymmetric way using the superspace formalism. The exact evolution equation for Gamma_k is derived and, introducing as an application a simple truncation, the standard one-loop beta-function of N=1 SYM theory is obtained.Comment: 17 pages, LaTeX, some remarks added, misprints corrected, to appear in Phys. Rev.