Note on double reflection and algebraicity of holomorphic mappings

In this note, our purpose is to establish shortly the algebraicity of a holomorphic mapping between real algebraic CR manifolds under a double reflection condition which generalizes the classical single reflection. A complete study of various double reflection conditions is also provided.Comment: 26 pages, LaTex, submitte

On removable singularities for integrable CR functions

We endeavour a systematic approach for the removal of singularities for CR functions on an arbitrary embeddable CR manifold.Comment: 38 pages, LaTeX. To appear in Indiana Univ. Math. J. 199

On the local meromorphic extension of CR meromorphic mappings

Let $M$ be a generic CR submanifold in \C^{m+n}, $m= CRdim M \geq 1$,$n=codim M \geq 1$, $d=dim M = 2m+n$. A CR meromorphic mapping (in the sense of Harvey-Lawson) is a triple $(f,{\cal D}_f, [\Gamma_f])$, where: 1. $f: {\cal D}_f \to Y$ is a ${\cal C}^1$-smooth mapping defined over a dense open subset ${\cal D}_f$ of $M$ with values in a projective manifold $Y$; 2. The closure $\Gamma_f$ of its graph in \C^{m+n} \times Y defines a oriented scarred ${\cal C}^1$-smooth CR manifold of CR dimension $m$ (i.e. CR outside a closed thin set) and 3. Such that $d[\Gamma_f]=0$ in the sense of currents. We prove in this paper that $(f,{\cal D}_f, [\Gamma_f])$ extends meromorphically to a wedge attached to $M$ if $M$ is everywhere minimal and ${\cal C}^{\omega}$ (real analytic) or if $M$ is a ${\cal C}^{2,\alpha}$ globally minimal hypersurface.Comment: 25 pages, LaTeX. To appear in Ann. Pol. Math. 199

Lean Construction Implementation: Case Study

Lean construction offers a collaborative approach to traditional construction practices and has the primary goal of increasing value to the client. With the proper use of lean construction tools on projects and the adoption of a lean culture, construction companies have recognized real benefits in terms of cost, productivity, and schedule while increasing customer satisfaction. The construction industry has been slow however in adopting the lean construction practices that have proven to be successful. The research in this study will familiarize the reader with the principles of lean construction, and address why the demand for lean construction is rising. In this case study, participants from two construction companies, a leading lean contractor and a non-lean contractor, were interviewed to evaluate the different lean construction “journeys” taken by each company. The interviews and analysis in this study primarily focus on the lean culture, use of lean construction tools, common barriers, lean education, and industry outlook from each of the companies. Suggestions for the future growth of lean construction were provided based on the interview responses

Accelerator measurement of the energy spectra of neutrons emitted in the interaction of 3-GeV protons with several elements

The application of time of flight techniques for determining the shapes of the energy spectra of neutrons between 20 and 400 MeV is discussed. The neutrons are emitted at 20, 34, and 90 degrees in the bombardment of targets by 3 GeV protons. The targets used are carbon, aluminum, cobalt, and platinum with cylindrical cross section. Targets being bombarded are located in the internal circulating beam of a particle accelerator

Preferential utilization of NADPH as the endogenous electron donor for NAD(P)H:quinone oxidoreductase 1 (NQO1) in intact pulmonary arterial endothelial cells

The goal was to determine whether endogenous cytosolic NAD(P)H:quinone oxidoreductase 1 (NQO1) preferentially uses NADPH or NADH in intact pulmonary arterial endothelial cells in culture. The approach was to manipulate the redox status of the NADH/NAD+ and NADPH/NADP+ redox pairs in the cytosolic compartment using treatment conditions targeting glycolysis and the pentose phosphate pathway alone or with lactate, and to evaluate the impact on the intact cell NQO1 activity. Cells were treated with 2-deoxyglucose, iodoacetate, or epiandrosterone in the absence or presence of lactate, NQO1 activity was measured in intact cells using duroquinone as the electron acceptor, and pyridine nucleotide redox status was measured in total cell KOH extracts by high-performance liquid chromatography. 2-Deoxyglucose decreased NADH/NAD+ and NADPH/NADP+ ratios by 59 and 50%, respectively, and intact cell NQO1 activity by 74%; lactate restored NADH/NAD+, but not NADPH/NADP+ or NQO1 activity. Iodoacetate decreased NADH/NAD+ but had no detectable effect on NADPH/NADP+ or NQO1 activity. Epiandrosterone decreased NQO1 activity by 67%, and although epiandrosterone alone did not alter the NADPH/NADP+ or NADH/NAD+ ratio, when the NQO1 electron acceptor duroquinone was also present, NADPH/NADP+ decreased by 84% with no impact on NADH/NAD+. Duroquinone alone also decreased NADPH/NADP+ but not NADH/NAD+. The results suggest that NQO1 activity is more tightly coupled to the redox status of the NADPH/NADP+ than NADH/NAD+ redox pair, and that NADPH is the endogenous NQO1 electron donor. Parallel studies of pulmonary endothelial transplasma membrane electron transport (TPMET), another redox process that draws reducing equivalents from the cytosol, confirmed previous observations of a correlation with the NADH/NAD+ ratio

Characterization of theThreshold for NAD(P)H:quinone Oxidoreductase Activity in Intact Sulforaphane-treated Pulmonary Arterial Endothelial Cells

Treatment of bovine pulmonary arterial endothelial cells in culture with the phase II enzyme inducer sulforaphane (5 μM, 24 h; sulf-treated) increased cell-lysate NAD(P)H:quinone oxidoreductase (NQO1) activity by 5.7 ± 0.6 (mean ± SEM)-fold, but intact-cell NQO1 activity by only 2.8 ± 0.1-fold compared to control cells. To evaluate the hypothesis that the threshold for sulforaphane-induced intact-cell NQO1 activity reflects a limitation in the capacity to supply NADPH at a sufficient rate to drive all the induced NQO1 to its maximum activity, total KOH-extractable pyridine nucleotides were measured in cells treated with duroquinone to stimulate maximal NQO1 activity. NQO1 activation increased NADP+ in control and sulf-treated cells, with the effect more pronounced in the sulf-treated cells, in which the NADPH was also decreased. Glucose-6-phosphate dehydrogenase (G-6-PDH) inhibition partially blocked NQO1 activity in control and sulf-treated cells, but G-6-PDH overexpression via transient transfection with the human cDNA alleviated neither the restriction on intact sulf-treated cell NQO1 activity nor the impact on the NADPH/NADP+ ratios. Intracellular ATP levels were not affected by NQO1 activation in control or sulf-treated cells. An increased dependence on extracellular glucose and a rightward shift in the Km for extracellular glucose were observed in NQO1-stimulated sulf-treated vs control cells. The data suggest that glucose transport in the sulf-treated cells may be insufficient to support the increased metabolic demand for pentose phosphate pathway-generated NADPH as an explanation for the NQO1 threshold